Biomaterials Research (생체재료학회지)

Korean Society for Biomaterials (한국생체재료학회)
권호 표지

Comparative Study of Bone Regeneration in Rabbit Calvarial Defect Following Implantation with Demineralized Bone Matrix Gel, Bovine Bone, Synthetic Hydroxyapatite

토끼 두개골 모델에서 탈회동종골, 탈회우골, 및 합성 Hydroxyapatite의 골재생 비교연구

  • Zhang, Ming-Lan (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry) ;
  • Unursaikhan, Otgonbayar (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry) ;
  • Yang, Cheryl (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry) ;
  • Lee, Jung-Seok (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry) ;
  • Jung, Ui-Won (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry) ;
  • Kim, Chang-Sung (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry) ;
  • Choi, Seong-Ho (Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry)
  • ;
  • ;
  • 양혜주 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 이중석 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 정의원 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 김창성 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 최성호 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소)
  • Published : 2012.12.01
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Abstract

The purpose of this study was to compare bone regenerative effects of allograft, xenograft, and alloplast bone substitutes in rabbit calvarial defects. 14 male New Zealand rabbits were used. Four defects with a diameter of 8 mm were created on each animal. Demineralized bone matrix (DBM) gel, bovine bone (BB) and hydroxyapatite (HA) were used as the three test groups, while the control group was left unfilled. The animals were sacrificed after 2 and 8 weeks of healing. All experimental groups at 8 weeks showed statistically significant differences in new bone formation compared 2 weeks. Residual biomaterials in sites received DBM gel decreased compared to the sites received BB and HA. Within the limits of this study, there were no significant differences in bone regeneration between the sites received DBM gel, BB, and HA.

Keywords

References

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