후두 편평상피암종의 림프절 피막외 침범에 대한 FDG PET/CT 영상의 유용성

Utility of FDG PET/CT Scans on Extracapsular Spread of Squamous Cell Carcinoma in the Larynx

  • 주영훈 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 유이령 (가톨릭대학교 의과대학 핵의학과학교실) ;
  • 조광재 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 송지남 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 유동준 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 이호석 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 김민식 (가톨릭대학교 의과대학 이비인후과학교실)
  • Joo, Young-Hoon (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Yoo, Ie-Ryung (Department of Nuclear Medicine, College of Medicine, The Catholic University of Korea) ;
  • Cho, Kwang-Jae (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Song, Jee-Nam (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Yoo, Dong-Joon (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Lee, Ho-Suk (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea) ;
  • Kim, Min-Sik (Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea)
  • 투고 : 2012.11.01
  • 심사 : 2012.11.12
  • 발행 : 2012.11.30

초록

Backgrounds : To evaluated the use of FDG PET/CT for the identification of extracapsular spread(ECS) with histologic correlation in laryngeal cancer. Methods : We reviewed 79 medical records of patients who underwent of FDG PET/CT for laryngeal cancer before surgery. Results : ECS was present in 41.9%(18/43) dissected necks and in 34.5%(20/58) dissected cervical levels. There was a significant difference in the SUVmax between cervical lymph nodes with ECS and without ECS($6.39{\pm}4.53$ vs. $1.19{\pm}1.64$, p<0.001). The cut-off value for the SUVmax for differentiating with ECS from without ECS was 2.8 with the sensitivity of 85.7% and the specificity of 85.6%. Conclusion : The median SUVmax cut-off values of FDG PET/CT higher than 2.8 was associated with greater risk cervical lymph node metastasis with ECS in patients with laryngeal cancer.

키워드

참고문헌

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