한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제28권4호
  • /
  • Pages.352-356
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  • 2011
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

개 파보바이러스성 장염에서 산-염기 장애의 진단

Diagnosis of Acid-Base Disorders in Canine Parvoviral Enteritis

  • 정석영 (강남종합동물병원) ;
  • 김요한 (강원대학교 수의과대학 및 동물의학종합연구소) ;
  • 김두 (강원대학교 수의과대학 및 동물의학종합연구소)
  • Jeoung, Seok-Young (Gangnam Animal Clinic) ;
  • Kim, Yo-Han (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University) ;
  • Kim, Doo (College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University)
  • 심사 : 2011.05.25
  • 발행 : 2011.08.30
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초록

Abstract: This study was aimed to diagnose acid-base disorders of dogs with canine parvoviral enteritis (CPE) and data to establish a rational fluid therapy regimen for patients with CPE. A total of 43 dogs which had clinical signs of CPE and had detected canine parvovirus by polymerase chain reaction, were bled anaerobically from jugular vein at the time of admission. Blood chemical test, determination of electrolytes and blood gas analysis were conducted, and calculated values were obtained from each measured items. The values of blood chemical and electrolytes of dogs with CPE were various depending on the degree of clinical signs, and these tests were not specific to diagnose for CPE. Hypochloremia (20.9%), hyperchloremia (11.6%), hypokalemia (7.0%), hyperkalemia (11.6%), hyponatremia (9.3%) and hypernatremia (18.6%) were diagnosed as abnormalities of electrolytes from 43 dogs with CPE. The 29 out of 43 dogs (67.4%) were metabolic acidosis and 3 dogs (7.0%) were metabolic alkalosis. The acid-base status of 11 dogs out of 43 dogs (25.6%) was normal.

