Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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Surface characteristics and osteoblastic cell response of alkali-and heat-treated titanium-8tantalum-3niobium alloy

  • Lee, Bo-Ah (Department of Periodontology, Dental Research Institute, Chonnam National University School of Dentistry) ;
  • Kang, Choong-Hee (Department of Prosthodontics, Chonnam National University School of Dentistry) ;
  • Vang, Mong-Sook (Department of Prosthodontics, Chonnam National University School of Dentistry) ;
  • Jung, Young-Suk (Department of Periodontology, Dental Research Institute, Chonnam National University School of Dentistry) ;
  • Piao, Xing Hui (Department of Periodontology, Dental Research Institute, Chonnam National University School of Dentistry) ;
  • Kim, Ok-Su (Department of Periodontology, Dental Research Institute, Chonnam National University School of Dentistry) ;
  • Chung, Hyun-Ju (Department of Periodontology, Dental Research Institute, Chonnam National University School of Dentistry) ;
  • Kim, Young-Joon (Department of Periodontology, Dental Research Institute, Chonnam National University School of Dentistry)
  • Received : 2012.11.09
  • Accepted : 2012.11.13
  • Published : 2012.12.31
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Abstract

Purpose: The aim of the present study was to evaluate the biological response of alkali- and heat-treated titanium-8tantalum-3niobium surfaces by cell proliferation and alkaline phosphatase (ALP) activity analysis. Methods: Commercial pure titanium (group cp-Ti) and alkali- and heat-treated titanium-8tantalum-3niobium (group AHT) disks were prepared. The surface properties were evaluated using scanning electron microscopy, energy dispersed spectroscopy and X-ray photoelectron spectroscopy (XPS). The surface roughness was evaluated by atomic force microscopy and a profilometer. The contact angle and surface energy were also analyzed. The biological response of fetal rat calvarial cells on group AHT was assessed by cell proliferation and ALP activity. Results: Group AHT showed a flake-like morphology microprofile and dense structure. XPS analysis of group AHT showed an increased amount of oxygen in the basic hydroxyl residue of titanium hydroxide groups compared with group cp-Ti. The surface roughness (Ra) measured by a profilometer showed no significant difference (P>0.05). Group AHT showed a lower contact angle and higher surface energy than group cp-Ti. Cell proliferation on group AHT surfaces was significantly higher than on group cp-Ti surfaces (P<0.05). In comparison to group cp-Ti, group AHT enhanced ALP activity (P<0.05). Conclusions: These results suggest that group AHT stimulates osteoblast differentiation.

Keywords

References

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