Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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Effect of fermented soybean curd residue (FSCR; SCR-meju) by aspergillus oryzae on the anti-obesity and lipids improvement

Aspergillus Oryzae로 발효시킨 비지메주의 항비만 및 지질개선 효과

  • Lee, Sang-Il (Department of Food, Nutrition and Culinary Arts, Keimyung College) ;
  • Lee, Ye-Kyung (Center for Nutraceutical and Pharmaceutical Materials, Myongji University) ;
  • Kim, Soon-Dong (Center for Nutraceutical and Pharmaceutical Materials, Myongji University) ;
  • Lee, Ji-Ean (Center for Nutraceutical and Pharmaceutical Materials, Myongji University) ;
  • Choi, Jongkeu (Department of Cosmetic Science, Chungwoon University) ;
  • Bak, Jong-Phil (Center for Nutraceutical and Pharmaceutical Materials, Myongji University) ;
  • Lim, Jong-Hwan (Center for Nutraceutical and Pharmaceutical Materials, Myongji University) ;
  • Suh, Joo-Won (Center for Nutraceutical and Pharmaceutical Materials, Myongji University) ;
  • Lee, In-Ae (Center for Nutraceutical and Pharmaceutical Materials, Myongji University)
  • 이상일 (계명문화대학 식품영양조리학부) ;
  • 이예경 (명지대학교 농생명바이오식의약소재개발사업단) ;
  • 김순동 (명지대학교 농생명바이오식의약소재개발사업단) ;
  • 이지언 (명지대학교 농생명바이오식의약소재개발사업단) ;
  • 최종근 (청운대학교 화장품과학과) ;
  • 박종필 (명지대학교 농생명바이오식의약소재개발사업단) ;
  • 임종환 (명지대학교 농생명바이오식의약소재개발사업단) ;
  • 서주원 (명지대학교 농생명바이오식의약소재개발사업단) ;
  • 이인애 (명지대학교 농생명바이오식의약소재개발사업단)
  • Received : 2013.09.02
  • Accepted : 2013.11.20
  • Published : 2013.12.31
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Abstract

In this study, we designed to confirm the dietary effect of anti-obesity of fermented soybean curd residue (FSCR; SCR-Meju; Biji-meju) by A. oryzae, which is well known as a Korean traditional meju microbe. We observed that body weight gain, serum and hepatic lipid profile, as well as the activity of ROS generating enzyme and ROS scavenging enzyme in high-fat diet induced obese mice fed experimental diet (SCR and SCR-meju). Body weight gain and epididymal fat weight of HC (high-fat diet control) was markedly higher than that of NC (Normal control). Conversely, body weight gain and epididymal fat weight of the SCR (Biji) and SCR-meju (Biji-meju) group was significantly lower than that of HC; these of the SCR-meju group was lower than that of the SCR group. Furthermore, serum TG and total-cholesterol and LDL-cholesterol contents of SCR and SCR-meju groups were lower than that of HC, and HDL-cholesterol level of the SCR-meju group was significantly higher than that of HC. In conclusion, although precise mechanisms of the antiobese effects of SCR-meju in this study are unknown, the present study provides an experimental evidence that SCR-meju may prevent obesity and obesity related metabolic syndromes, such as hyperlipidemia, hypertension and diabetes, and liver disease by high-fat diet. Nevertheless, further study in this filed will be needed.

Keywords

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