CELLMED (셀메드)

Cellmed Orthocellular Medicine and Pharmaceutical Association (셀메드 세포교정의약학회)
권호 표지
DOI QR코드

DOI QR Code

Mild stimulation of stomach 36 acupuncture point by organic nanoscale SP6 patch improves cellular physiologic functional status of different organs

  • Nazeran, Homer (Electrical and Computer Engineering, University of Texas at El Paso) ;
  • Blake-Greenberg, Sherry (Health Integration Therapy, Palos Verdes Estates) ;
  • Haltiwanger, Emily (Rehabilitation Sciences Department, College of Health Sciences, University of Texas at El Paso)
  • Received : 2011.07.04
  • Accepted : 2012.02.29
  • Published : 2012.02.29
Download PDF
⟨ Previous Next ⟩

Abstract

Acupuncture works by stimulating peripheral sensory nerves and their endings causing an increase in cutaneous blood flow and microcirculation, as well as release of neurotransmitters, neuropeptides, and hormones. SP6 Patch is a nanoscale nontransdermal device that mildly stimulates Stomach 36 (zusanli) and other acupuncture points. As stimulation of these points has been indicated to have an effect on hypothalamic function, it is of great research interest to investigate the effect of SP6 Patch on the physiology of organs that are affected by hypothalamic regulation. Bioelectrical tissue impedance data indicative of cellular physiologic organ function, using an Electro Interstitial Scan (EIS) system, were acquired from hypothalamus, pancreas, liver, intestines, kidneys, thyroid and adrenal glands in 10 (1 male, 9 females) volunteers while wearing the SP6 Patch daily for 1 week. EIS testing was performed at baseline with no patch, 30 min after wearing the patch, and after wearing the patch 12 h/day for 1 week. Subjects were instructed to keep well hydrated during the study period. All subjects served as their own control. The hypothesis was: The SP6 Patch worn 12 h/day on the Stomach 36 acupuncture point for 1 week, may significantly improve cellular physiologic functional status of different organs measured by EIS. All tested organs achieved significant improvement in their functional physiologic status after wearing the SP6 Pach 12 h/day for 1 week compared to baseline with an overall average statistical power > 89%. Based upon these results the hypothesis was accepted as true.

