Mycobiology

  • 제40권1호
  • /
  • Pages.42-46
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  • 2012
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  • 1229-8093(pISSN)
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  • 2092-9323(eISSN)
한국균학회 (The Korean Society of Mycology)
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Isolation, Identification and Characterization of a Antidementia Acetylcholinesterase Inhibitor-Producing $Yarrowia$ $lipolytica$ S-3

  • Kang, Min-Gu (Department of Life Science and Genetic Engineering, PaiChai University) ;
  • Yoon, Min-Ho (Department of Bio-Environmental Chemistry, Chungnam National University) ;
  • Choi, Young-Jun (Microbial and Enzymatic Technology Group, Bioprocess Platform, Biotechnology Research Institite, National Research Council of Canada) ;
  • Lee, Jong-Soo (Department of Life Science and Genetic Engineering, PaiChai University)
  • 투고 : 2012.02.16
  • 심사 : 2012.03.09
  • 발행 : 2012.03.31
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초록

This report describes the isolation and identification of a potent acetylcholinesterase (AChE) inhibitor-producing yeasts. Of 731 species of yeast strain, the S-3 strain was selected as a potent producer of AChE inhibitor. The selected S-3 strain was investigated for its microbiological characteristics. The S-3 strain was found to be short-oval yeast that did not form an ascospore. The strain formed a pseudomycelium and grew in yeast malt medium containing 50% glucose and 10% ethanol. Finally, the S-3 strain was identified by its physiological characteristics and 26S ribosomal DNA sequences as $Yarrowia$ $lipolytica$ S-3.

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