Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Dietary Intake and Venous Blood Concentration of Polycyclic Aromatic Hydrocarbons in Low-level Exposure

다환방향족탄화수소류의 음식물을 통한 섭취량과 혈중농도

  • Moon, Chan-Seok (Department of Industrial Health, Catholic University of Pusan)
  • 문찬석 (부산가톨릭대학교 산업보건학과)
  • Received : 2012.05.10
  • Accepted : 2012.09.25
  • Published : 2012.10.31
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Abstract

Objectives: This study aims to evaluate the blood concentrations and dietary intake for 24-hour food duplicate of low level polycyclic aromatic hydrocarbons (PAHs). Design: The geometric means of the blood concentrations and dietary intake of 16 PAHs in college student candidates were simply compared with instrumental detection. Methods: The concentrations of 16 PAHs in venous blood and 24-hour food duplicates were analyzed with head-space solid phase microextraction (HS-SPME) of gas chromatography-mass spectrometry. Results: Naphthalene, acenaphthylene, pyrene, benz(a)anthracene, chrysene, and acenaphthene among the 16 analyzed PAHs were simultaneously detected both in venous blood and 24-hour food duplicate samples. Conclusion: The main exposure source of the six PAHs is thought to be oral intake from food through low level non-occupational exposure.

Keywords

References

  1. Boffetta P, Jourenkova N, Custavsson P. Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons. Cancer Causes & Control. 1997; 444-472.
  2. International Agency for Research on Cancer. Certain polycyclic aromatic hydrocarbons and heterocyclic compounds. In: IARC monographs on the evaluation of carcinogenic risks to humans Vol. 3 Lyon, France: International Agency for Research on Cancer; 1973. p.271.
  3. International Agency for Research on Cancer. Polynuclear aromatic compounds, Part 2 Carbon Blacks, mineral oils (lubricant base oils and derived products) and some nitroarenes. In: IARC Monographs on the evaluation of carcinogenic risks to humans). Lyon, France: International Agency for Research on Cancer; 1984. p.245.
  4. International Agency for Research on Cancer. Polynuclear aromatic compounds, Part 3 Industrial exposures in aluminium production, coal gasification, coke production, and iron and steel foundin. In IARC Nonographs on the evaluation of carcinogenic risks to humans Lyon, France: International Agency for Research on Cancer; 1984. p.219.
  5. International Agency for Research on Cancer. Polynuclear aromatic compounds, Part 4: Bitumens, coal-tars and derived products, shale-oils and soots. In IARC monographs on the evaluation of carcinogenic risks to humans. Lyon, France: International Agency for Research on Cancer; 1985. p.271.
  6. National Toxicology Program. 9th Report on carcinogens. Revised edition. U.S. Department of Health and Human Services, Public Health Service, Research Triangle Park, North Carolina: National Toxicology Program; 2001.
  7. WHO. Guideline for drinking-water quality Vol. 1 Recommendation. Geneva; 1984. p.67.
  8. Lioy PJ, Waldman JM, Greenberg AR. The total human environmental exposure study (THESS) to benzo(a)pyrene: Comparison of the inhalation and food pathways. Archives of Environmental Health. 1988; 43: 304-312. https://doi.org/10.1080/00039896.1988.10545954
  9. Acheson KJ, Campbell IT, Edholm OG, Miller DS, Stock MJ. The measurement of food and energy intake in man-an evaluation of some techniques. The American Journal of Clinical Nutrition. 1980; 33: 1147-1154. https://doi.org/10.1093/ajcn/33.5.1147
  10. Yamada Y, Hirata H, Fujimura K, Ohtsuji K, Tani Y, Shimbo S, Imai Y, Watanabe T, Moon C-S, Ikeda M. Disappearance of differences in nutritional intake across two local cultures in Japan: A comparison between Tokyo and Kyoto. The Tohoku Journal of Experimantal Medicine. 1996; 180: 1-15. https://doi.org/10.1620/tjem.180.1
  11. Moon C-S, Jo EM, Lee C-K, Kim JM, Hong YS, Son B-S, et al. Blood concentration of polycyclic aromatic hydrocarbons from non-occupational exposure in farming town near metropolitan Busan, Korea: Environmental tobacco smoke and roasted food intake as influential factors. Journal of Korean Society of Occupational and Environmental Hygiene. 2010; 20(2):.111-118.
  12. Nam H, Seo I, Shin H-S. Influence of roasting conditions on polycyclic aromatic hydrocarbon contents in ground coffee bean. Korean Journal of Food Science and Technology. 2009; 41(4): 362- 368.
