8 Years Follow-up of Complications after Maxillary Cyst Enucleation with Xenograft: Case Report

상악골낭종 적출술 후 이식된 이종골지지체의 술 후 8년 감염 증례

  • Lee, Eun-Young (Department of Oral and Maxillofacial Surgery, College of Medicine and Medical Research Institute, Chungbuk National University) ;
  • Kim, Kyoung-Won (Department of Oral and Maxillofacial Surgery, College of Medicine and Medical Research Institute, Chungbuk National University)
  • 이은영 (충북대학교 의과대학 구강악안면외과학교실, 의학연구소) ;
  • 김경원 (충북대학교 의과대학 구강악안면외과학교실, 의학연구소)
  • Received : 2011.03.29
  • Accepted : 2011.07.29
  • Published : 2011.09.30

Abstract

Bone grafts are becoming increasingly common in oral and maxillofacial surgery to improve bone healing procedures. Bovine bone as a xenograft is a representative osteoconductor and space filler; however, sometimes complications, such as infection and wound dehiscence are encountered with its use. We report the result of an eight-year follow-up of a xenograft case and processing methods of inorganic bovine bone along with a review of the literature. Xenograft ($LUBBOC^{(R)}$) was used in a cyst enucleation site of the maxilla, as a bone substitute and space filler. Inflammation and infection were defined several times as lack of osseous contact between the graft and host bone, caused by remodeling failure over an eight-year period. Pathologic findings of the xenograft revealed dead bony trabeculae with inflamed fibrous tissue and actinomycosis.

Keywords

References

  1. Lane JM, Sandnu HS. Current approaches to experimental bone grafting. Orthop Clin North Am 1987;18:213-25.
  2. Younger EM, Chapman MW. Morbidity at bone graft donor sites. J Orthop Trauma 1989;3:192-5. https://doi.org/10.1097/00005131-198909000-00002
  3. Friedlander GE. Current concepts review: Bone banking. J Bone Joint Surg 1982;64A:307-11.
  4. Rim JS, Kim SM, Ryu JJ, Kim HJ, Yi SE, Cho M. A clinico- radiographic study on effect of hap used after odontogenic cyst enucleation. J Korean Assoc Maxillofac Plast Reconstr Surg 1990;12:57-62.
  5. Lee DK, Min SK, Kwon KH, et al. Effect of decalcified freeze-dried allogeneic bone graft (DFDB) on the jaw defects after cyst enucleation. J Korean Assoc Maxillofac Plast Reconstr Surg 1999;21:360-5.
  6. Lee EY, Kim KW, Choi HW, Um IW, Chung HY. The histologic study of hBMP-I for immediate implant fixation. J Korean Assoc Maxillofac Plast Reconstr Surg 2004;30:316-22.
  7. Park JW. Evaluation of deprotenized bovine bone mineral as a bone graft substitute: a comparative analysis of basic characteristics of three commercially available bone substitute. J Korean Acad Periodontol 2005;5:863-75.
  8. Horowitz I, Bodner L. Use of xenograft bone with aspirated bone marrow for treatment of cystic defects of the jaws. Head Neck 1989;11:516-23. https://doi.org/10.1002/hed.2880110608
  9. Ahn JK, Kang MK, Park HS. Histopathologic Evaluation of Obliterating materials in the Temporal Dorsal Bullae of Rat. Korean J Otolaryngol 2007;50:391-8.
  10. Chappard D, Zhioua A, Grizon F, Basle MF, Rebel A. Biomaterials for bone filling: Comparisons between autograft, hydroxyapatitie and one highly purified bovine xenograft. Bull Assoc Anat (Nancy) 1993;77:59-65.
  11. Kim KS, Choi YS, Yeom KS, Joe KJ, Kim KS. Biologic changes of xenograft (LUBBO) in the surgical treatment of calcaneal fractures. J Korean Orthop Assoc 1999;34:699-706.
  12. Charalambides C, Beer M, Cobb AG. Poor results after augmenting autograft with xenograft (Surgibone) in hip revision surgery: a report of 27 cases. Acta Orthop 2005;76:544-9. https://doi.org/10.1080/17453670510041547
  13. Hartl A, Bitzan P, Wanivenhaus A, Kotz R. Faster integration of human allograft bone than of the bovine substitute Lubboc. Acta Orthop Scand 2004;75:217-20. https://doi.org/10.1080/00016470412331294485
  14. Cha SK, Kim IK, Oh SS, et al. Clinical study of cyst in the jaw. J Korean Assoc Oral Maxillofac Surg 2001;27:167-73.