Journal of Society of Preventive Korean Medicine (대한예방한의학회지)

Society of Preventive Korean Medicine (대한예방한의학회)
권호 표지

Review of Pharmacological Effects of Scutellaria Baicalensis and Its Bioactive Compounds

황금(黃芩)과 구성 화합물의 약리작용에 대한 고찰

  • Lee, Keon-Suk (Division of Internal Medicine(Stroke Center), School of Korean Medicine, Pusan National University) ;
  • Park, Min-Hee (Division of Internal Medicine(Stroke Center), School of Korean Medicine, Pusan National University) ;
  • Cheon, Mog-Eun (Division of Internal Medicine(Stroke Center), School of Korean Medicine, Pusan National University) ;
  • Hong, Jin-Woo (Division of Internal Medicine(Stroke Center), School of Korean Medicine, Pusan National University) ;
  • Cho, Su-In (Division of Pharmacology, School of Korean Medicine, Pusan National University)
  • 이건석 (부산대학교 한의학전문대학원 임상의학부) ;
  • 박민희 (부산대학교 한의학전문대학원 임상의학부) ;
  • 천목은 (부산대학교 한의학전문대학원 임상의학부) ;
  • 홍진우 (부산대학교 한의학전문대학원 임상의학부) ;
  • 조수인 (부산대학교 한의학전문대학원 약물의학부)
  • Received : 2011.05.04
  • Accepted : 2011.07.25
  • Published : 2011.08.31
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Abstract

Objective : Scutellaria baicalensis is one of the most popular and multi-purpose herb in traditional medicine. It is also useful for its practicability to cultivate in Korea. The purpose of this study is to contribute to researches and applications of scutellaria baicalensis by analyzing and reviewing international researches on the compositions and the effects of scutellaria baicalensis. Methods : This study analyzed 146 articles from PubMed by searching with the keyword "Scutellaria baicalensis", "Huang quin", "Baical Skullcap", "Huang qin", "baical skullcap root", "ogon", "Hwanggeum" and "Hwangkeum", published within the last 10 years(from 2000 to 2009). We reviewed the 146 articles on Scutellaria baicalensis and its active constituents in terms of 'Active constituents', 'Experimental studies', 'Clinical studies', 'Drug interaction', 'Side Effects/Toxicity' and 'Pharmacokinetics'. Results : The active constituents of Scutellaria baicalensis are flavonoids such as baicalein, baicalin, wogonin and oroxylin-A. It is reported that scutellaria baicalensis and its active compounds have antiinflammatory activity, antitumor activity, antioxidant activity, antiviral and antibiotic activity, neuroprotective effects, hepatoprotective effects and cardiovascular effect. Conclusions : This study is aimed to summarize the results obtained within the last 10 years and to contribute to following researches and applications of Scutellaria baicalensis.

Keywords

References

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