참고문헌
- Bahrami, A. R., M. M. Matin, and P. W. Andrews. 2005. The CDK inhibitor p27 enhances neural differentiation in pluripotent NTERA2 human EC cells, but does not permit differentiation of 2102Ep nullipotent human EC cells. Mech. Dev. 122: 1034-1042. https://doi.org/10.1016/j.mod.2005.04.011
- Baldassarre, G., M. V. Barone, B. Belleti, C. Sandomenico, P. Bruni, S. Spiezia, et al. 1999. Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation. Oncogene 18: 6241-6251. https://doi.org/10.1038/sj.onc.1203031
- Baldassarre, G., A. Boccia, P. Bruni, C. Sandomenico, M. V. Barone, S. Pepe, et al. 2000. Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. Cell Growth Differ. 11: 517-526.
- Boonen, G. J. J. C., B. A. van Oirschot, A. van Diepen, W. J. M. Mackus, L. F. Verdonck, G. Rijksen, et al. 1999. Cyclin D3 regulates proliferation and apoptosis of leukemic T cell lines. J. Biol. Chem. 274: 34676-34682. https://doi.org/10.1074/jbc.274.49.34676
-
Bryja, V., L. Cajanek, J. Pachernik, A. C. Hall, V. Horvath, P. Dvorak, and A. Hampl. 2005. Abnormal development of mouse embryoid bodies lacking
$p27^{Kip}$ cell cycle regulator. Stem Cells 23: 965-974. https://doi.org/10.1634/stemcells.2004-0174 - Bryja, V., J. Pachernik, K. Soucek, V. Horvath, P. Dvorak, and A. Hampl. 2004. Increased apoptosis in differentiating p27-deficient embryonic stem cells. Cell. Mol. Life Sci. 61: 1384-1400. https://doi.org/10.1007/s00018-004-4081-4
- Constantinescu, D., H. L. Gray, P. J. Sammak, G. P. Schatten, and A. B. Csoka. 2006. Lamin A/C expression is a marker of mouse and human embryonic stem cell differentiation. Stem Cells 24: 177-185. https://doi.org/10.1634/stemcells.2004-0159
- Egozi, D., M. Shapira, G. Paor, O. Ben-Izhak, K. Skorecki, and D. D. Hershko. 2007. Regulation of the cell cycle inhibitor p27 and its ubiquitin ligase Skp2 in differentiation of human embryonic stem cells. FASEB J. 21: 2807-2817. https://doi.org/10.1096/fj.06-7758com
- Glozak, M. A. and M. B. Rogers. 2001. Retinoic acid- and bone morphogenetic protein 4-induced apoptosis in P19 embryonal carcinoma cells requires p27. Exp. Cell Res. 268: 128-138. https://doi.org/10.1006/excr.2001.5281
- Grana, X. and F. P. Reddy. 1995. Cell cycle control in mammalian cells: Role of cyclins, cyclin-dependent kinases (CDK), growth suppressor genes, and inhibitors (CKIs). Oncogene 11: 211-219.
- Hiromura, K., J. W. Pippin, M. L Fero, J. M. Roberts, and S. J. Shankland. 1999. Modulation of apoptosis by the cyclindependent kinase inhibitor p27Kip1. J. Clin. Invest. 103: 597-604. https://doi.org/10.1172/JCI5461
- Joza, N., S. A. Susin, E. Daugas, W. L. Stanford, S. K. Cho, C. Y. J. Li, et al. 2001. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 410: 549-554. https://doi.org/10.1038/35069004
-
Kenneth, J. L. and D. S. Thomas. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the
$2^{-{\Delta}{\Delta}C_T}$ method. Methods 25: 402-408. https://doi.org/10.1006/meth.2001.1262 - Lloyd, R. V., L. A. Erickson, L. Jin, E. Kulig, X. Qian, J. C. Cheville, et al. 1998. p27kip1: A multifunctional cyclindependent kinase inhibitor with prognostic significance in human cancers. Am. J. Pathol. 154: 313-323.
- Morgan, D. O. 1995. Principles of Cdk regulation. Nature 374: 131-134. https://doi.org/10.1038/374131a0
- Philipp-Staheli, J., S. R. Payne, and C. J. Kemp. 2001. p27Kip1: Regulation and function of a haplo-insufficient tumor suppressor and its misregulation in cancer. Exp. Cell Res. 264: 148-168. https://doi.org/10.1006/excr.2000.5143
- Reed, S. I., E. Bailly, V. Dulic, L. Hengst, D. Resnitzky, and J. Slingerland. 1994. G1 control in mammalian cells. J. Cell Sci. Suppl. 18: 69-73.
- Savatier, P., H. Lapillonne, L. A. van Grunsven, B. B. Rudkin, and J. Samarut. 1995. Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Oncogene 12: 309-322.
- Sherr, C. J. 1993. Mammalian G1 cyclins. Cell 48: 981-983.
- Sherr, C. J. and J. M. Roberts, 1995. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9: 1149-1163. https://doi.org/10.1101/gad.9.10.1149