The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Renal Infarction after NSAID Treatment

비스테로이드 소염제 복용 후 발생한 신경색

  • Yoon, Se-Hee (Department of Internal Medicine, Kyungpook National University School of Medicine) ;
  • Kim, Yong-Lim (Department of Internal Medicine, Kyungpook National University School of Medicine) ;
  • Park, Sun-Hee (Department of Internal Medicine, Kyungpook National University School of Medicine) ;
  • Kim, Chan-Duck (Department of Internal Medicine, Kyungpook National University School of Medicine) ;
  • Choi, Ji-Young (Department of Internal Medicine, Kyungpook National University School of Medicine) ;
  • Yun, Sung-Ro (Department of Internal Medicine, Konyang University College of Medicine)
  • 윤세희 (경북대학교 의학전문대학원 내과학교실) ;
  • 김용림 (경북대학교 의학전문대학원 내과학교실) ;
  • 박선희 (경북대학교 의학전문대학원 내과학교실) ;
  • 김찬덕 (경북대학교 의학전문대학원 내과학교실) ;
  • 최지영 (경북대학교 의학전문대학원 내과학교실) ;
  • 윤성로 (건양대학교 의과대학 내과학교실)
  • Published : 2012.05.01
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Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are popular in general practice. Their adverse renal effects have been well documented. Common NSAID-related renal side effects range from dysfunctional renal hemodynamic responses, nephrotic syndrome, electrolyte disturbances, acute interstitial nephritis, chronic interstitial nephritis with papillary necrosis, and acute flank pain syndrome to acute renal failure. Decreased prostaglandin synthesis can lead to renal ischemia and hemodynamically related acute renal failure. Cases of acute renal failure syndrome accompanied by severe loin pain after anaerobic exercise (ALPE) or binge drinking have previously been reported in individuals taking NSAIDs. However, severe flank pain after high-dose NSAID treatment in the absence of other conditions (exercise or volume contraction) is rare. We report a case of a 51-year-old man who suffered from severe pain in both flanks after NSAID treatment. Computed tomography revealed hypodense lesions in both kidneys.

저자 등은 건장한 성인에서 탈수, 음주, 운동 등 다른 원인 없이 고용량의 비스테로이드 소염진통제로 인한 신허혈과 동반된 신경색 1예를 경험하여 보고하는 바이다.

Keywords

References

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