Keywords

References

  1. Bard AJ, Faulkner LR. Electrochemical Methods: Fundamentals and applications. 2nd ed. (New York: Wiley), 2001.
  2. Budzynski T, Budzynski H, Maret K, Tang, H. Heart Rate Variability Enhancement Through Nanotechnology: A Double Blind Randomized-Control Pilot Study. J Neurother. 2008;12(1):45-55. https://doi.org/10.1080/10874200802219905
  3. Cai W. Acupuncture and the nervous system, Am J Chin Med. 1992;20:331-337. https://doi.org/10.1142/S0192415X92000369
  4. Cotter G, Schachner A, Sasson L, Dekel H, Moshkovitz Y. Impedance cardiography revisited. Physiol Meas. 2006; 27:817-827. https://doi.org/10.1088/0967-3334/27/9/005
  5. Critchley LA. Impedance cardiography: The impact of new technology. Anaesthesia. 1998;53:677-684. https://doi.org/10.1046/j.1365-2044.1998.437-az0550.x
  6. Hsieh J C, Tu C H, Chen FP, Chen MC, Yeh TC, Cheng HC, Wu YT, Liu RS, Ho LT. Activation of the hypothalamus characterizes the acupuncture stimulation at the analgesic point in human: a positron emission tomography study. Neurosci Lett. 2001;307:105-108. https://doi.org/10.1016/S0304-3940(01)01952-8
  7. Komori M, Takada K, Tomizawa Y, Nishiyama K, Kondo I, Kawamata M, Ozaki M. Microcirculation responses to acupuncture stimulation and phototherapy. Anesth Analg. 2009;108(2):635-640. https://doi.org/10.1213/ane.0b013e31819317bc
  8. Lin J H, Su HL, Chang SH, Shien YS, Wu LS. Treatment of iatrogenic Cushing's Syndrome in dogs with electroacupuncture stimulation of Stomach 36. Am J Chin Med. 1991;19:9-15. https://doi.org/10.1142/S0192415X9100003X
  9. Litscher G, Wang L, Schiora D, Rachbauer D, Schwarz G, Schopfer A, Ropele S, Huber E. (Scwarz G, Schopfer A, Ropele S Huber E.) Biological effects of painless laser needle acupuncture. Med Acupunct. 2004;16(1):24-29.
  10. Litscher G, and Wang L. Biomedical engineering meets acupuncture, development of a miniaturized 48-channel skin impedance measurement system for needle and laser acupuncture. Biomed Eng Online. 2010;9:78. https://doi.org/10.1186/1475-925X-9-78
  11. Litscher G. Bioengineering assessment of acupuncture. Part 1: thermography. Crit Rev Biomed Eng. 2006a;34(1):1-22. https://doi.org/10.1615/CritRevBiomedEng.v34.i1.10
  12. Litscher G. Bioengineering assessment of acupuncture. Part 2: monitoring of microcirculation. Crit Rev Biomed Eng. 2006b;34(4):273-294. https://doi.org/10.1615/CritRevBiomedEng.v34.i4.10
  13. Litscher G. Bioengineering assessment of acupuncture. Part 3: ultrasound. Crit Rev Biomed Eng. 2006c;34(4):295-326. https://doi.org/10.1615/CritRevBiomedEng.v34.i4.20
  14. Litscher G. Bioengineering assessment of acupuncture. Part 4: functional magnetic resonance imaging. Crit Rev Biomed Eng. 2006d;34(4):327-345. https://doi.org/10.1615/CritRevBiomedEng.v34.i4.30
  15. Litscher G. Bioengineering assessment of acupuncture. Part 5: cerebral near-infrared spectroscopy. Crit Rev Biomed Eng. 2006e;34(6):439-457. https://doi.org/10.1615/CritRevBiomedEng.v34.i6.10
  16. Litscher G. Bioengineering assessment of acupuncture. Part 6: monitoring—neurophysiology. Crit Rev Biomed Eng. 2007a; 35(1):1-38. https://doi.org/10.1615/CritRevBiomedEng.v35.i1-2.10
  17. Litscher G. Bioengineering assessment of acupuncture. Part 7: heart rate variability. Crit Rev Biomed Eng. 2007b;35(3-4):183-195. https://doi.org/10.1615/CritRevBiomedEng.v35.i3-4.10
  18. Lu AP, Jia HW, Xiao C, Lu QP. Theory of traditional Chinese medicine and therapeutic method of diseases. World J Gastroentrol. 2004;10(13):1854-1856. https://doi.org/10.3748/wjg.v10.i13.1854
  19. Morimoto T, Kinouchi Y, Iritani T, Kimura S, Konishi Y, Mitsuyama N, Komaki K, Monden Y. Measurement of the electrical bio-impedance of breast tumors. Eur Surg Res. 1990;22:86-92. https://doi.org/10.1159/000129087
  20. Nazeran H. Heart rate variability signal parameters quantify skin cooling effect of energy patches during rest and exercise in young healthy individuals. Biomedical Engineering Recent Developments. Wilson, Tran, Vossoughi, Editors. 2007;13-19.
  21. Nazeran H, Greenberg S. Nanoscale carnosine patches improve organ function. SBEC 2010. International Federation of Medical and Biological Engineering Proceedings 32. 2010a; pp 138-141.
  22. Nazeran H, Greenberg S. Nanoscale glutathione patches improve organ function. SBEC 2010. International Federation of Medical and Biological Engineering Proceedings 32. 2010b; 134-137.
  23. NCCAM (National Center for Complementary and Alternative Medicine) 1, Assessed February 2012. http://nccam.nih.gov/health/whatiscam/chinesemed.htm
  24. NCCAM (National Center for Complementary and Alternative Medicine) 2, Assessed February 2012 http://nccam.nih.gov/health/acupuncture/introduction.htm.
  25. Shen X, Ding G, Wei J, Zhao L, Zhoua Y, Denga H, Laoc L. An infrared radiation study of the biophysical characteristics of traditional moxibustion. Comp Therap Med. 2006;14:213-219. https://doi.org/10.1016/j.ctim.2005.09.003
  26. Sherwood L. Fundamentals of physiology: a human perspective, 2nd ed. (St. Paul: West Publishing), pp. 98-99, 1995.
  27. U.S. Department of Health and Human Services: Food and Drug Administration: FDA's Role. 2009.
  28. Van De Water JM, Miller TW, Vogel RL, Mount BE, Dalton ML. Impedance cardiography: the next vital sign technology? Chest. 2003;123:2028-2033. https://doi.org/10.1378/chest.123.6.2028

Cited by

  1. A double-blind placebo-controlled heart rate variability investigation to evaluate the quantitative effects of the organic nanoscale aeon patch on the autonomic nervous system vol.5, pp.1, 2012, https://doi.org/10.5667/tang.2014.0024