Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)

Korean Magnetic Resonance Society (한국자기공명학회)
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NMR Study of Consensus DNA-binding Site for Arabidopsis thaliana Class I Transcription Factor AtTCP1

  • Choi, Yong-Geun (Department of Chemistry and RINS, Gyeongsang National University) ;
  • Kim, Hee-Eun (Department of Chemistry and RINS, Gyeongsang National University) ;
  • Lee, Joon-Hwa (Department of Chemistry and RINS, Gyeongsang National University)
  • Received : 2013.10.14
  • Accepted : 2013.10.28
  • Published : 2013.12.20
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Abstract

The TCP domain is a DNA-binding domain present in plant transcription factors and has a similar structural feature to the bHTH motif of eukaryotic transcription factors. The imino proton exchange study has been performed for the DNA duplex containing the consensus DNA-binding site for the AtTCP11 transcription factor. The first two base pairs in the consensus 5'-GTGGG-3' sequence are relatively very unstable but lead to greater stabilization of the neighboring two G C base pairs. These unique dynamic features of the five base pairs in the consensus DNA sequence might play crucial roles in the effective DNA binding of the AtTCP11 protein.

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References

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