Journal of the Korea Academia-Industrial cooperation Society (한국산학기술학회논문지)

The Korea Academia-Industrial cooperation Society (한국산학기술학회)
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The usability of the MR Breast perfusion image and Time-Signal Intensity curve in Breast cancer patients

유방암 환자에서 MR Breast perfusion 영상과 시간-신호강도 곡선의 유용성

  • Cho, Jae-Hwan (Department of Radiological Science, Gyeongsan University College) ;
  • Lee, Hae-Kag (Department of Computer Engineering and Soonchunhyang University)
  • 조재환 (경산1대학 방사선과) ;
  • 이해각 (순천향대학교 컴퓨터공학과)
  • Received : 2011.06.27
  • Accepted : 2011.09.08
  • Published : 2011.09.30
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Abstract

The purpose of this study was to examine the usefulness of MR Breast perfusion image and time-signal intensity curve in patients diagnosed with breast cancer. We selected on 20 patients who were histologically diagnosed to have invasive ductal carcinoma (IDC) from March 2009 to December 2010. First, the Breast perfusion mapping image was reconstructed after obtaining the dynamic contrast enhancement image. The reconstructed image measured the slope, maximal relative enhancement, and time to peak on the detail including the lesion region, normal region, back ground region after obtaining the time-signal intensity curve. The lesion region and normal and slope of the back ground part were measured with the quantitive analytical method about the research and the average was compared and was analyze. In the qualitative analysis, the signal strength of each pixel was analyze with the macroscopic and being high it was low, the medium (2) performed the division of (a) by the three-point standard and the average was measured. The findings from the quantitative image analysis are the following: In the lesion region, the slope and maximal relative enhancement were the highestest among and the time to peak was the highestest in the back ground region. In the qualitative analysis, the breast perfusion image showed a diagnostic efficiency.

본 연구는 유방암 환자를 대상으로 MR Breast perfusion 영상과 시간-신호강도 곡선의 진단적 유용성을 평가하고자 하였다. 2009년 3월부터 2010년 12월까지 조직학적으로 관상피 내암으로 진단 받은 환자 20명을 대상으로 하였다. 우선 역동적 조영 증강 영상을 획득한 후 Breast perfusion 영상을 재구성 하였다. 재구성 된 영상은 시간 강도 그래프를 획득 한 후 병변 부위, 정상 부위, 백그라운드 부위 등 세부위에서 기울기, 최대 상대 조영증강, 최대 조영 증강 시간을 측정 하였다. 실험에 대한 정량적 분석방법으로 병변 부위와 정상 부위, 백그라운드 부위의 기울기를 측정하여 평균값을 비교 분석 하였다. 정성적 분석에서는 육안적으로 각 픽셀의 신호 강도를 분석 하였고 높음(3점), 중간(2점), 낮음(1점)의 구분을 3점 척도로 실시하여 평균값을 측정하였다. 정량적 분석 결과 기울기와 최대 상대 조영증강은 병변 부위에서 가장 높았으며 최대 조영 증강 시간은 백그라운드 부위에서 가장 높았다. 정성적 분석에서는 Breast perfusion 영상은 진단적 가치가 높았다.

Keywords

References

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