  13. Rose M, White S, Macarthur R, Petch RG, Holland J, Damant AP. Single-laboratory validation of a GC/ MS method for the determination of 27 polycyclic aromatic hydrocarbons(PAHs) in oils and fats. Food Additives and Contaminants. 2007; 24(6): 635-651. https://doi.org/10.1080/02652030601135936
  14. Ding YS, Yan XJ, Jain RB, Lopp E, Tavakoli A, Polzin GM et al. Determination of 14 polycyclic aromatic hydrocarbons in mainstream smoke from U.S. brand and non-U.S. brand cigarettes. Environmental Science & Technology. 2006; 404: 1133-1138.
  15. Hu Y, Zhou Z, Xue X, Li X, Fu J, Cohen B et al. Sensitive biomarker of polycyclic aromatic hydrocarbons (PAHs): urinary 1-hydroxypyrene glucuronide in relation to smoking and low ambient levels of exposure. Biomarkers. 2006; 11: 306-318. https://doi.org/10.1080/13547500600626883
  16. Moon C-S and Paik JM. Dietary intake and body burden of cadmium and lead among Korean college students. Journal of Korean Society of Occupational and Environmental Hygiene. 2011; 21(1): 25-32.
  17. Gimmer G, Naujack KW, Dettbarn G. Gas chromatographic determination of polycyclic aromatic hydrocarbons, aza-arenens, aromatic amines in the particle and vapor phase of mainstream and side stream smoke of cigarettes. Toxicology Letters. 1987; 35: 117-124. https://doi.org/10.1016/0378-4274(87)90095-6
  18. Scherer G, Conze C, VonMeyerinck L, Sorsa M, Adlkofer F. Importance of exposure to gaseous and particulate phase components of tobacco smoke in active and passive smokers. International Archives of Occupupational and Environmental Health. 1990; 62: 459-466. https://doi.org/10.1007/BF00379064
  19. Lu H and Zhu L. Pollution patterns of polycyclic aromatic hydrocarbons in tobacco smoke. Journal of Hazardous Materials. 2007; A139: 193-198.
  20. Reinik M, Tame T, Roasto M, Junkam K, Tenno T, Kiis A. Polycyclic aromatic hydrocarbons (PAHs) in meat products and estimated PAH intake by children and the general population in Estonia. Food Additives and Contaminants. 2007; 24: 427-437.
  21. Ibez R, Agudo A, Berenguer A, Jakszyn P, Tormo MJ, Sanchz MJ, et al. Dietary intake of polycyclic aromatic hydrocarbons in a Spanish population. Journal of Food Protection. 2005; 68: 2190-2195. https://doi.org/10.4315/0362-028X-68.10.2190
  22. Suzuki K, Yoshinaga J. Inhalation and dietary exposure to polycyclic aromatic hydrocarbons and urinary 1-hydroxypyrene in non-smoking university students. International Archives of Occupupational and Environmental Health. 2007; 81: 115-121. https://doi.org/10.1007/s00420-007-0188-x
  23. Sinha R, Peters U, Cross AJ, Kulldorff M, Weissfeld JL, Pinsky PF et al. Meat, Meat cooking methods and preservation, and risk for colorectal adenoma. Cancer Research. 2005; 65: 8034-8041. https://doi.org/10.1158/0008-5472.CAN-04-3429
  24. Kazerouni N, Shnha R, Hsu C-H, Greenberg A, Rothman N. Analysis of 200 food items for benzo(a)pyrene and estimation of its intake in an epidemiologic study. Food Chemical Toxicology. 2001; 39: 423-436. https://doi.org/10.1016/S0278-6915(00)00158-7
  25. Phillips DH. Polycyclic aromatic hydrocarbons in the diet. Mutation research - Genetic toxicology and environmental mutagenesis. 1999; 443: 139-147. https://doi.org/10.1016/S1383-5742(99)00016-2
  26. Korean Food and Drug Administration. Benzo(a)pyrene Risk profile. In: A series of hazardous materials. Korean Food and Drug Administration; 2010.
  27. National Institute of Environmental Research. Analysis manual for environmental contaminants in biological samples. (11-1480523-000089-01). Incheon, Korea: National Institute of Environmental Research; 2006. p.220-248.
  28. Paik J-M, Moon C-S. Concentration of Fe, Cu, Zn in 24-hour Food Duplicate Samples: Quantitative Analysis by Inductively Coupled Plasma - Atomic Emission Spectrometry Journal of Environmental Health Sciences; 2007. 33: 397-402. https://doi.org/10.5668/JEHS.2007.33.5.397
  29. Moon C-S. Evaluation of Cd and Pb intake and exposure routes in some Korean women. Journal of Environmental Health Sciences; 2007. 33: 353-358. https://doi.org/10.5668/JEHS.2007.33.5.353
  30. Moon C-S, Paik J-M. Estimation of PCDDs/PCDFs intake for Korean children and their mothers through daily foods. Journal of Environmental Health Sciences; 2007. 33: 11-15. https://doi.org/10.5668/JEHS.2007.33.1.011