References
- Adams LS, Seeram NP, Hardy ML, Carpenter C, Heber D (2006). Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. Evid Based Complement Alternat Med, 3, 117-24. https://doi.org/10.1093/ecam/nel001
- Alison MR, Murphy G, Leedham S (2008). Stem cells and cancer: a deadly mix. Cell Tissue Res, 331, 109-24. https://doi.org/10.1007/s00441-007-0510-7
- Bleau AM, Hambardzumyan D, Ozawa T, et al (2009). PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell, 4, 226-35. https://doi.org/10.1016/j.stem.2009.01.007
- Chang WT, Li J, Haung HH, et al (2011). Baicalein protects against doxorubicin-induced cardiotoxicity by attenuation of mitochondrial oxidant injury and JNK activation. J Cell Biochem, 112, 2873-81. https://doi.org/10.1002/jcb.23201
- Dean M (2009). ABC transporters, drug resistance, and cancer stem cells. J Mammary Gland Biol Neoplasia, 14, 3-9. https://doi.org/10.1007/s10911-009-9109-9
- Di X, Shiu RP, Newsham IF, Gewirtz DA (2009). Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin. Biochem Pharmacol, 77, 1139-50. https://doi.org/10.1016/j.bcp.2008.12.016
- Dmoszynska A (2008). Diagnosis and the current trends in multiple myeloma therapy. Pol Arch Med Wewn, 118, 563-6.
- Feng Y, Wen J, Mike P, et al (2010).Bone marrow stromal cells from myeloma patients support the growth of myeloma stem cells. Stem Cells Dev, 19, 1289-96. https://doi.org/10.1089/scd.2010.0010
- Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC (1996). Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med, 183, 1797-806. https://doi.org/10.1084/jem.183.4.1797
- Goodell MA, Rosenzweig M, Kim H, et al (1997).Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med, 3, 1337-45. https://doi.org/10.1038/nm1297-1337
- Hiraga T, Ito S, Nakamura H (2011).Side population in MDAMB- 231 human breast cancer cells exhibits cancer stem cell-like properties without higher bone-metastatic potential. Oncol Rep, 25, 289-96.
- Hu L, McArthur C, Jaffe RB (2010).Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant. Br J Cancer, 102, 1276-83. https://doi.org/10.1038/sj.bjc.6605626
- Huang KF, Zhang GD, Huang YQ, Diao Y (2012). Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway. Int Immunopharmacol, 12, 334-41. https://doi.org/10.1016/j.intimp.2011.12.004
- Ikezoe T, Chen SS, Heber D, Taguchi H, Koeffler HP (2001). Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest. Prostate, 49, 285-92. https://doi.org/10.1002/pros.10024
- Jakubikova J, Adamia S, Kost-Alimova M, et al (2011). Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications. Blood, 117, 4409-19. https://doi.org/10.1182/blood-2010-02-267344
- Jemal A, Siegel R, Ward E, et al (2008). Cancer statistics. CA Cancer J Clin, 58, 71-96. https://doi.org/10.3322/CA.2007.0010
- Jordan CT (2009). Cancer stem cells: controversial or just misunderstood? Cell Stem Cell, 4, 203-5. https://doi.org/10.1016/j.stem.2009.02.003
- Jung HS, Kim MH, Gwak NG, et al (2012). Antiallergic effects of Scutellaria baicalensis on inflammation in vivo and in vitro. J Ethnopharmacol, 141, 345-9. https://doi.org/10.1016/j.jep.2012.02.044
- Kabashima A, Higuchi H, Takaishi H, et al (2009).Side population of pancreatic cancer cells predominates in TGFbeta- mediated epithelial to mesenchymal transition and invasion. Int J Cancer, 124, 2771-9. https://doi.org/10.1002/ijc.24349
- Katayama R, Koike S, Sato S, et al (2009).Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRPmediated drug export. Cancer Sci, 100, 2060-8. https://doi.org/10.1111/j.1349-7006.2009.01288.x
- Kong QL, Hu LJ, Cao JY, et al (2010).Epstein-Barr virusencoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma. PLoS Pathog, 6, e1000940. https://doi.org/10.1371/journal.ppat.1000940
- Kumagai T, Muller CI, Desmond JC, et al (2007). Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. Leuk Res, 31, 523-30. https://doi.org/10.1016/j.leukres.2006.08.019
- Lee JC, Tseng CK, Wu SF, et al (2011). San-Huang-Xie-Xin-Tang extract suppresses hepatitis C virus replication and virus-induced cyclooxygenase-2 expression. J Viral Hepat, 18, e315-24. https://doi.org/10.1111/j.1365-2893.2010.01424.x
- Li H, Gao Q, Guo L, Lu SH (2011). The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. Cancer Biol Ther, 11, 950-8. https://doi.org/10.4161/cbt.11.11.15531
- Liang RR, Zhang S, Qi JA, et al (2012). Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling. Int J Oncol .
