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멜라토닌의 특성에 대한 이론적 연구

Theoretical Study for the Characteristics of Melatonin

  • 김동엽 (영남이공대학 화장품.화공학부) ;
  • 정맹준 (경북대학교 나노소재공학부) ;
  • 이철재 (영남이공대학 화장품.화공학부)
  • Kim, Dong-Yeub (School of Chemical Industry, Yeungnam College of Science & Technology) ;
  • Jung, Maeng-Joon (Department of Chemical Engineering, Kyungpook National University) ;
  • Lee, Chul-Jae (School of Chemical Industry, Yeungnam College of Science & Technology)
  • 투고 : 2012.04.18
  • 심사 : 2012.05.25
  • 발행 : 2012.05.31

초록

Melatonin has been studied as a potential treatment of cancer, immune disorders, cardiovascular diseases, depression, seasonal affective disorder (SAD), circadian rhythm sleep disorders, sexual dysfunction and some forms of insomnia. Prolonged release melatonin has shown good results in treating insomnia in older adults. It may ameliorate circadian misalignment and SAD. Basic research indicates that melatonin may play a significant role in modulating the effects of drugs of abuse such as cocaine. A 2004 review found that melatonin significantly increased total sleep time in people suffering from sleep restriction. Therefore, in this study, in order to explain characteristics of melatonin, total energy, net charge, vibrational mode of melatonin are calculated by PM3 methods of HyperCam 6.0.

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