키워드

참고문헌

  1. 김두, 장욱. Polymerase chain reaction을 이용한 canine parvovirus성 장염의 진 단과 역학조사. 한국임상수의학회지 1997; 14: 177-184.
  2. 박종현, 송재영, 이중복, 현방훈, 안수환, 전무형. 국내에서 분리된 Canine Parvovirus의 구조유전자 Cloning과 염기서열 분석. 대한수의학회지 1992; 32: 555-567.
  3. 한홍율, 박희명, 이진희, 오태호, 정순욱, 윤신근, 박철만. 서울지역에서 문제되고 있는 강아지의 급성설사증에 관한 병리학적 연구. 한국임상수의학회지 1993; 10: 171-184.
  4. 한홍율, 황의경, 유규연, 이영옥. 개의 바이러스성 장염의 국내발생보고. 대한수의사회지 1982; 22: 167-170.
  5. Adams LG, Polzin DJ. Mixed acid-base disorders. Vet Clin North Am Small Anim Pract 1989; 19: 307-326.
  6. Adrogue HJ, Madias NE. Changes in plasma potassium concentration during acute acid-base disturbances. Am J Med 1981; 71: 456-467. https://doi.org/10.1016/0002-9343(81)90182-0
  7. Appel MJG, Scott FW, Carmichael LE. Isolation and immunization studies of a canine parvo-like virus from dogs with haemorrhagic enteritis. Vet Rec 1979; 105: 156-159 https://doi.org/10.1136/vr.105.8.156
  8. Brobst D. Pathophyiologic and adaptive changes in acid-base disorders. J Am Vet Med Assoc 1983; 183: 773-780.
  9. Buonavogilia C, Martella V, Pratelli A, Tempesta M, Cavalli A, Buonavoglia D, Bozzo G, Elia G, Decaro N, Carmichael L. Evidence for evolution of canine parvovirus type 2 in Italy. J Gen Virol 2001; 82: 3021-3025.
  10. Carman PS, Povey RC. Pathogenesis of canine parvovirus-2 in dogs: Hematology, serology and virus recovery. Res Vet Sci 1985; 38: 134-140.
  11. DeMorais HSA, DiBartola SP. Mixed acid-base disorders. part I. Clinical approach. Compend Contin Educ Pract Vet 1993; 15: 1619-1626.
  12. DeMorais HSA, DiBartola SP. Mixed acid-base disorders. part II. Clinical disturbances. Compend Contin Educ Pract Vet 1994; 16: 477-488.
  13. DuBose TD. Clinical approach to patients with acid-base disorders. Med Clin North Am 1983; 67: 799-813.
  14. Greenwood NM, Chalmers WSK, Baxendale W, Thompson H. Comparison of isolates of canine parvovirus by restriction enzyme analysis, and vaccine efficacy against field strains. Vet Rec 1995; 136: 63-67. https://doi.org/10.1136/vr.136.3.63
  15. Haskins SC. An overview of acid-base physiology. J Am Vet Med Assoc 1977; 170: 423-428.
  16. Heald RD, Jones BD, Schmidt DA. Blood gas electrolyte concentrations in canine parvoviral enteritis. J Am Anim Hosp Assoc 1986; 22: 745-748.
  17. Ilkiw JE, Rose RJ, Martin ICA. A comparison of simultaneously collected arterial, mixed venous, jugular venous and cephalic venous blood sample in the assessment of blood-gas and acidbase status in the dog. J Vet Int Med 1991; 5: 294-298. https://doi.org/10.1111/j.1939-1676.1991.tb03136.x
  18. Jacobs RM, Weiser MG, Kowalski JJ. Clinicopathologic features of canine parvovirus enteritis. J Am Anim Hosp Assoc 1980; 16: 809-814.
  19. Jeoung SY, Ahn SJ, Kim D. Genetic analysis of VP2 gene of canine parvovirus isolates in Korea. J Vet Med Sci 2008; 70: 719-722. https://doi.org/10.1292/jvms.70.719
  20. Macartney L, MaCandlish IAP, Thomson H, Cornwell HJC. Canine parvovirus enteritis 1: clinical hematopathological and pathological features of experimental infection. Vet Rec 1984; 115: 201-210. https://doi.org/10.1136/vr.115.9.201
  21. Meunier PC, Glickman LT, Appel MJG, Shin SJ. Canine parvovirus in a commercial kennel: epidemiologic and pathologic findings. Cornell Vet 1981; 71: 96-110.
  22. Mochizuki M, San Gabriel MC, Nakatani H, Yoshida M. Comparsion of polymerase chain reaction with virus isolation and haemagglutination assays for the detection of canine parvovirus in faecal specimens. Res Vet Sci 1993; 55: 60-63. https://doi.org/10.1016/0034-5288(93)90035-E
  23. Nakamura M, Tohya Y, Miyazawa T, Mochizuki M, Phung HT, Nguyen NH, Huynh LM, Nguyen LT, Nguyen PN, Nguyen PV, Nguyen NP, Akashi H. A novel antigenic variant of canine parvovirus from a Vietnamese dog. Arch Virol 2004; 149: 2261-2269. https://doi.org/10.1007/s00705-004-0367-y
  24. Parrish CR, Aquadro CF, Lisa Atrassheim M, Evermann JF, Sgro JY, Mohammed HO. Rapid antigenic-type replacement and DNA sequence evolution of canine parvovirus. J Virology 1991; 65: 6544-6552.
  25. Robertson SA. Simple acid-base disorders. Vet Clin North Am Small Anim Pract 1989; 19: 289-306.
  26. Robinson WF, Hardy RM. Clinical signs, diagnosis, and treatment of alkalemia in dogs: 20 cases (1982-1984). J Am Vet Med Assoc 1988; 62: 266-276.
  27. Smith-Carr S, Macintire DK. Canine parvovirus. part II. clinical signs, diagnosis, and treatment. Compend Contin Educ Pract Vet 1997; 19: 291-300.
  28. Truyen U, Steinel A, Bruckner L, Lutz H, Mostl K. Distribution of antigenic types of canine parvovirus in Switzerland, Austria and Germany. Schweiz Arch Tierheilkd 2000; 142: 115-119.
  29. Woods CB, Pollock RVH, Carmichael LE. Canine parvovirus enteritis. J Am Anim Hosp Assoc 1980; 16: 171-179.