Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
권호 표지
DOI QR코드

DOI QR Code

Acute Coronary Stent Thrombosis in Cancer Patients: A Case Series Report

  • Lee, Joo-Myung (Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital) ;
  • Yoon, Chang-Hwan (Division of Cardiology, Department of Internal Medicine, Seoul National University Bundang Hospital)
  • Published : 2012.07.31
⟨ Previous Next ⟩

Abstract

There have been a growing numbers of patients diagnosed with malignancy and coronary artery disease simultaneously or serially. In the era of percutaneous coronary intervention (PCI), stent thrombosis has been a rare but challenging problem. Recently, we experienced two unique cases of acute stent thrombosis in patients with malignancy. The first case showed acute and subacute stent thrombosis after PCI. The second case revealed simultaneous thromboses in stent and non-treated native coronary artery. We believe that we need rigorous precautions in the treatment of patients with coronary artery disease and malignancy, especially with regards to deciding how and whether to revascularize, as well as which anti-platelet agents to select.

Keywords

References

  1. Iakovou I, Schmidt T, Bonizzoni E, et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA 2005;293:2126-30. https://doi.org/10.1001/jama.293.17.2126
  2. Blich M, Zeidan-Shwiri T, Petcherski S, Osherov A, Hammerman H. Incidence, predictors and outcome of drug-eluting stent thrombosis in real- world practice. J Invasive Cardiol 2010;22:461-4.
  3. Lee AY. Thrombosis in cancer: an update on prevention, treatment, and survival benefits of anticoagulants. Hematology Am Soc Hematol Educ Program 2010;2010:144-9. https://doi.org/10.1182/asheducation-2010.1.144
  4. Khorana AA, Connolly GC. Assessing risk of venous thromboembolism in the patient with cancer. J Clin Oncol 2009;27:4839-47. https://doi.org/10.1200/JCO.2009.22.3271
  5. De Cicco M. The prothrombotic state in cancer: pathogenic mechanisms. Crit Rev Oncol Hematol 2004;50:187-96. https://doi.org/10.1016/j.critrevonc.2003.10.003
  6. Nakagawa T, Yasuno M, Tanahashi H, et al. A case of acute myocardial infarction: intracoronary thrombosis in two major coronary arteries due to hormone therapy. Angiology 1994;45:333-8. https://doi.org/10.1177/000331979404500501
  7. Canale ML, Camerini A, Stroppa S, et al. A case of acute myocardial infarction during 5-fluorouracil infusion. J Cardiovasc Med (Hagerstown) 2006;7:835-7. https://doi.org/10.2459/01.JCM.0000250874.09273.9b
  8. Wijesinghe N, Thompson PI, McAlister H. Acute coronary syndrome induced by capecitabine therapy. Heart Lung Circ 2006;15:337-9. https://doi.org/10.1016/j.hlc.2006.03.010
  9. Kalapura T, Krishnamurthy M, Reddy CV. Acute myocardial infarction following gemcitabine therapy: a case report. Angiology 1999;50:1021-5. https://doi.org/10.1177/000331979905001208
  10. Gemici G, Cinçin A, Degertekin M, Oktay A. Paclitaxel-induced ST-segment elevations. Clin Cardiol 2009;32:E94-6. https://doi.org/10.1002/clc.20291
  11. Lee SP, Suh JW, Park KW, et al. Study design and rationale of 'Influence of Cilostazol-based triple anti-platelet therapy on ischemic complication after drug-eluting stent implantation (CILON-T)' study: a multicenter randomized trial evaluating the efficacy of Cilostazol on ischemic vascular complications after drug-eluting stent implantation for coronary heart disease. Trials 2010;11:87. https://doi.org/10.1186/1745-6215-11-87
  12. Gurbel PA, Bliden KP, Butler K, et al. Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the respond study. Circulation 2010;121:1188-99. https://doi.org/10.1161/CIRCULATIONAHA.109.919456
  13. Montalescot G, Wiviott SD, Braunwald E, et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial. Lancet 2009;373:723-31. https://doi.org/10.1016/S0140-6736(09)60441-4

Cited by

  1. Management of CAD in Patients with Active Cancer: the Interventional Cardiologists’ Perspective vol.19, pp.6, 2012, https://doi.org/10.1007/s11886-017-0862-x
  2. Treatment of coronary artery disease in cancer survivors: an emerging challenge vol.28, pp.1, 2012, https://doi.org/10.1097/mca.0000000000000444
  3. Acute Coronary Syndrome in Cancer Patients vol.18, pp.5, 2012, https://doi.org/10.1007/s40256-018-0286-z
  4. Cancer and Coronary Artery Disease: Common Associations, Diagnosis and Management Challenges vol.20, pp.6, 2012, https://doi.org/10.1007/s11864-019-0644-3