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고혈압노인과 정상혈압노인 및 청년의 식후혈압 변화 비교

Postprandial Blood Pressure in Hypertensive and Normotensive Elderly and Young Adult Subjects

  • 손정태 (대구가톨릭대학교 간호대학 간호과학연구소)
  • Son, Jung Tae (Research Institute of Nursing Science, College of Nursing, Catholic University of Daegu)
  • 투고 : 2012.10.26
  • 심사 : 2012.12.06
  • 발행 : 2012.12.31

초록

본 연구는 고혈압노인과 정상혈압노인 그리고 청년 간의 식후혈압 변화 양상의 차이를 파악하기 위하여 참여자들의 서면동의를 받아 조사하였다. 휴대용 혈압모니터(ABPM)를 사용하여 식전 30분부터 식후 90분까지 15분 간격으로 혈압을 측정하였다. 고혈압노인군(26명)은 수축기혈압이 식후 30분부터 식후 90분까지 지속적으로 하강하였고, 최대 $19.3{\pm}19.4mmHg$ 하강하여, 정상혈압노인군(25명: $-7.7{\pm}9.4mmHg$) 및 청년군(26명: $-1.3{\pm}4.1mmHg$)과 차이가 있었다. 고혈압노인군의 식후 이완기혈압은 최대 $25.0{\pm}15.1mmHg$ 하강하였고 정상혈압노인군($-6.1{\pm}6.0mmHg$)과 청년군($-5.7{\pm}5.0mmHg$) 과 차이가 있었다. 고혈압노인군과 정상혈압노인군에서는 맥박수의 변화가 없었고, 청년군에서는 식후 30분에 일시적으로 맥박수가 상승하였다(p=.014). PPH 발생률은 고혈압노인군 73.1%, 정상혈압노인 24% 이었고, 청년군은 PPH 발생자가 없었다(p=.001). 따라서 간호사는 고혈압노인의 식후저혈압을 확인하기 위한 식후혈압 측정을 실시해야 한다. 또한 식후 90분까지는 갑작스런 혈압하강과 관련된 합병증의 발생을 주의관찰하고 관리하도록 하여야 한다.

The aim of this study was to find out the impact of age and hypertensive status on postprandial hypotension(PPH). Twenty-six hypertensive elderly ($77.7{\pm}7.2$ years old), twenty-five normotensive elderly ($80.2{\pm}6.8$ years old) and twenty-six young adults ($20.0{\pm}1.5$ years old) took part in the study. The blood pressure (BP) and heart rates (HR) were measured every 15 minutes, from 30 minutes before a meal to 90 minute after a meal in sitting position, using an ambulatory blood pressure monitor. In the hypertensive group, postprandial reduction in systolic BP continued from 30minutes to 90minutes. The reductuion rate of systolic BP of hypertensive elderly group was significantly greater than other groups (p<.05). However, there were no significant differences in trend of HR change between the groups (p=.082). The incidence of PPH was significantly higher in the hypertensives than other groups (73.1% vs 24% vs 0%, respectively, p=.001). In conclusion, age and hypertensive status had a significant impact on PPH. Elderly persons require more intensive BP monitoring and nursing intervention.

