Tuberculosis and Respiratory Diseases

  • 제72권1호
  • /
  • Pages.55-58
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  • 2012
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
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완치된 결핵환자에서 발생한 Mycobacterium szulgai 폐질환 1예

A Case of Mycobacterium szulgai Lung Disease in Patient with Healed Tuberculosis

  • 이은정 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실) ;
  • 박지영 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실) ;
  • 김은영 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실) ;
  • 최재호 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실) ;
  • 김현수 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실) ;
  • 정상완 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실) ;
  • 유지홍 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실) ;
  • 최천웅 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실) ;
  • 김교영 (경희대학교 의과대학 강동경희대학교병원 병리학교실) ;
  • 이종후 (제주대학교 의학전문대학원 제주대병원 호흡기내과학교실) ;
  • 김이형 (경희대학교 의과대학 강동경희대학교병원 호흡기내과학교실)
  • Lee, Eun-Jung (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Park, Ji-Young (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Kim, Eun-Young (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Choi, Jae-Ho (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Kim, Hyun-Soo (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Chung, Sang-Wan (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Yoo, Jee-Hong (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Choi, Cheon-Woong (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Kim, Gou-Young (Department of Pathology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine) ;
  • Lee, Jong-Hoo (Department of Pulmonary and Critical Care Medicine, Jeju National University Hospital, Jeju National University School of Medicine) ;
  • Kim, Yee-Hyung (Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine)
  • 투고 : 2011.07.22
  • 심사 : 2011.08.19
  • 발행 : 2012.01.30
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초록

Mycobacterium szulgai is a rare nontuberculous mycobacterium found in Korea. It is an opportunistic pathogen and is usually isolated from patients with a history of alcoholism, chronic pulmonary disease, or an immunocompromising condition. We present here a case of M. szulgai isolated from a patient with a history of pulmonary tuberculosis. A 54-year-old man was admitted with dyspnea and febrile sensation. He had a history of pulmonary tuberculosis which occurred 30 years earlier and treatment with anti-tuberculosis medication. His chest computed tomography scan showed cavitary consolidation in both upper lungs. A sputum acid-fast bacilli (AFB) smear was positive and anti-tuberculous medication was started. However, a polymerase chain reaction for mycobacterium tuberculosis was negative and anti-tuberculous medication was stopped. M. szulgai was isolated on 3 separate sputum and bronchial wash fluid AFB cultures. He was treated with clarithromycin, rifampicin, and ethambutol. After 1 month, a sputum AFB smear and culture became negative and no additional M. szulgai were isolated during a 16-month treatment.

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참고문헌

  1. Park YS, Lee CH, Lee SM, Yang SC, Yoo CG, Kim YW, et al. Rapid increase of non-tuberculous mycobacterial lung diseases at a tertiary referral hospital in South Korea. Int J Tuberc Lung Dis 2010;14:1069-71.
  2. van Ingen J, Boeree MJ, de Lange WC, de Haas PE, Dekhuijzen PN, van Soolingen D. Clinical relevance of Mycobacterium szulgai in the Netherlands. Clin Infect Dis 2008;46:1200-5.
  3. Koh WJ, Kwon OJ, Lee KS. Diagnosis and treatment of nontuberculous Mycobacterial pulmonary diseases: a Korean perspective. J Korean Med Sci 2005;20: 913-25.
  4. Marks J, Jenkins PA, Tsukamura M. Mycobacterium szulgai--a new pathogen. Tubercle 1972;53:210-4.
  5. Benator DA, Kan V, Gordin FM. Mycobacterium szulgai infection of the lung: case report and review of an unusual pathogen. Am J Med Sci 1997;313:346-51.
  6. Maloney JM, Gregg CR, Stephens DS, Manian FA, Rimland D. Infections caused by Mycobacterium szulgai in humans. Rev Infect Dis 1987;9:1120-6.
  7. Shenai S, Rodrigues C, Mehta A. Time to identify and define non-tuberculous mycobacteria in a tuberculosis- endemic region. Int J Tuberc Lung Dis 2010;14: 1001-8.
  8. Alvarez-Uria G. Lung disease caused by nontuberculous mycobacteria. Curr Opin Pulm Med 2010;16: 251-6.
  9. Koh WJ, Kwon OJ, Yu CM, Jeon KM, Suh GY, Chung MP, et al. Recovery rate of nontuberculous Mycobacteria from acid-fast-bacilli smear-positive sputum specimens. Tuberc Respir Dis 2003;54:22-32.
  10. Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med 2007;175:367-416.
  11. Kim JH, Suh JT, Park SY, Lee HJ, Lee WI. Clinical evaluation of 10 cases of nontuberculous Mycobacteria isolated from sputum. Korean J Lab Med 2004;24:49-52.