Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas

  • Onur, Mehmet Ruhi (Department of Radiology, University of Firat, Faculty of Medicine, Firat Universitesi Hastanesi Rektorluk Kampusu) ;
  • Yalniz, Mehmet (Department of Gastroenterology, University of Firat, Faculty of Medicine, Firat Universitesi Hastanesi Rektorluk Kampusu) ;
  • Poyraz, Ahmet Kursad (Department of Radiology, University of Firat, Faculty of Medicine, Firat Universitesi Hastanesi Rektorluk Kampusu) ;
  • Ozercan, Ibrahim Hanifi (Department of Pathology, University of Firat, Faculty of Medicine, Firat Universitesi Hastanesi Rektorluk Kampusu) ;
  • Ozkan, Yusuf (Department of Endocrinology, University of Firat, Faculty of Medicine, Firat Universitesi Hastanesi Rektorluk Kampusu)
  • Published : 2012.02.01
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Abstract

A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis.

Keywords

References

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