키워드

참고문헌

  1. R. W. Jansen, & L. A. Lipsitz (1995). Postprandial Hypotension: Epidemiology, Pathophysiology, and Clinical Management. Annals of Internal Medicine, 122(4), 286-295. https://doi.org/10.7326/0003-4819-122-4-199502150-00009
  2. K. Kohara, Y. Jiang, M. Igase, Y. Takata, T. Fukuoka, T. Okira, T. Kitami, & K. Hiwada (1999). Postprandial Hypotension is Associated with Asymptomatic Cerebrovascular Damage in Essential Hypertensive Patients. Hypertension, 33(1 Pt 2), 565-568, Article(CrossRefLink) https://doi.org/10.1161/01.HYP.33.1.565
  3. D. G. L. Le Couteur, A. A. Fisher, M. W. Davis, & A. J. McLean (2003). Postprandial Systolic Blood Pressure Responses Older People in Residential Care: Association with Risk of Falling. Gerontology, 49(4), 260-264, Article(CrossRefLink) https://doi.org/10.1159/000070408
  4. A. A. Fisher, M. W. Davis, W. Srikusalanukul, & M. M Budge (2005). Postprandial Hypotension Predicts All-Cause Mortality in Older, Low-level Care Residents. American Geriatrics Society, 53(8), 1313-1320, Article(CrossRefLink) https://doi.org/10.1111/j.1532-5415.2005.53415.x
  5. S. K. Kim, & K. N. Noh (2008). A Case of postprandial Hypotension Presenting with Postprandial Dizziness. Korean Journal of Medicine, 75(3), 358-361.
  6. L. C. Vloet, R. Smits, & R. W. Jansen (2003). The Effect of Meals at Different Mealtimes on Blood Pressure and Symptoms in Geriatric Patients with Postprandial Hypotension. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 58(11), 1031-1035, Article(CrossRefLink) https://doi.org/10.1093/gerona/58.11.M1031
  7. G. L. Luciano, M. J. Brennan, & M. B. Rothberg, (2010). Postprandial Hypotension. The American Journal of Medicine, 123(3), 281.e1-281.e6. https://doi.org/10.1016/j.amjmed.2009.06.026
  8. K. L. Jones, D. O'Donovan, A. Russo, J. H. Meyer, J. E. Stevens, Y. Lei, J. Keogh, A. Tonkin, & M. Horowitz (2005). Effects of Drink Volume and Glucose Load on Gastric Emptying and Postprandial Blood Pressure in Healthy Older Subjects. American Journal of Physiology-Gastrointestinal and Liver Physiology, 289(2), G240-G248, Article(CrossRefLink) https://doi.org/10.1152/ajpgi.00030.2005
  9. L. A. Lipsitz, S. M. Ryan, J. A. Parker, R. Freeman, J. Y. Wei, & A. L. Goldberger (1993). Hemodynamic and Autonomic Nervous System Responses to Mixed Meal Ingestion in Healthy Young and Old Subjects and Dysautonomic Patients with Postprandial Hypotension. Ciculation, 87(2), 391-400, Article(CrossRefLink) https://doi.org/10.1161/01.CIR.87.2.391
  10. J. T. Son, & E. Lee (2009). Prevalence and Risk Factors of Postprandial Hypotension in Korean Elderly. Journal of Korean Academy of Nursing, 39(2), 198-206, Article(CrossRefLink) https://doi.org/10.4040/jkan.2009.39.2.198
  11. S. J. Yu, M. S. Song, & H. S. Kim (2002). A Study on the Prevalence and Risk Factors of Postprandial Hypotension among the Community- Dwelling Aged. Journal of Korean Academy of Fundamental Nursing, 9(3), 434-444.
  12. National Hypertension Center (2009). Incidence of Hypertension. Retrived Feb 4, 2009. http://www. hypertension.or.kr/introduce/info07_3.html.
  13. R. W. Jansen, M. M. Kelly-Gagnon, & L. A. Lipsitz (1996). Intraindividual Reproducibility of Postprandial and Orthostatic Blood Pressure Changes in Older Nursing-Home Patients: Relationship with Chronic Use of Cardiovascular Medications. Journal of the American Geriatrics Society, 44(4), 383-389. https://doi.org/10.1111/j.1532-5415.1996.tb06406.x
  14. F. Puisieux, H. Bulckaen, A. L. Fauchais, S. Drumez, F. Salomez-Granier, & P. Dewailly (2000). Ambulatory Blood Pressure Monitoring and Postprandial Hypotension in Elderly Persons with Falls or Syncopes. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 55(9), M535-M540, Article (CrossRefLink) https://doi.org/10.1093/gerona/55.9.M535
  15. A. A. Fisher, M. W. Davis, D. G. L Le Couteur, L. Vloet, & R. W. Jansen (2005). The Effect of Meals at Different Mealtimes on Blood Pressure and Symptoms in Geriatric Patients with Postprandial Hypotension. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 60(2), 184-186, Article(CrossRefLink) https://doi.org/10.1093/gerona/60.2.184
  16. R. Kawaguchi, M. Nomura, H. Miyajima, Y. Nakaya, S Mouri, & S. Ito (2002). Postprandial Hypotension in Elderly Subjects: Spectral Analysis of Heart Rate Variability and Electrogastrograms. Journal of Gastroenterology, 37(2), 87-93, Article(CrossRefLink) https://doi.org/10.1007/s005350200001
