Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Effects of Houttuynia cordata Thunb Extract Inhibits on the Migration and Proliferation of Vascular Smooth Muscle Cell

어성초 추출물의 혈관 평활근 세포 이주 및 증식 억제 활성에 관한 연구

  • Han, Jung-Ho (Department of Bio medicine Institute, College of Natural Science, Hoseo University) ;
  • Park, Seon-Nam (Department of Bio medicine Institute, College of Natural Science, Hoseo University) ;
  • Yoon, Mi-So (Department of Bio medicine Institute, College of Natural Science, Hoseo University) ;
  • Choi, Ok-Byung (Department of Bio medicine Institute, College of Natural Science, Hoseo University)
  • 한정호 (호서대학교 자연과학부 생의학연구소) ;
  • 박선남 (호서대학교 자연과학부 생의학연구소) ;
  • 윤미소 (호서대학교 자연과학부 생의학연구소) ;
  • 최옥병 (호서대학교 자연과학부 생의학연구소)
  • Received : 2011.03.03
  • Accepted : 2011.05.23
  • Published : 2011.06.30
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Abstract

Houttuynia cordata Thunb.[H.cordata]belonging to Saururaceae, is a wild medicinal herb of perennial plants, and grows well in a place with a lot of shade and moisture. The medical action of H.cordata is reported to have an antitumer effect, toxicity-suppressive effect, antifungal effect, diuretic effect, and antioxidative action, but its effect hasn't been reported on cardiovascular diseases, such as ateriosclerosis and hypertension yet. This study intended to confirm the effect of the water extract of H.cordata on the migration and proliferation of rat aortic smooth muscle cells. Such results show that the water extract of H.cordata suppresses the migration and proliferation of rat aortic smooth muscle cells. It is believed that a useful clue will be offered later to the prevention of cardiovascular diseases such as ateriosclerosis and hypertension, and the development of their medicines on the basis of the fact.

Keywords

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