생물정신의학 (Korean Journal of Biological Psychiatry)

  • 제19권1호
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  • Pages.53-59
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  • 2012
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  • 1225-8709(pISSN)
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  • 2005-7571(eISSN)
대한생물정신의학회 (The Korean Society of Biological Psychiatry)
권호 표지

양극성 장애 환자의 자서전적 기억

Autobiographical Memory in Patients with Bipolar Disorder

  • 선자연 (연세대학교 의과대학 정신건강의학교실) ;
  • 하라연 (연세대학교 의과대학 정신건강의학교실) ;
  • 이수진 (연세대학교 의과대학 의학행동과학연구소) ;
  • 유빈 (건양대학교 의과대학 정신건강의학교실) ;
  • 하규섭 (분당서울대학교병원 정신건강의학과) ;
  • 조현상 (연세대학교 의과대학 정신건강의학교실)
  • Sun, Ja-Yeun (Department of Psychiatry, Yonsei University College of Medicine) ;
  • Ha, Ra-Yeon (Department of Psychiatry, Yonsei University College of Medicine) ;
  • Lee, Su-Jin (Institute of Behavioral Science in Medicine, Yonsei University College of Medicine) ;
  • Ryu, Vin (Department of Psychiatry, Konyang University College of Medicine) ;
  • Ha, Kyoo-Seob (Department of Psychiatry, Seoul National University Bundang Hospital) ;
  • Cho, Hyun-Sang (Department of Psychiatry, Yonsei University College of Medicine)
  • 투고 : 2011.10.05
  • 심사 : 2011.11.10
  • 발행 : 2012.02.29
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초록

Objectives : Autobiographical memory (ABM) is a special type of episodic memory, containing events that have occurred in a personal life. Overgeneral tendency of ABM refers to the retrieval of memory with only general and categorical descriptions rather than specific events. ABM specificity in depression and posttraumatic stress disorder is a robust finding with relation to cognitive vulnerability, affect regulation, problem-solving ability. It is also implicated in bipolar disorder with frequent relapses. In this study, we investigated whether ABM specificity was related to manic or euthymic mood states in patients with bipolar disorder. Methods : Forty bipolar patients with manic and euthymic episodes and 25 healthy controls participated in this study. Prompted by 5 positively and 5 negatively valenced emotional cue words, each participant was instructed to recall positive or negative memories and describe them in detail. The One-way ANOVA was used to compare ABM scores and post-hoc analyses were done. Results : Comapred to the healthy persons, the bipolar patients reported significantly more general than specific negative memories in both manic and euthymic episodes (p = 0.003). However, there was no significant difference between manic and euthymic patients (p = 0.074). Conclusions : These results suggest that overgeneral tendency of negative ABM may be a trait abnormality in bipolar disorder. Moreover, this phenomenon might be related to underlying cognitive deficits or affect regulation irrespective of the mood state.

키워드

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