Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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The Antifungal Activity of Bee Venom against Dermatophytes

  • Yu, A-Reum (Department of Medical Biotechnology, SoonChunHyang University) ;
  • Kim, Jum-Ji (Department of Medical Biotechnology, SoonChunHyang University) ;
  • Park, Gil-Sun (Department of Medical Biotechnology, SoonChunHyang University) ;
  • Oh, Su-Mi (DongSung Pharm. Co., Ltd.) ;
  • Han, Chung-Sub (DongSung Pharm. Co., Ltd.) ;
  • Lee, Mi-Young (Department of Medical Biotechnology, SoonChunHyang University)
  • Received : 2011.09.27
  • Accepted : 2012.02.21
  • Published : 2012.03.31
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Abstract

The antifungal activities of the bee venom against Trichophyton mentagrophytes and Trichophyton rubrum were determined by using modified broth dilution assay. The most common dermatophytes, named T. mentagrophytes and T. rubrum, were known to cause a variety of cutaneous infections in humans and animals. The bee venom exhibited prominent antifungal activities against the two dermatophytes tested in this investigation. Moreover, the antifungal activities of the bee venom were much stronger than that of fluconazole, one of the commercial antifungal drugs used in the treatment and prevention of superficial and systemic fungal infections. The result suggests that bee venom could be developed as a natural antifungal drug.

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