Journal of Dental Rehabilitation and Applied Science (구강회복응용과학지)

Korean Academy of Stomatognathic Function and Occlusion (대한턱관절교합학회)
권호 표지

The Change of Facial Contouring after Unilateral Injection of Botulinum Toxin in Unilateral Masseter Hypertrophy Patients

편측성 교근비대 환자에서 편측 보툴리눔 독소 주사 후 안모의 변화

  • Cha, Yu-Rim (Department of Oral medicine, college of dentistry, Yonsei University) ;
  • Kim, Young-Gun (Department of Oral medicine, college of dentistry, Yonsei University) ;
  • Kim, Ji-Hyun (Department of Oral medicine, college of dentistry, Yonsei University) ;
  • Shim, Young-Joo (Department of Oral medicine, college of dentistry, Yonsei University) ;
  • Kim, Seong-Taek (Department of Oral medicine, college of dentistry, Yonsei University)
  • 차유림 (연세대학교 치과대학 구강내과학교실) ;
  • 김영건 (연세대학교 치과대학 구강내과학교실) ;
  • 김지현 (연세대학교 치과대학 구강내과학교실) ;
  • 심영주 (연세대학교 치과대학 구강내과학교실) ;
  • 김성택 (연세대학교 치과대학 구강내과학교실)
  • Received : 2011.05.12
  • Accepted : 2011.06.25
  • Published : 2011.06.30
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Abstract

Botulinum toxin type A (BoNT-A) is used for treating bilateral masseter hypertrophy since 1994. Recently there have been more clinical studies in this area, with some authors reporting that BoNT-A can reduce the size of the masseter muscle, as documented by photography, ultrasonography, computed tomography, and 3D(three dimensional) laser scan. However, earlier studies were only for bilateral masseter hypertrophy cases, not for unilateral masseter hypertrophy cases. The aim of this study was to use 3D laser scanning to evaluate changes in the external facial contour induced by unilateral BoNT-A injection. BoNT-A was injected into hypertrophic masseter muscle unilaterally in 10 patients with asymmetric masseter hypertrophy. The clinical effects of unilaterally injected BoNT-A were evaluated before the injection and 4, 8, and 12weeks after the injection using 3D laser scan. And the mean values of both sides (injection and non-injection sides) were compared with. At injection side, mean values of the volume and the bulkiest height at each time point diminished significantly between pre-injection and 4, 8, and 12weeks post-injection. At non-injection side, in contrast, mean values of the volume and the bulkiest height diminished also but less than that of injected side, and there was no statistical significance. In this limited study, we concluded that the unilaterally BoNT-A injection side showed greater mean values of the reduction of muscle volume than non-injection side at 4, 8, and 12 weeks after the injection.

교근비대 환자들은 그들의 각진 턱을 심미적으로 개선시키기 위해 교근 두께를 줄이기를 희망한다. 과거엔 수술적인 방법이 널리 알려져 왔지만 최근 양측으로 주사하는 보톡스 시술이 수술에 비해 덜 침습적이기에 그 대안으로 관심이 대두되고 있다. 이 연구의 목적은 기존의 양측성 교근비대에서 양측에 동량을 주사하는 방법과 달리 편측성 교근비대 환자에서 보툴리눔 독소를 편측으로만 주입 후 삼차원 레이저스캐너를 이용하여 안모의 부피변화를 측정하고자 하였다. 삼차원 레이저스캐너를 이용하여 술전에 편측성 교근비대 환자 10명의 하안모 부피를 측정한 후, 편측으로 보툴리눔 A형 독소 주사 25U이 주사되었다. 주사 4주, 8주, 12주 후 같은 방법으로 하안모의 부피를 측정한 뒤 술전의 삼차원 사진과 중첩하여 변화된 부피를 측정하였다. 주사한 쪽의 부피는 술전에 비해 보툴리눔 독소 주사 4주, 8주, 12주 후 현저히 줄어들었으며 통계학적으로 유의미한 결과를 보였다. 반면 주사안한 쪽의 부피는 특기할 변화가 없었다. 따라서 편측성 교근비대 환자에서 편측 보툴리눔 독소 주사 후 주사한 쪽의 부피가 현저히 감소하여 근육성 비대칭 환자에서 편측 보툴리눔 독소 주사가 심미적 개선에 도움을 줄 수 있을 것으로 사료된다.

Keywords

References

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