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The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Antimicrobial Peptides as Natural Antibiotic Materials

새로운 천연 항생물질로서의 항균 펩타이드

  • Received : 2012.02.06
  • Accepted : 2012.02.25
  • Published : 2012.02.29
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Abstract

Antimicrobial peptides are widely used in various organisms as a defense system against infection. The peptides are lethal towards bacteria and fungi, however have minimal toxicity in mammalian and plant cells. In this aspect, it is considered that antimicrobial peptides are new alternative materials for defensing against microbial infection. Here, we describe overall characteristics of antimicrobial peptides based on the mechanism of action, classification of the peptides, report detection/screening methods and chemical/biological production. It is expected that understanding of innate immune system based on antimicrobial peptides tends to develop novel natural antimicrobial agents, which might be applied for defensing pathogenic microorganisms resistant to conventional antibiotics.

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References

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