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Safety and Efficacy of Ultrasound-Guided Fiducial Marker Implantation for CyberKnife Radiation Therapy

  • Kim, Jae-Hyun (Department of Radiology, Soonchunhyang University Seoul Hospital) ;
  • Hong, Seong-Sook (Department of Radiology, Soonchunhyang University Seoul Hospital) ;
  • Kim, Jung-Hoon (Department of Radiology, Soonchunhyang University Seoul Hospital) ;
  • Park, Hyun-Jeong (Department of Radiology, Soonchunhyang University Seoul Hospital) ;
  • Chang, Yun-Woo (Department of Radiology, Soonchunhyang University Seoul Hospital) ;
  • Chang, A-Ram (Department of Radiation Oncology, Soonchunhyang University Seoul Hospital) ;
  • Kwon, Seok-Beom (Department of Neurology, Hallym University College of Medicine)
  • 발행 : 2012.06.01

초록

Objective: To evaluate the safety and technical success rate of an ultrasound-guided fiducial marker implantation in preparation for CyberKnife radiation therapy. Materials and Methods: We retrospectively reviewed 270 percutaneous ultrasound-guided fiducial marker implantations in 77 patients, which were performed from June 2008 through March 2011. Of 270 implantations, 104 were implanted in metastatic lymph nodes, 96 were in the liver, 39 were in the pancreas, and 31 were in the prostate. During and after the implantation, major and minor procedure-related complications were documented. We defined technical success as the implantation enabling adequate treatment planning and CT simulation. Results: The major and minor complication rates were 1% and 21%, respectively. One patient who had an implantation in the liver suffered severe abdominal pain, biloma, and pleural effusion, which were considered as major complication. Abdominal pain was the most common complication in 11 patients (14%). Among nine patients who had markers inserted in the prostate, one had transient hematuria for less than 24 hours, and the other experienced transient voiding difficulty. Of the 270 implantations, 261 were successful (97%). The reasons for unsuccessful implantations included migration of fiducial markers (five implantations, 2%) and failure to discriminate the fiducial markers (three implantations, 1%). Among the unsuccessful implantation cases, six patients required additional procedures (8%). Conclusion: The symptomatic complications following ultrasound-guided percutaneous implantation of fiducial markers are relatively low. However, careful consideration of the relatively higher rate of migration and discrimination failure is needed when performing ultrasound-guided percutaneous implantations of fiducial markers.

키워드

참고문헌

  1. Chang SD, Main W, Martin DP, Gibbs IC, Heilbrun MP. An analysis of the accuracy of the CyberKnife: a robotic frameless stereotactic radiosurgical system. Neurosurgery 2003;52:140- 146; discussion 146-147
  2. Sotiropoulou E, Stathochristopoulou I, Stathopoulos K, Verigos K, Salvaras N, Thanos L. CT-guided fiducial placement for cyberknife stereotactic radiosurgery: an initial experience. Cardiovasc Intervent Radiol 2010;33:586-589 https://doi.org/10.1007/s00270-009-9748-7
  3. Kothary N, Heit JJ, Louie JD, Kuo WT, Loo BW Jr, Koong A, et al. Safety and efficacy of percutaneous fiducial marker implantation for image-guided radiation therapy. J Vasc Interv Radiol 2009;20:235-239 https://doi.org/10.1016/j.jvir.2008.09.026
  4. Leskell L. Stereotaxis and Radiosurgery: an operative system. Springfield, IL: Charles C. Thomas, 1971:5-51
  5. Lax I, Blomgren H, Larson D, Näslund I. Extracranial stereotactic radiosurgery of localized targets. J Radiosurg 1998;1:135-148 https://doi.org/10.1023/B:JORA.0000010898.87146.2e
  6. Chang SD, Murphy MI, Martin DP, Hancock SL, Doty JR, Adler JR. Image-guided robotic radiosurgery: clinical and radiographic results with the CyberKnife. Radiosurgery 1999;3:23-3
  7. Shirato H, Harada T, Harabayashi T, Hida K, Endo H, Kitamura K, et al. Feasibility of insertion/implantation of 2.0-mmdiameter gold internal fiducial markers for precise setup and real-time tumor tracking in radiotherapy. Int J Radiat Oncol Biol Phys 2003;56:240-24 https://doi.org/10.1016/S0360-3016(03)00076-2
  8. Adler JR Jr, Murphy MJ, Chang SD, Hancock SL. Image-guided robotic radiosurgery. Neurosurgery 1999;44:1299-1306; discussion 1306-1307
  9. Chang SD, Adler JR. Robotics and radiosurgery--the cyberknife. Stereotact Funct Neurosurg 2001;76:204-208 https://doi.org/10.1159/000066719
  10. Ryu SI, Chang SD, Kim DH, Murphy MJ, Le QT, Martin DP, et al. Image-guided hypo-fractionated stereotactic radiosurgery to spinal lesions. Neurosurgery 2001;49:838-846
  11. Berbeco RI, Nishioka S, Shirato H, Chen GT, Jiang SB. Residual motion of lung tumours in gated radiotherapy with external respiratory surrogates. Phys Med Biol 2005;50:3655-3667 https://doi.org/10.1088/0031-9155/50/16/001
  12. Kothary N, Dieterich S, Louie JD, Chang DT, Hofmann LV, Sze DY. Percutaneous implantation of fiducial markers for imaging-guided radiation therapy. AJR Am J Roentgenol 2009;192:1090-1096 https://doi.org/10.2214/AJR.08.1399
  13. Cardella JF, Bakal CW, Bertino RE, Burke DR, Drooz A, Haskal Z, et al. Quality improvement guidelines for imageguided percutaneous biopsy in adults. J Vasc Interv Radiol 2003;14:S227-S230 https://doi.org/10.1097/01.RVI.0000058325.82956.63

