Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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A Case of Adrenocortical Carcinoma Secreting Cortisol and Aldosterone

코티졸, 알도스테론을 동시에 분비하는 부신피질암 1예

  • Ha, Jiyoon (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Min Kyung (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Cha, Yoon Jin (Department of Pathology, Yonsei University College of Medicine) ;
  • Kim, Seung Kyu (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Yun, Gi Young (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Rhee, Kwangwon (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Joon Seong (Department of Surgery, Yonsei University College of Medicine) ;
  • Cho, Eun-Suk (Department of Radiology, Yonsei University College of Medicine) ;
  • Ahn, Chul Woo (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Jong Suk (Department of Internal Medicine, Yonsei University College of Medicine)
  • 하지윤 (연세대학교 의과대학 내과학교실) ;
  • 김민경 (연세대학교 의과대학 내과학교실) ;
  • 차윤진 (연세대학교 의과대학 병리학교실) ;
  • 김승규 (연세대학교 의과대학 내과학교실) ;
  • 윤지영 (연세대학교 의과대학 내과학교실) ;
  • 이광원 (연세대학교 의과대학 내과학교실) ;
  • 박준성 (연세대학교 의과대학 외과학교실) ;
  • 조은석 (연세대학교 의과대학 영상의학과학교실) ;
  • 안철우 (연세대학교 의과대학 내과학교실) ;
  • 박종숙 (연세대학교 의과대학 내과학교실)
  • Received : 2012.08.17
  • Accepted : 2012.09.26
  • Published : 2012.12.31
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Abstract

Adrenocortical carcinomas are rare and frequently aggressive tumors that may be functional (hormone-secreting) and may cause Cushing's syndrome or virilization, or non-functional and manifest as an abdominal mass. This paper reports the case of a 77-year-old woman with cortisol- and aldosterone-secreting adrenal carcinoma. The patient complained of general weakness, a moon face, and weight gain. She also had hypokalemia and hypertension. Her endocrinological data showed excessive aldosterone production and non-suppressible cortisol production in a low-dose dexamethasone suppresion test. Her abdominal CT showed a right adrenal mass. She underwent right adrenalectomy, and her histology revealed the presence of adrenocortical carcinoma. After adrenalectomy, her hypokalemia returned to normal and she is being treated with hydrocortisone.

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