DOI QR코드

DOI QR Code

Portal Vein Thrombosis with a Lung Abscess

폐농양과 동반된 간문맥 혈전증 1예

  • Park, Sung-Nam (Department of Internal Medicine, Wallace Memorial Baptist Hospital) ;
  • Yim, Ju-Kyeon (Department of Internal Medicine, Wallace Memorial Baptist Hospital) ;
  • Kim, Yeong-Muk (Department of Internal Medicine, Wallace Memorial Baptist Hospital)
  • 박성남 (왈레스 기념 침례병원 내과) ;
  • 임주견 (왈레스 기념 침례병원 내과) ;
  • 김영묵 (왈레스 기념 침례병원 내과)
  • Published : 2012.01.01

Abstract

Portal vein thrombosis (PVT) is an uncommon cause of presinusoidal hypertension and can result from cirrhosis, malignancy, infection, inflammation, and congenital and acquired thrombophilic states. Infectious and inflammatory causes include pylephlebitis, omphalitis, diverticulitis, pancreatitis, cholecystitis, appendicitis, and inflammatory bowel disease. However, PVT induced by a lung abscess has not been reported. We experienced a 50-year-old male complaining of right upper quadrant pain, fever, and coughing. A lung abscess and PVT were revealed by computed tomography and abdominal Doppler ultrasonography. The PVT resolved, in part, after an 8-day course of antibiotic therapy. We report a case of PVT as a complication of a lung abscess and review the literature.

저자들은 폐농양에 합병된 간문맥 혈전증 환자에서 항응고요법 없이 항생제 치료만으로 폐농양의 호전과 함께 일부용해된 간문맥 혈전증 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

  1. Rajani R, Bjornsson E, Bergquist A, et al. The epidemiology and clinical features of portal vein thrombosis: a multicentre study. Aliment Pharmacol Ther 2010;32:1154-1162. https://doi.org/10.1111/j.1365-2036.2010.04454.x
  2. Parikh S, Shah R, Kapoor P. Portal vein thrombosis. Am J Med 2010;123:111-119. https://doi.org/10.1016/j.amjmed.2009.05.023
  3. Okuda K, Ohnishi K, Kimura K, et al. Incidence of portal vein thrombosis in liver cirrhosis: an angiographic study in 708 patients. Gastroenterology 1985;89:279-286. https://doi.org/10.1016/0016-5085(85)90327-0
  4. Amitrano L, Guardascione MA, Brancaccio V, et al. Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis. J Hepatol 2004;40:736-741. https://doi.org/10.1016/j.jhep.2004.01.001
  5. Onohara T, Takahashi I, Nishizaki T, Wakasugi K, Matsusaka T, Kume K. Superior mesenteric vein thrombosis due to diverticulitis and spontaneous thrombolysis after ilio-cecal resection: a case report. J Cardiovasc Surg (Torino) 2000; 41:307-309.
  6. Wakefield TW, Greenfield LJ, Rolfe MW, et al. Inflammatory and procoagulant mediator interactions in an experimental baboon model of venous thrombosis. Thromb Haemost 1993;69:164-172.
  7. Valla DC, Condat B, Lebrec D. Spectrum of portal vein thrombosis in the West. J Gastroenterol Hepatol 2002;17(Suppl 2): S224-S227. https://doi.org/10.1046/j.1440-1746.17.s3.4.x
  8. Sarin SK, Sollano JD, Chawla YK, et al. Consensus on extra-hepatic portal vein obstruction. Liver Int 2006;26:512-519. https://doi.org/10.1111/j.1478-3231.2006.01269.x
  9. Harris KW, Esmon CT. Protein S is required for bovine platelets to support activated protein C binding and activity. J Biol Chem 1985;260:2007-2010.
  10. Castoldi E, Hackeng TM. Regulation of coagulation by protein S. Curr Opin Hematol 2008;15:529-536. https://doi.org/10.1097/MOH.0b013e328309ec97
  11. Fisher NC, Wilde JT, Roper J, Elias E. Deficiency of natural anticoagulant proteins C, S, and antithrombin in portal vein thrombosis: a secondary phenomenon? Gut 2000;46:534-539. Erratum in: Gut 2000;47:158. https://doi.org/10.1136/gut.46.4.534
  12. Oh YM, Kim JS, Jeong JY, Choi SH, Park SK. Cerebral venous sinus thrombosis associated with protein S deficiency in a child. Clin Pediatr Hematol Oncol 2008;15:127-133.
  13. Ponziani FR, Zocco MA, Campanale C, et al. Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment. World J Gastroenterol 2010;16:143-155. https://doi.org/10.3748/wjg.v16.i2.143
  14. Kang YH, Song MS, Eom TM. A case of portal veinthrombosis caused by protein C and S deficiency associated with cytomegalovirus infection. Inje Med J 2009;30:77-81.
  15. Kim WS, Lee JW, Lee ES, et al. A case of isolated superior mesenteric vein thrombosis in acute pancreatitis. Korean J Gastroenterol 2002;40:68-71.
  16. Park JH, Cho YK, Lee MS, et al. A case report of suprerior mesenteric vein thrombosis associated with diverticulitis. Korean J Med 1999;57:114-117.

Cited by

  1. Portal Vein Thrombosis with Sepsis Caused by Inflammation at Colonic Stent Insertion Site vol.65, pp.5, 2012, https://doi.org/10.4166/kjg.2015.65.5.316