Korean Journal of Clinical Pharmacy (한국임상약학회지)

Korean College Of Clinical Pharmacy (한국임상약학회)
권호 표지

Vancomycin Induced Lupus Flare in a Patient with Systemic Lupus Erythematosus: A Clinical Case Report

전신성 홍반성 루푸스 환자에서 Intravenous Vancomycin 투여로 인한 루푸스 활성기 증례 보고

  • Kim, Hyeon-Jin (Department of Pharmacy, Bucheon St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Yu-Jeung (Graduate School of Clinical Pharmacy, Sookmyung Women's University)
  • 김현진 (부천성모병원 약제팀) ;
  • 이유정 (숙명여자대학교 임상약학대학원)
  • Received : 2011.05.09
  • Accepted : 2011.07.07
  • Published : 2011.09.30
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Abstract

We report an unusual case of lupus flare induced by intravenous vancomycin in a patient with systemic lupus erythematosus. Due to methicillin resistant staphylococcus aureus in wound culture, intravenous vancomycin was administered to the patient. The patient had been on vancomycin for several days then she experienced fever, malar rash, and vomiting. Based on laboratory results, it was confirmed as lupus flare. Oral prednisolone was given to the patient for symptom control. However, when vancomycin was readministered, the patient had similar symptom to the previous one more intensively. Vancomycin was stopped then the patient became stable. This case report demonstrates that intravenous vancomycin may manifest as lupus flare in patients with systemic lupus erythematosus.

Keywords

References

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