Short-term Prognosis according to Time of Treatment of Patients with Acute Cerebral Infarction : Measurement by NIHSS

급성기 뇌경색환자의 치료시기에 따른 단기 예후 평가 : NIHSS를 이용한 후향적 연구

  • Park, Seung Chan (Department of Internal Medicine, Pusan National University Oriental Medicine Hospital) ;
  • Cho, Seung Mo (Pusan National University School of Korean Medicine) ;
  • Kim, Do Gyoung (Department of Internal Medicine, Dong Eui Medical Center) ;
  • Lim, Chi Yeon (Department of Medicine, Medical School, Dongguk University) ;
  • Lee, Jae Wook (Department of Internal Medicine, Dong Eui Medical Center) ;
  • Hong, Jin Woo (Pusan National University School of Korean Medicine) ;
  • Lee, In (Pusan National University School of Korean Medicine) ;
  • Lee, In Sun (Department of Rehabilitation Medicine, Dong Eui Medical Center) ;
  • Kim, Young Kyun (Department of Internal Medicine, Dong Eui Medical Center) ;
  • Kwon, Jung Nam (Pusan National University School of Korean Medicine)
  • 박승찬 (부산대학교 한방병원 한방내과) ;
  • 조승모 (부산대학교 한의학전문대학원) ;
  • 김도경 (동의의료원 한방내과) ;
  • 임지연 (동국대학교 의과대학 의학과) ;
  • 이재욱 (동의의료원 한방내과) ;
  • 홍진우 (부산대학교 한의학전문대학원) ;
  • 이인 (부산대학교 한의학전문대학원) ;
  • 이인선 (동의의료원 한방재활의학과) ;
  • 김영균 (동의의료원 한방내과) ;
  • 권정남 (부산대학교 한의학전문대학원)
  • Received : 2012.09.10
  • Accepted : 2012.10.22
  • Published : 2012.12.25

Abstract

This study was done to examine the prognosis according to onset and duration of treatment in acute ischemic cerebral infarction patients. We analysed NIHSS(National Institutes of Health Stroke Scale) score of acute ischemic cerebral infarction patients who visited department of Internal Korean Medicine, one medical center in Busan from January to December 2009. We divided patients into two groups by the initial time of treatment. Group A is admitted within 7 days, Group B is admitted from 7 to 14 days. We used NIHSS for functional recovery after 3 weeks later from admission day, and analyzed prognostic factor by analysis of covariance. All patients showed statistically significant improvement after 1week, 2weeks, 3weeks from admission, and between 1st week and 2nd week. However, there was no significant difference between 2nd week and 3rd week. NIHSS recovery score after 3weeks were analysed according to the timing of treatment. There was a statistically significant difference between two groups. The percentage of aggravated patients showed no statistically significant difference between the two groups. This study suggests that earlier admission care has an effect on functional recovery of patients with acute ischemic cerebral infarction. Further research on the large scale and long-term follow up is required.