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  1. Evaluation of different fiducial markers for image-guided radiotherapy and particle therapy vol.54, pp.suppl1, 2012, https://doi.org/10.1093/jrr/rrt071
  2. CT-Guided Implantation of Intrahepatic Fiducial Markers for Proton Beam Therapy of Liver Lesions: Assessment of Success Rate and Complications vol.204, pp.2, 2015, https://doi.org/10.2214/ajr.14.12901
  3. Technical advances in endoscopic ultrasound-guided fiducial placement for the treatment of pancreatic cancer vol.3, pp.4, 2012, https://doi.org/10.1055/s-0034-1392274
  4. Transarterial Fiducial Marker Placement for Image-guided Proton Therapy for Malignant Liver Tumors vol.38, pp.5, 2012, https://doi.org/10.1007/s00270-014-1013-z
  5. Körperstereotaxie bei urologischen Tumoren vol.18, pp.12, 2012, https://doi.org/10.1007/s15015-015-1828-8
  6. Clinical study on the influence of motion and other factors on stereotactic radiotherapy in the treatment of adrenal gland tumor vol.9, pp.None, 2012, https://doi.org/10.2147/ott.s107106
  7. Therapeutic usability of two different fiducial gold markers for robotic stereotactic radiosurgery of liver malignancies: A pilot study vol.8, pp.17, 2012, https://doi.org/10.4254/wjh.v8.i17.731
  8. Körperstereotaxie bei urologischen Tumoren vol.20, pp.2, 2012, https://doi.org/10.1007/s00092-016-0908-1
  9. Percutaneous fiducial marker placement prior to stereotactic body radiotherapy for malignant liver tumors: an initial experience vol.57, pp.2, 2012, https://doi.org/10.1093/jrr/rrv099
  10. Biodegradable fiducial markers for X-ray imaging - soft tissue integration and biocompatibility vol.4, pp.34, 2016, https://doi.org/10.1039/c6tb01001f
  11. Robust augmented reality registration method for localization of solid organs’ tumors using CT-derived virtual biomechanical model and fluorescent fiducials vol.31, pp.7, 2017, https://doi.org/10.1007/s00464-016-5297-8
  12. Correlation of liver and pancreas tumor motion with normal anatomical structures determined with deformable image registration vol.3, pp.1, 2017, https://doi.org/10.1088/2057-1976/aa54d0
  13. Efficacy and safety of ultrasound-guided implantation of fiducial markers in the liver for stereotactic body radiation therapy vol.12, pp.6, 2017, https://doi.org/10.1371/journal.pone.0179676
  14. A block matching based approach with multiple simultaneous templates for the real-time 2D ultrasound tracking of liver vessels vol.44, pp.11, 2012, https://doi.org/10.1002/mp.12574
  15. Clinical Implications of a Novel, Iron-containing Fiducial Marker in Radiotherapy for Liver Tumors: An Initial Experience vol.9, pp.12, 2012, https://doi.org/10.7759/cureus.1902
  16. Robotic radiosurgery treatment in liver tumors: Early experience from an Indian center vol.7, pp.3, 2018, https://doi.org/10.4103/sajc.sajc_19_18
  17. A fiducial-less tracking method for radiation therapy of liver tumors by diaphragm disparity analysis part 1: simulation study using machine learning through artificial neural network vol.7, pp.3, 2012, https://doi.org/10.1007/s13566-018-0358-3
  18. Safety and efficacy of fiducial marker implantation for robotic stereotactic body radiation therapy with fiducial tracking vol.14, pp.1, 2019, https://doi.org/10.1186/s13014-019-1373-2
  19. Role of endoscopic ultrasonography guided fiducial marker placement in gastrointestinal cancer vol.36, pp.5, 2012, https://doi.org/10.1097/mog.0000000000000662
  20. Prospective evaluation of fiducial marker placement quality and toxicity in liver CyberKnife stereotactic body radiotherapy vol.38, pp.4, 2012, https://doi.org/10.3857/roj.2020.00472
  21. Percutaneous insertion of hepatic fiducial true-spherical markers for real-time adaptive radiotherapy vol.29, pp.6, 2012, https://doi.org/10.1080/13645706.2019.1663217
  22. EUS-guided placement of fiducial markers for image-guided radiotherapy in gastrointestinal tumors: A critical appraisal vol.10, pp.6, 2012, https://doi.org/10.4103/eus-d-20-00116
  23. Utility of real-time image fusion technology in ultrasonography-guided fiducial marker implantation for stereotactic body radiation therapy for liver tumors vol.62, pp.5, 2012, https://doi.org/10.1177/0284185120934479