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Improvements Caused by Chitosan, Sericin and Collagen Peptide Extract Complexes on Lipid Metabolism in Dyslipidemia

키토산과 세리신 및 콜라겐 펩타이드 추출 혼합물이 이상지질혈증의 지질대사 개선에 미치는 영향

  • Kim, Han-Soo (Department of Food Science & Technology, Pusan National University) ;
  • Jang, Seong-Ho (Department of Bioenvironmental Energy, Pusan National University) ;
  • Yoon, Myung-Joo (Department of Bioenvironmental Energy, Pusan National University) ;
  • Kang, Jin-Soon (School of Food Science, International University of Korea) ;
  • Choi, Woo-Seok (Department of Food Science & Technology, Pusan National University)
  • 김한수 (부산대학교 식품공학과) ;
  • 장성호 (부산대학교 바이오환경에너지학과) ;
  • 윤명주 (부산대학교 바이오환경에너지학과) ;
  • 강진순 (한국국제대학교 식품과학부) ;
  • 최우석 (부산대학교 식품공학과)
  • Received : 2011.05.16
  • Accepted : 2011.07.20
  • Published : 2011.08.31

Abstract

The objective of this study was to assess improvements caused by chitosan, sericin and collagen peptide extract complexes (1:1:1, w/w/w, CSC-F-005) in lipid concentrations in the sera of dyslipidemic rats (SD strain) fed on experimental diets for 5 weeks. Serum concentrations of total cholesterol, HDL-cholesterol, ratio of HDL-cholesterol concentration to total cholesterol, atherosclerotic index, LDL-cholesterol, free cholesterol, cholesteryl ester, triglyceride, phospholipid and blood glucose were effective on the metabolic regulation of dyslipidemic rats. The activities of alkaline phosphatase, aspartate aminotransferase and alanine aminotransferase in serum were remarkably lower in the extract complexes (CSC-F-005) than in the dyslipidemic model. From the above results shows that CSC-F-005 extract complexes were effective on the improvement of the lipid metabolism in sera of dyslipidemic rats.

Keywords

References

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