Radiation Oncology Journal

  • 제30권1호
  • /
  • Pages.36-42
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  • 2012
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  • 2234-1900(pISSN)
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  • 2234-3156(eISSN)
대한방사선종양학회 (The Korean Society for Radiation Oncology)
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Radial displacement of clinical target volume in node negative head and neck cancer

  • Jeon, Wan (Department of Radiation Oncology, Seoul National University College of Medicine) ;
  • Wu, Hong-Gyun (Department of Radiation Oncology, Seoul National University College of Medicine) ;
  • Song, Sang-Hyuk (Department of Radiation Oncology, Seoul National University College of Medicine) ;
  • Kim, Jung-In (Department of Radiation Oncology, Kangbuk Samsung Hospital)
  • 투고 : 2012.03.02
  • 심사 : 2012.03.22
  • 발행 : 2012.03.31
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초록

Purpose: To evaluate the radial displacement of clinical target volume in the patients with node negative head and neck (H&N) cancer and to quantify the relative positional changes compared to that of normal healthy volunteers. Materials and Methods: Three node-negative H&N cancer patients and five healthy volunteers were enrolled in this study. For setup accuracy, neck thermoplastic masks and laser alignment were used in each of the acquired computed tomography (CT) images. Both groups had total three sequential CT images in every two weeks. The lymph node (LN) level of the neck was delineated based on the Radiation Therapy Oncology Group (RTOG) consensus guideline by one physician. We use the second cervical vertebra body as a reference point to match each CT image set. Each of the sequential CT images and delineated neck LN levels were fused with the primary image, then maximal radial displacement was measured at 1.5 cm intervals from skull base (SB) to caudal margin of LN level V, and the volume differences at each node level were quantified. Results: The mean radial displacements were 2.26 (${\pm}1.03$) mm in the control group and 3.05 (${\pm}1.97$) in the H&N cancer patients. There was a statistically significant difference between the groups in terms of the mean radial displacement (p = 0.03). In addition, the mean radial displacement increased with the distance from SB. As for the mean volume differences, there was no statistical significance between the two groups. Conclusion: This study suggests that a more generous radial margin should be applied to the lower part of the neck LN for better clinical target coverage and dose delivery.

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참고문헌

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피인용 문헌

  1. Vision 20/20: Perspectives on automated image segmentation for radiotherapy vol.41, pp.5, 2014, https://doi.org/10.1118/1.4871620
  2. Setup uncertainties for inter-fractional head and neck cancer in radiotherapy vol.7, pp.29, 2012, https://doi.org/10.18632/oncotarget.9748
  3. Patient positioning in head and neck cancer : Setup variations and safety margins in helical tomotherapy vol.194, pp.5, 2018, https://doi.org/10.1007/s00066-018-1265-7
  4. Positional uncertainties of cervical and upper thoracic spine in stereotactic body radiotherapy with thermoplastic mask immobilization vol.36, pp.2, 2012, https://doi.org/10.3857/roj.2017.00591
  5. Comparison of Intrafractional Motion in Head and Neck Cancer Between Two Immobilization Methods During Stereotactic Ablative Radiation Therapy by CyberKnife vol.12, pp.None, 2012, https://doi.org/10.2147/cmar.s283746