Keywords

References

  1. 통계청. 2010년 사망원인통계 결과. pp 1-52, 2001.
  2. 정한영, 권희규. 뇌졸중 환자의 재활치료 시점에서의 평가와 기능적 회복에 관한 연구. 대한재활의학회지 15(4):398-404, 1991.
  3. 최은정, 이원철. 급성기 뇌졸중 환자의 상태와 기능회복도와의 상관관계. 한의대 연구소 논문집 6(2):167-190, 1998.
  4. 최은정, 신길조, 이원철. 뇌졸중 환자의 예후를 결정하는 요인에 대한 연구. 대한한방성인병학회지 3(1):101-125, 1997.
  5. Jorgensen, H.S., Nakayama, H., Reith, J., Raaschou, H.O., Olsen, T.S. Factors Delaying Hospital Admission in Acute Stroke: The Copenhagen Stroke Study. Neurol 47(2):383-387, 1996. https://doi.org/10.1212/WNL.47.2.383
  6. Kay, R., Woo, J., Poon, W.S. Hospital Arrival Time after Onset of Stroke. J Neurol Neurosurg Psychiatry 55: 973-974, 1992. https://doi.org/10.1136/jnnp.55.10.973
  7. 정기영, 정진상, 신경식, 이훈복, 김종홍. 급성뇌졸중환자의 응급실도착 지연요인에 관한 연구 -대전 및 인근 지역 거주환자를 중심으로-. 대한신경과학회지 3(2):207-213, 1995.
  8. Albert, M.J., Bertels, C., Dawson, D.V. An Analysis of Time of Presentation after Stroke. JAMA 263(1):65-68, 1990. https://doi.org/10.1001/jama.1990.03440010063031
  9. 조용진, 박병주, 윤병우, 정재면, 조진환. 서울대학교병원 응급실을 방문하였던 급성 뇌졸중 환자들의 도착시간 관련요인에 관한 연구. 대한신경과학회지 14(3):696-703, 1996.
  10. Anderson TP, Bourestorn N, Greenberg FR, Hildyard VG. Predictive Factors in Stroke Rehabilitation. Arch Phys Med Rehabil 55(12):545-553, 1974.
  11. 김승은, 김도형, 고창남, 김용석, 박동원, 이경섭. 한방병원에 입원한 뇌졸중 환자의 역학적 동향에 대한 임상적 관찰. 대한한의학회지 21(4):104-111, 2000.
  12. Lyden, P., Brott, T., Tilley, B., Welch, K.M., Mascha, E.J., Levine, S., Haley, E.C., Grotta, J., Marler, J. Improved Reliability of the NIH Stroke Scale Using Video Training. NINDS TPA Stroke Study Group. Stroke. 25(11):2220-2226, 1994. https://doi.org/10.1161/01.STR.25.11.2220
  13. Lyden P, Lu M, Jackson C, Marler J, Kothari R, Brott T, Zivin, J. Underlying Structure of the National Institutes of Health Stroke Scale: Results of a Factor Analysis. NINDS tPA Stroke Trial Investigators. Stroke 30(11):2347-2354, 1999. https://doi.org/10.1161/01.STR.30.11.2347
  14. Goldstein, L.B., Bertels, C., Davis, J.N. Interrater Reliability of the NIH Stroke Scale. Arch Neurol 46(6):660-662, 1989. https://doi.org/10.1001/archneur.1989.00520420080026
  15. Muir, K.W., Weir, C.J., Murray, G.D., Povey, C., Lees, K.R. Comparison of Neurological Scales and Scoriong Systems for Acute Stroke Prognosis. Stroke 27(10):1817-1820, 1996. https://doi.org/10.1161/01.STR.27.10.1817
  16. 이상호, 김성수, 신현대. 한글판 NIH Stroke Scale의 신뢰도평가. 한방재활의학과학회지 11(3):1-12, 2001.
  17. 노진환, 최동준, 문상관, 조기호, 김영석, 배형섭, 이경섭. 한방병원에 입원한 중풍환자의 기능회복도 평가:MBI와 NIH Stroke Scale이용. 한방성인병학회지 5(1):40-49, 1999.
  18. 김영지, 김미영, 이승엽, 최원우, 박주영, 권승원, 정우상, 문상관, 조기호, 김영석, 박성욱, 박정미, 고창남, 배형석, 나병조. 한방병원에 입원한 뇌경색 환자의 기능회복과 관련된 특성에 대한 연구. 대한한방내과학회지 30(4):719-731, 2009.
  19. 고성규, 오희라. 급성기 뇌졸중 환자의 기능회복도에 대한 임상적 고찰: MBI, MAS를 이용하여. 한방성인병학회지 3(1):206-230, 1997.
  20. 고성규, 조기호, 김영석, 배형섭, 이경섭. 중풍환자의 기능회복도에 대한 임상적 고찰. 한.중 중풍병 학술대회 참가논문집 pp 443-487, 1994.
  21. Teal, P.A., Pessin, M.S. Hemorrhagic Transformation: the Spectrum of Ischemia-Related Brain Hemorrhage. Neurosurg Clin N Am 3(3):601-610, 1992.
  22. Cardiogenic Brain Embolism: the Second Report of the Cerebral Embolism Task Force. Arch Neurol 46(7):727-743, 1989. https://doi.org/10.1001/archneur.1989.00520430021013