Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
권호 표지
DOI QR코드

DOI QR Code

Effects of the blood chemistry of honeybee (Apis mellifera L.) venom on the Hanwoo calves

신생송아지의 봉독 처리가 혈액성상에 미치는 영향

  • Oh, Baeg-Young (Icheon-si Agricultural Technology Service Center) ;
  • Han, Sang-Mi (National Institute of Agricultural Science and Technology) ;
  • Oh, Young-Ik (Icheon-si Agricultural Technology Service Center) ;
  • Kim, Soon-Tae (Gyeongbuk Veterinary Service Laboratory)
  • 오백영 (이천시 농업기술센터) ;
  • 한상미 (농촌진흥청 농업과학기술원) ;
  • 오용익 (이천시 농업기술센터) ;
  • 김순태 (경상북도 가축위생시험소)
  • Received : 2011.03.10
  • Accepted : 2011.03.22
  • Published : 2011.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

This study was conducted to investigate effects of honeybee venom (Apis mellifera L. BV) on the calving, the growth performance and blood chemistry occurrence of Hanwoo calves. A total of twenty, a 3 day old male experimental calves were allocated into four groups, BV treated (0.05 mg/kg, 0.1 mg/kg and 0.2 mg/kg BV, n=5, respectively) and non-treated (n=5, Control) of Hanwoo calves in Icheon, Kyonggi province. Treatment of BV in calves increased body weight and weight gain during 60 days compared with control group. The concentrations of IgG in blood were significantly increased in BV groups compared with control at 60 days after treatment with BV. Cholesterol and glucose concentrations in BV group were significantly lower with control at 60 days. There were no differences in plasma biochemical components including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphate (AKLP), total protein, albumin, globuline, total bilirubin, creatinine, blood urea nitrogen (BUN) and $Ca^+$. In conclusion, the BV treatment had effect on growth, the score of the calf scours and blood biochemical profile.