- Liu S, Ma Z, Cai H, et al (2010). Inhibitory effect of baicalein cells. Eur J Haematol, 84, 137-44. https://doi.org/10.1111/j.1600-0609.2009.01365.x
- Li-Weber M (2009). New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Cancer Treat Rev, 35, 57-68. https://doi.org/10.1016/j.ctrv.2008.09.005
- Li-Weber M (2010). Targeting apoptosis pathways in cancer by Chinese medicine. Cancer Lett .
- Loh YS, Mo S, Brown RD, et al (2008).Presence of Hoechst low side populations in multiple myeloma. Leuk Lymphoma, 49, 1813-6. https://doi.org/10.1080/10428190802272676
- Ma Z, Otsuyama K, Liu S, et al (2005). Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells. Blood, 105, 3312-8. https://doi.org/10.1182/blood-2004-10-3915
- Marshall CB, Krofft RD, Pippin JW, Shankland SJ (2010).CDK inhibitor p21 is prosurvival in adriamycin-inducedpodocyte injury, in vitro and in vivo. Am J Physiol RenalPhysiol, 298, F1140-51. https://doi.org/10.1152/ajprenal.00216.2009
- Matsui W, Wang Q, Barber JP, et al (2008). Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance. Cancer Res, 68, 190-7. https://doi.org/10.1158/0008-5472.CAN-07-3096
- Mo SL, Li J, Loh YS, et al (2011). Factors influencing the abundance of the side population in a human myeloma cell line. Bone Marrow Res, 2011, 524845.
- Moitra K, Lou H, Dean M (2011). Multidrug efflux pumps and cancer stem cells: insights into multidrug resistance and therapeutic development. Clin Pharmacol Ther, 89, 491-502. https://doi.org/10.1038/clpt.2011.14
- Moserle L, Indraccolo S, Ghisi M, et al (2008).The side population of ovarian cancer cells is a primary target of IFNalpha antitumor effects. Cancer Res, 68, 5658-68. https://doi.org/10.1158/0008-5472.CAN-07-6341
- Nishii T, Yashiro M, Shinto O, et al (2009).Cancer stem cell-like SP cells have a high adhesion ability to the peritoneum in gastric carcinoma. Cancer Sci, 100, 1397-402. https://doi.org/10.1111/j.1349-7006.2009.01211.x
- Parajuli P, Joshee N, Chinni SR, et al (2011). Delayed growth of glioma by Scutellaria flavonoids involve inhibition of Akt, GSK-3 and NF-kappaB signaling. J Neurooncol, 101, 15-24. https://doi.org/10.1007/s11060-010-0221-x
- Parajuli P, Joshee N, Rimando AM, Mittal S, Yadav AK (2009). In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. Planta Med, 75, 41-8. https://doi.org/10.1055/s-0028-1088364
- Pfister O, Oikonomopoulos A, Sereti KI, et al (2008). Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells. Circ Res, 103, 825-35. https://doi.org/10.1161/CIRCRESAHA.108.174615
- Saigal S, Bhargava A (2011). Stem cell--is there any role in tumorigenic activity. Turk Patoloji Derg, 27, 93-7 (in Turkish).
