Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • 제37권1호
  • /
  • Pages.67-71
  • /
  • 2011
  • /
  • 2234-7550(pISSN)
  • /
  • 2234-5930(eISSN)
대한구강악안면외과학회 (The Korean Association of Oral and Maxillofacial Surgeons)
권호 표지
DOI QR코드

DOI QR Code

하악에 발생한 저등급의 점액섬유육종: 증례보고

Low-grade myxofibrosarcoma in the mandible: a case report

  • 박지훈 (경북대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 최소영 (경북대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 권대근 (경북대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 김진수 (경북대학교 치의학전문대학원 구강악안면외과학교실)
  • Park, Ji-Hoon (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Choi, So-Young (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Kwon, Tae-Geon (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Kim, Chin-Soo (Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
  • 투고 : 2010.09.26
  • 심사 : 2011.01.19
  • 발행 : 2011.02.28
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Myxofibrosarcoma, also known as a myxoid variant of a malignant fibrous histiocytoma (MFH), is one of the most common sarcomas in the extremities of elderly people. The lesion is characterized by a high frequency of local recurrence but is uncommon in the head and neck regions. Low-grade myxofibrosarcoma, which is commonly misinterpreted as being benign, has a tendency for histological and biological progression in local recurrences, highlighting the importance of an accurate diagnosis and wide surgical excision of the primary lesion. We report a rare case of low-grade myxofibrosarcoma of the mandible located in the left mandibular body and angle area. The tumor was first diagnosed as a myxofibroma and was resected initially. After the final biopsy the patient underwent combined chemo-radiotherapy. The progress of the patent was uneventful until the one year follow up.

키워드

참고문헌

  1. Gugatschka M, Beham A, Stammberger H, Schmid C, Friedrich G. First case of a myxofibrosarcoma of the vocal folds: case report and review of the literature. J Voice 2010;24:374-6. https://doi.org/10.1016/j.jvoice.2008.10.008
  2. Nishimura G, Sano D, Hanashi M, Yamanaka S, Tanigaki Y, Taguchi T, et al. Myxofibrosarcoma of the hypopharynx. Auris Nasus Larynx 2006;33:93-6. https://doi.org/10.1016/j.anl.2005.07.004
  3. Wada T, Hasegawa T, Nagoya S, Kawaguchi S, Kaya M, Ishii S. Myxofibrosarcoma with an infiltrative growth pattern: a case report. Jpn J Clin Oncol 2000;30:458-62. https://doi.org/10.1093/jjco/hyd115
  4. Huang HY, Lal P, Qin J, Brennan MF, Antonescu CR. Lowgrade myxofibrosarcoma: a clinicopathologic analysis of 49 cases treated at a single institution with simultaneous assessment of the efficacy of 3-tier and 4-tier grading systems. Hum Pathol 2004;35:612-21. https://doi.org/10.1016/j.humpath.2004.01.016
  5. Angervall L, Kindblom LG, Merck C. Myxofibrosarcoma. A study of 30 cases. Acta Pathol Microbiol Scand A 1977;85A:127-40.
  6. Mentzel T, Calonje E, Wadden C, Camplejohn RS, Beham A, Smith MA, et al. Myxofibrosarcoma. Clinicopathologic analysis of 75 cases with emphasis on the low-grade variant. Am J Surg Pathol 1996;20:391-405.
  7. Sturgis EM, Potter BO. Sarcomas of the head and neck region. Curr Opin Oncol 2003;15:239-52. https://doi.org/10.1097/00001622-200305000-00011
  8. Nascimento AF, Bertoni F, Fletcher CD. Epithelioid variant of myxofibrosarcoma: expanding the clinicomorphologic spectrum of myxofibrosarcoma in a series of 17 cases. Am J Surg Pathol 2007;31:99-105. https://doi.org/10.1097/01.pas.0000213379.94547.e7
  9. Kummoona R. Central myxofibrosarcoma of the mandible treated by radical resection. Oral Surg Oral Med Oral Pathol 1975;39: 713-7. https://doi.org/10.1016/0030-4220(75)90031-6
  10. Lam PK, Trendell-Smith N, Li JH, Fan YW, Yuen AP. Myxofibrosarcoma of the sphenoid sinus. J Laryngol Otol 2002;116:464-6.
  11. Pomerantz JM, Sanfacon DG, Dougherty TP, Hanson S. Myxofibrosarcoma of the maxillary sinus. Del Med J 1982;54:147-52.
  12. Weiss SW, Enzinger FM. Myxoid variant of malignant fibrous histiocytoma. Cancer 1977;39:1672-85. https://doi.org/10.1002/1097-0142(197704)39:4<1672::AID-CNCR2820390442>3.0.CO;2-C
  13. Soper CP, Andrews PA, Bending MR, Singh L, Fisher C. Cervical myxofibrosarcoma in a renal allograft recipient treated with murine anti-CD3 monoclonal antibody therapy. Nephrol Dial Transplant 1998;13:1902-3. https://doi.org/10.1093/ndt/13.7.1902
  14. Merck C, Angervall L, Kindblom LG, Oden A. Myxofibrosarcoma. A malignant soft tissue tumor of fibroblastic-histiocytic origin. A clinicopathologic and prognostic study of 110 cases using multivariate analysis. Acta Pathol Microbiol Immunol Scand Suppl 1983;282:1-40.
  15. Kearney MM, Soule EH, Ivins JC. Malifnant fibrous histiocytoma: a retrospective study of 167 cases. Cancer 1980;45:167-78. https://doi.org/10.1002/1097-0142(19800101)45:1<167::AID-CNCR2820450127>3.0.CO;2-8

피인용 문헌

  1. Undifferentiated pleomorphic sarcoma of the mandible vol.46, pp.4, 2011, https://doi.org/10.5125/jkaoms.2020.46.4.282