Soft Tissue Response of Rabbit Larynx to Implanted Foley Catheter for Short Duration

토끼 후두내 삽입한 풍선도관에 대한 단기 조직 반응

  • Yoo, Young-Sam (Department of Otolaryngology Head and Neck Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Choi, Chan (Department of Otolaryngology Head and Neck Surgery, Sanggye Paik Hospital, College of Medicine, Inje University) ;
  • Kim, Dong-Won (Department of Thoracic and Cardiovascular Surgery, Sanggye Paik Hospital, College of Medicine, Inje University)
  • 유영삼 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 최찬 (인제대학교 의과대학 상계백병원 이비인후과학교실) ;
  • 김동원 (인제대학교 의과대학 상계백병원 흉부외과학교실)
  • Received : 2010.10.27
  • Accepted : 2011.03.15
  • Published : 2011.06.25

Abstract

Objectives : This study was aimed to investigate soft tissue reaction such as inflammation, immune reaction of rabbit larynx to implanted foley catheter. Methods : After 8 rabbits were anesthetized, their thyroid cartilage and trachea were exposed through a skin incision and a 6 French foley catheter was inserted into the thyroid cartilage via cricothyroid membrane and ballooned with normal saline (0.1 mL). The other end of catheters were ligated and cut. The wound was closed keeping catheter under the skin. Two rabbits were used as normal control Larynges were removed for pathologic examination at 4weeks and 8 weeks of the study respectively, Results : Ten rabbits were euthanized for gross and pathologic examination (5 rabbits after 4 weeks and 5 rabbits after 8 weeks). All rabbits survived the study periods and inflammations or foreign body reactions were minimally found on pathologic examinations. Conclusions : Foley catheter could be useful and safe material for vocal fold medialization in rabbit models.

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