  17. N. L Smith, M. B. Pasty, G. H. Rutan, T. Lumley, D. Yanez, P. H. M. Chaves, & R. A. Kronmal (2003). The Association between Time since Last Meal and Blood Pressure in Older Adults: The Cardiovascular Health Study. Journal of the American Geriatrics Society, 51(6), 824-828, Article(CrossRefLink)
  18. T. Grodzicki, M. Rajzer, R. Fagard, E. T. O'Brien, L.Thijs, D. Clement, C. Davidson, P. Palatini, G. Parati, J. Kocemba, & J. A. Staessen (1998). Ambulatory Blood Pressure Monitoring and Postprandial Hypotension in Elderly Patients with Isolated Systolic Hypertension. in Europe (SYST-EUR) Trial Investigators. Journal of Human Hypertension, 12(3), 161-165, Article (CrossRefLink) https://doi.org/10.1038/sj.jhh.1000573
  19. R. W. Jansen, C. M. Connelly, M. M. Kelley-Gagnon, A. Parker, & L. A. Lipsitz (1995). Postprandial Hypotension in Elderly Patients with Unexplained Syncope. Archives of Internal Medicine, 155(9), 945-952, Article (CrossRefLink) https://doi.org/10.1001/archinte.1995.00430090087010
  20. M. D. Lilley (1997). Postprandial Blood Pressure Changes in the Elderly. Journal of Gerontological Nursing, 23(12), 17-25.
  21. C. Imai, H. Muratani, Y. Kimura, N. Kanzatom, S. Takishita, & K. Fukiyama (1998). Effects of Meal Ingestion and Active Standing on Blood Pressure in Patients ${\geq}$60 Years of Age. American Journal of Cardiology, 81, 1310-1314, Article(CrossRefLink) https://doi.org/10.1016/S0002-9149(98)00163-5
  22. N. P. Van Orshoven, P. A. Jansen, I. Oudejans, Y. Schoon, & P. L. Oey (2010). Postprandial Hypotension in Clinical Geriatric Patients and Healthy Elderly: Prevalence Related to Patient Selection and Diagnostic Criteria. Journal of Aging Research, 2010 Sep 30, 243-752.
  23. D. Gentilcore, K. L. Jones, D. G. O'Donovan, M. Okira, T. Kitami, & K. Hiwada (1999). Postprandial Hypotension is Associated with Asymptomatic Cerebrovascular Damage in Essential Hypertensive Patients. Hypertension, 33(1 Pt 2), 565-568. https://doi.org/10.1161/01.HYP.33.1.565
  24. L. C. M. Vloet, R. E. Pel-Little, P. A. F. Jansen, & R. W. Jansen (2005). High Prevalence of Postprandial and Orthostatic Hypotension among Geriatric Patients Admitted to Dutch Hospitals. Journal of Gerontology: Medical Sciences, 60A(10), 1271-1277, Article (CrossRefLink)
  25. E. Lubart, R. Segal, Y. Baumoehl, K. Matron, & A. Leibovitz (2006). Postprandial Hypotension in Long-Term Care Elderly Patients on Enteral Feeding. Journal of American Geriatric Society, 54(9), 1377-1381, Article(CrossRefLink) https://doi.org/10.1111/j.1532-5415.2006.00839.x
  26. C. Villavicencio-Chavez, R. Miralles Basseda, P. Gonzalez Marin, & A. M. Cervera (2009). Orthostatic and Postprandial Hypotension in Elderly Patients with Chronic Disease and Disability: Prevalence and Related Factors. Revista Espanola de Gerontología y Geriatria, 44(1), 12-18. https://doi.org/10.1016/j.regg.2008.07.003
  27. W. S. Aronow, & C. Ahn (1997). Association of postprandial hypotension with incidence of falls, syncope, coronary events, stroke, and total mortality at 29-month follow-up in 499 older nursing home residents. Journal of the American Geriatrics Society, 45(9), 1051-1053. https://doi.org/10.1111/j.1532-5415.1997.tb05965.x
  28. L. C. Vloet, D. J. Mehagnoul-Schipper, W. H. Hoefnagels, & R. W. Jansen (2001). The Influence of Low-, Normal-, and High-Carbohydrate Meals on Blood Pressure in Elderly Patients with Postprandial Hypotension. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 55(9), M535-M540.
  29. R. Visvanathan, R. Chen, M. Garcia, M. Horowitz, & I. Chapman (2005). The Effect of Drinks Made from Simple Sugars on Blood Pressure in Healthy Older People. British Journal of Nutrition, 93(5), 575-579, Article(CrossRefLink) https://doi.org/10.1079/BJN20051401
  30. K. L. Jones, D. O'Donovan, A. Russo, J. H. Meyer, J. E. Stevens, Y. Lei, J. Keogh, A. Tonkin, & M. Horowitz (2005). Effects of Drink Volume and Glucose Load on Gastric Emptying and Postprandial Blood Pressure in Healthy Older Subjects. American Journal of Physiology-Gastrointestinal and Liver Physiology, 289(2), G240-G248, Article(CrossRefLink) https://doi.org/10.1152/ajpgi.00030.2005
  31. J. T. Son & E. Lee (2010). Effect of Water Drinking on the Postprandial Fall of Blood Pressure in the Elderly. Korean Academy of Fundamental Nursing, 17(3), 304-313
  32. H. M. Kuipers, R. W. Jansen, T. L. Peeters, & W. H. Hoefnalgels (1991). The Influence of Food Temperature on Postprandial Blood Pressure Reduction. and its Relation to Substance-p in Healthy Elderly Subjects. Journal of American Geriatrics Society, 39(2), 181-184. https://doi.org/10.1111/j.1532-5415.1991.tb01623.x