KSBB Journal

  • 제26권6호
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  • Pages.513-516
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  • 2011
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  • 1225-7117(pISSN)
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  • 2288-8268(eISSN)
한국생물공학회 (The Korean Society for Biotechnology and Bioengineering)
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김치로부터 분리한 Lactobacillus sakei K-7의 항충치 활성 특성

Anticariogenic Activities of Lactobacillus sakei K-7 Isolated from Kimchi

  • Moon, Jin-Seok (Department of Food Science and Technology, Chungbuk National University) ;
  • Ahn, Ji-Eun (Department of Food Science and Technology, Chungbuk National University) ;
  • Han, A-Reum (Department of Food Science and Technology, Chungbuk National University) ;
  • Heo, Jeong-Seon (Department of Food Science and Technology, Chungbuk National University) ;
  • Eom, Hyun-Ju (Department of Food Science and Technology, Chungbuk National University) ;
  • Shin, Chul-Soo (Advanced Protein Technologies Corp.) ;
  • Choi, Hye-Sun (National Academy of Agricultural Science, Rural Development Administration) ;
  • Han, Nam-Soo (Department of Food Science and Technology, Chungbuk National University)
  • 투고 : 2011.08.17
  • 심사 : 2011.10.22
  • 발행 : 2011.12.31
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초록

The occurrence of dental caries is mainly associated with oral pathogens, especially cariogenic Streptococcus mutans. The aim of this study was to isolate and characterize lactic acid bacterium showing inhibitory activity against cariogenic Streptococcus mutans. As results, an isolate with strong inhibitory activity was obtained from Kimchi and it was identified as Lactobacillus sakei by API and 16S rRNA gene analyses. This strain secreted an inhibitory compound in cell growth medium and the activity of the compound was completely disappeared by proteinase K revealing the fact that the compound is proteinous substance, bacteriocin. Optimal culture condition for bacteriocin production by Lb. sakei K-7 was at pH 7.5 and $37^{\circ}C$ for 18 h. Oral administration of this isolate may give anticariogenic and probiotic effects on hosts.

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참고문헌

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피인용 문헌

  1. 식용 식물추출물의 구강 세균에 대한 항균 활성 vol.63, pp.1, 2020, https://doi.org/10.3839/jabc.2020.008
  2. Inhibitory effect of n-hexane extract from Korean red ginseng marc against Streptococcus mutans causing dental caries vol.64, pp.4, 2021, https://doi.org/10.3839/jabc.2021.048