Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthesis and Antibacterial Activity of Novel 2-Oxo-pyrrolidinyl Oxazolidinones

  • Bhattarai, Deepak (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology) ;
  • Lee, Sun-Hee (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology) ;
  • Kim, Hyeong-Kyu (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology) ;
  • Kang, Soon-Bang (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology) ;
  • Pae, Ae-Nim (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology) ;
  • Kim, Eunice Eun-Kyeong (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology) ;
  • Oh, Taeg-Won (Department of Microbiology and the Brain Korea 21 Project for the Medical Sciences, Yonsei University College of Medicine) ;
  • Cho, Sang-Nae (Department of Microbiology and the Brain Korea 21 Project for the Medical Sciences, Yonsei University College of Medicine) ;
  • Keum, Gyo-Chang (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology)
  • Received : 2012.01.25
  • Accepted : 2012.01.30
  • Published : 2012.04.20
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Abstract

Novel antibacterial oxazolidinones bearing pyrrolidinone ring system at the C-5 side chain were synthesized and their in vitro antibacterial activities were evaluated. Most of the synthesized oxazolidinones showed good antibacterial activity against the Gram-positive and Gram-negative bacteria tested.

Keywords

References

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