Keywords

References

  1. 김두, 유영수, 유한상, 윤충근. 1990. 한우 송아지의 포유기간 중의 설사발생에 관한 연구. 대한수의학회지 30(2): 255-260.
  2. 김문호. 1992. 봉독요법과 봉침요법. 한국교육기획. 서울: 67-141.
  3. 정희승, 정근기, 장인석. 2009. 난황항체(IgY) 급여가 Holstein 송아지의 성장능력 및 면역관련 혈액 지표에 미치는 영향. 한국동물자원과학회지 51(4): 321-328.
  4. 최석화, 조성구, 강성수, 최향순, 박석천. 1999a. 생봉(Apis mellifera) 을 이용한 모돈의 무유증 치료효과. 한국양봉학회지 14(2): 119-126.
  5. 최석화, 조성구, 최향순, 강성수, 권영방. 1999b. 생봉독을 이용한 세균성 설사 자돈의 치료효과. 한국임상수의학회지 16(1): 150-154.
  6. 한상미, 이광길, 여주홍, 오백영, 김순태. 2010. 봉독 처리가 어미소의 번식효율과 송아지의 증체, 질병발생에 미치는 영향. 한국가축위생학회지 33(3): 287-292.
  7. 한상미, 이광길, 여주홍, 우순옥, 권해용. 2007. 봉독 간이정제법. 특허 제 10-0758814호.
  8. Abbadie C, Besson JM. 1994. Chronic treatments with aspirin or acetaminophen reduce both the development of polyarthritis and Fos-like immunoreactivity in rat lumbar spinal cord. Pain 57(1): 45-54. https://doi.org/10.1016/0304-3959(94)90106-6
  9. Curcio-Vonlanthen V, Schneider CH, Frutig K, Blaser K, Kalbacher H. 1997. Molecular parameters in melittin immunogenicity. J Pept Sci 3(4): 267-276. https://doi.org/10.1002/(SICI)1099-1387(199707)3:4<267::AID-PSC106>3.0.CO;2-7
  10. Girard F, Batisson I, Martinez G, Breton C, Harel J, Fairbrother JM. 2006. Use of virulence factor-specific egg yolk-derived immunoglobulins as a promising alternative to antibiotics for prevention of attaching and effacing Escherichia coli infections. FEMS Immunol Med Microbiol 46(3): 340-350. https://doi.org/10.1111/j.1574-695X.2005.00030.x
  11. Habermann E, Reiz KG. 1965. On the biochemistry of bee venom peptides, melittin and apamin. Biochem Z 343(2): 192-203.
  12. Han SM, Lee KG, Yeo JH, Hwang SJ, Chenoweth PJ, Pak SC. 2009b. Somatic cell count in milk of bee venom treated dairy cows with mastitis. J ApiProduct ApiMed Sci 1(3): 104-109. https://doi.org/10.3896/IBRA.4.01.4.02
  13. Han SM, Lee KG, Yeo JH, Hwang SJ, Jang CH, Chenoweth PJ, Pak SC. 2009a. Effects of bee venom treatment on growth performance of young pigs. Am J Chin Med 37(2): 253-260. https://doi.org/10.1142/S0192415X09006813
  14. Han SM, Lee KG, Yeo JH, OH BY, Kim BS, Lee W, Baek HJ, Kim ST, Hwang SJ, Pak SC. 2010. Effects of honeybee venom supplementation in drinking water on growth performance of broiler chickens. Poult Sci 89(11): 2396-2400. https://doi.org/10.3382/ps.2010-00915
  15. Kwon YB, Yoon SY, Kim HW, Roh DH, Kang SY, Ryu YH, Choi SM, Han HJ, Lee HJ, Kim KW, Beitz AJ, Lee JH. 2006. Substantial role of locus coeruleus-noradrenergic activation and capsaicin-insensitive primary afferent fibers in bee venom's anti-inflammatory effect. Neurosci Res 55(2): 197-203. https://doi.org/10.1016/j.neures.2006.03.003
  16. Lin JH, Rogers PAM. 1980. Acupuncture effects on the body's defense system; Veterinary Review. Vet Bull 50: 630- 640.
  17. Lin YC. 1987. Observation of therapeutic effects of acupuncture treatment in 170 cases of infantile diarrhea. J Tradit Chin Med 7(3): 203-204.
  18. McGuirk SM, Collins M. 2004. Managing the production, storage, and delivery of colostrum. Vet Clin North Am Food Anim Pract 20(3): 593-603. https://doi.org/10.1016/j.cvfa.2004.06.005
  19. Moon DO, Park SY, Lee KJ, Heo MS, Kim KC, Kim MO, Lee JD, Choi YH, Kim GY. 2007. Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharidestimulated BV2 microglia. Int Immunopharmacol 7(8): 1092-1010. https://doi.org/10.1016/j.intimp.2007.04.005
  20. Rauprich AB, Hammon HM, Blum JW. 2000. Influence of feeding different amounts of first colostrum on metabolic, endocrine, and health status and on growth performance in neonatal calves. J Anim Sci. 78(4): 896-908. https://doi.org/10.2527/2000.784896x
  21. Rowlands GJ, Manston R, Bunch KJ, Brookes PA. 2003. A genetic analysis of the concentrations of blood metabolites and their relationships with age and liveweight gain in young British Friesian bulls. Livest Prod Sci 10(1): 1-16.
  22. Rudenko SV, Nipot EE. 1996. Modulation of melittin-induced hemolysis of erythrocytes. Biokhimiia 61(12): 2116-2124.
  23. Vick JA, Shipman WH. 1972. Effects of whole bee venom and its fractions (apamin and melittin) on plasma cortisol levels in the dog. Toxicon 10(4): 377-380. https://doi.org/10.1016/0041-0101(72)90061-X
  24. Yoon SY, Roh DH, Kwon YB, Kim HW, Seo HS, Han HJ, Lee HJ, Beitz AJ, Lee JH. 2009. Acupoint stimulation with diluted bee venom (apipuncture) potentiates the analgesic effect of intrathecal clonidine in the rodent formalin test and in a neuropathic pain model. J Pain 10(3): 253-263. https://doi.org/10.1016/j.jpain.2008.09.002