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Early congenital syphilis presenting with skin eruption alone: a case report

  • Kim, Hak-Young (Department of Pediatrics, Chung-Ang University College of Medicine) ;
  • Kim, Beom-Joon (Department of Dermatology, Chung-Ang University College of Medicine) ;
  • Kim, Ji-Hyun (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Yoo, Byoung-Hoon (Department of Pediatrics, Chung-Ang University College of Medicine)
  • Received : 2011.03.25
  • Accepted : 2011.07.16
  • Published : 2011.12.15

Abstract

Congenital syphilis is one of the most well-known congenital infections, yet it remains a worldwide public health problem. Congenital syphilis can involve any organ system and present with various symptoms. However, early diagnosis of congenital syphilis is difficult because more than half of the affected infants are asymptomatic, and the signs in symptomatic infants may be subtle and nonspecific. Here, we report a case of congenital syphilis with only a skin rash, which led to a delay in diagnosis. This case indicates that congenital syphilis should be considered throughout early childhood.

Keywords

References

  1. Walker GJ, Walker DG. Congenital syphilis: a continuing but neglected problem. Semin Fetal Neonatal Med 2007;12:198-206. https://doi.org/10.1016/j.siny.2007.01.019
  2. Lugo A, Sanchez S, Sanchez JL. Congenital syphilis. Pediatr Dermatol 2006;23:121-3. https://doi.org/10.1111/j.1525-1470.2006.00194.x
  3. Park HJ. Clinical observation and statistical consideration of syphilis (2000-2007). Korean J Dermatol 2008;46:1344-52.
  4. Fan P, Fu M, Liao W, Luan Q, Hu X, Gao T, et al. Early congenital syphilis presented with exclusive bending pain of extremity: case report. J Dermatol 2007;34:214-6. https://doi.org/10.1111/j.1346-8138.2007.00253.x
  5. Simmank KC, Pettifor JM. Unusual presentation of congenital syphilis. Ann Trop Paediatr 2000;20:105-7. https://doi.org/10.1080/02724936.2000.11748117
  6. Woods CR. Syphilis in children: congenital and acquired. Semin Pediatr Infect Dis 2005;16:245-57. https://doi.org/10.1053/j.spid.2005.06.005
  7. Chakraborty R, Luck S. Syphilis is on the increase: the implications for child health. Arch Dis Child 2008;93:105-9. https://doi.org/10.1136/adc.2006.103515
  8. Sangtawesin V, Lertsutthiwong W, Kanjanapattanakul W, Khorana M, Horpaopan S. Outcome of maternal syphilis at Rajavithi hospital on offsprings. J Med Assoc Thai 2005;88:1519-25.
  9. Chudomirova K, Mihajlova E, Ivanov I, Lasarov S, Stefanova P. Congenital syphilis: missed opportunities for prenatal intervention. Sex Transm Infect 2002;78:224-5. https://doi.org/10.1136/sti.78.3.224
  10. Ferri FF. Ferri's clinical advisor 2011. Philadelphia: Mosby Elsevier, 2010: 431-60.
  11. Habif TP. Vesicular and bullous diseases. In: Habif TP, editor. Clinical dermatology. 5th ed. Edinburgh: Mosby Elsevier, 2009;635-70.
  12. Azimi P. Syphilis (Treponema pallidum). In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, editors. Nelson textbook of pediatrics. 18th ed. Philadelphia: Saunders Elsevier, 2007:1263-9.
  13. From the Centers for Disease Control and Prevention. Congenital syphilis: United States, 2000. JAMA 2001;286:529-30. https://doi.org/10.1001/jama.286.5.529

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