- Salcido CD, Larochelle A, Taylor BJ, Dunbar CE, Varticovski L (2010).Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer. Br J Cancer, 102, 1636-44. https://doi.org/10.1038/sj.bjc.6605668
- Shi Y, Fu X, Hua Y, et al (2012).The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells. PLoS One, 7, e33358. https://doi.org/10.1371/journal.pone.0033358
- Taniguchi D, Takahara O, Takasaki Y, et al (2009). Fatal cytomegalovirus pneumonia and associated Herpes virus infection in a relapsed/refractory multiple myeloma patient treated with bortezomib plus dexamethasone. Case Rep Oncol, 2, 140-3. https://doi.org/10.1159/000228161
- Van Valckenborgh E, Matsui W, Agarwal P, et al (2012).Tumorinitiating capacity of CD138- and CD138+ tumor cells in the 5T33 multiple myeloma model. Leukemia, 26, 1436-9. https://doi.org/10.1038/leu.2011.373
- Wang CZ, Li XL, Wang QF, Mehendale SR, Yuan CS (2010). Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. Phytomedicine, 17, 63-8. https://doi.org/10.1016/j.phymed.2009.07.003
- Wu C, Alman BA (2008). Side population cells in human cancers. Cancer Lett, 268, 1-9. https://doi.org/10.1016/j.canlet.2008.03.048
- Wu C, Wei Q, Utomo V, et al (2007). Side population cells isolated from mesenchymal neoplasms have tumor initiating potential. Cancer Res, 67, 8216-22. https://doi.org/10.1158/0008-5472.CAN-07-0999
- Xu Y, Xia F, Ma L, et al (2011). MicroRNA-122 sensitizes HCC cancer cells to adriamycin and vincristine through modulating expression of MDR and inducing cell cycle arrest. Cancer Lett, 310, 160-9.
- Ye F, Che Y, McMillen E, et al (2009).The effect of Scutellaria baicalensis on the signaling network in hepatocellular carcinoma cells. Nutr Cancer, 61, 530-7. https://doi.org/10.1080/01635580902803719
- Zhou S, Schuetz JD, Bunting KD, et al (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the sidepopulation phenotype. Nat Med, 7, 1028-34. https://doi.org/10.1038/nm0901-1028
Cited by
- Immune and Anti-oxidant Functions of Ethanol Extracts of Scutellaria baicalensis Georgi in Mice Bearing U14 Cervical Cancers vol.15, pp.10, 2014, https://doi.org/10.7314/APJCP.2014.15.10.4129
- Wogonin modulates hydroperoxide-induced apoptosis via PI3K/Akt pathway in retinal pigment epithelium cells vol.9, pp.1, 2014, https://doi.org/10.1186/s13000-014-0154-3
- Agrobacterium-mediated transformation of thin cell layer explants of Scutellaria ocmulgee small: a rare plant with anti-tumor properties vol.127, pp.1, 2016, https://doi.org/10.1007/s11240-016-1029-y
- Anticancer properties of baicalein: a review vol.25, pp.8, 2016, https://doi.org/10.1007/s00044-016-1607-x
- Cancer Stem Cells: The Potential Targets of Chinese Medicines and Their Active Compounds vol.17, pp.6, 2016, https://doi.org/10.3390/ijms17060893
- The Fascinating Effects of Baicalein on Cancer: A Review vol.17, pp.10, 2016, https://doi.org/10.3390/ijms17101681
- and Cancer Treatment: Recent Progress and Perspectives in Biomedical and Clinical Studies vol.46, pp.01, 2018, https://doi.org/10.1142/S0192415X18500027
- Synthesis of 5-Hydroxy-3′,4′,7-trimethoxyflavone and Related Compounds and Elucidation of Their Reversal Effects on BCRP/ABCG2-Mediated Anticancer Drug Resistance pp.14394227, 2019, https://doi.org/10.1002/cbic.201800431
- Effect of Cinnamic acid and FOLFOX in diminishing side population and downregulating cancer stem cell markers in colon cancer cell line HT-29 vol.26, pp.1, 2018, https://doi.org/10.1007/s40199-018-0210-8