Korean Journal of Plant Resources (한국자원식물학회지)

The Plant Resources Society of Korea (한국자원식물학회)
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Screening for Anti-diabetic Effects of Prescribed Korean Traditional Medicines

  • Shin, Seon Mi (Department of Oriental Internal Medicine, Semyung University) ;
  • Jeong, Yong Joon (Department of Life Science, Gachon University) ;
  • Park, Dae Won (Department of Life Science, Gachon University) ;
  • Ko, Heung (Department of Oriental Internal Medicine, Semyung University) ;
  • Kim, Gi Tae (Department of Oriental Internal Medicine, Semyung University) ;
  • Kim, Ee-Hwa (Department of Meridian & Acupoint, Semyung University) ;
  • Kim, Taeseong (Department of Herbal Medicine Resource, Kangwon National University) ;
  • Sohn, Eun-Hwa (Department of Herbal Medicine Resource, Kangwon National University) ;
  • Kwon, Jung-Eun (Department of Life Science, Gachon University) ;
  • Koo, Hyun Jung (Department of Life Science, Gachon University) ;
  • Kang, Se Chan (Department of Life Science, Gachon University)
  • Received : 2012.12.07
  • Accepted : 2012.12.12
  • Published : 2012.12.31
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Abstract

Herb extracts commercially used in Korea were screened for PPAR-${\gamma}$ agonist test and ${\alpha}$-glucosidase inhibition assay. Total 16 herb plants had a PPAR-${\gamma}$ agonist activity. Specially, Alisma orientale Juz (108.41%), Ephedra sinica (98.22%), Sasa japonica Makino var. purpurascens Nakai (140.68%), Astragalus membranaceus Bunge (106.79%) and Cnidium officinale Makino (113.00%) showed high PPAR-${\gamma}$ agonist activity rate compared with rosiglitazone's (167.46%). And Cornus officinalis S. et Z. (90.3%), Cinnamomum cassia Blume (89.2%), Psoralea corylifolia L. (89.8%), Paeonia japonica (Makino) Miyabe (92.4%) and Paeonia suffruticosa Andr (93.2%), showed high ${\alpha}$-glucosidase inhibition rates. These results support previous reports of the efficacy of Oriental medicinal plants used for diabetes mellitus.

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References

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