DOI QR코드

DOI QR Code

Change of Inorganic Component, Reducing Sugar, Catalpol and Benzo[α]pyrene Contents of Rehmannia glutinosa Libosch. var. purpurea Makino by Drying Methods

지황의 건조 방법에 따른 무기성분, 환원당, Catalpol 및 Benzo[α]pyrene의 함량 변화

  • Chang, Jun-Pok (Department of Oriental Pharmaceutical Science, Joongbu University) ;
  • Kil, Gi-Jung (Department of Oriental Pharmaceutical Science, Joongbu University) ;
  • Lee, Gun-Hee (Department of Oriental Pharmaceutical Science, Joongbu University) ;
  • Ji, Yoon-Sun (Department of Oriental Pharmaceutical Science, Joongbu University) ;
  • Kim, Bo-Ram (Department of Oriental Pharmaceutical Science, Joongbu University) ;
  • Kang, Ki-Hyun (Department of Oriental Pharmaceutical Science, Joongbu University) ;
  • Kim, Mee-Ree (Department of Food & Nutrition, Chungnam National University) ;
  • Song, Mi-Ran (Gumsan Ginseng & Medicinal Crop Experiment Station, CNARES) ;
  • Park, Jong-Yoon (Gumsan Ginseng & Medicinal Crop Experiment Station, CNARES) ;
  • Doh, Eun-Soo (Department of Oriental Pharmaceutical Science, Joongbu University)
  • 장준복 (중부대학교 한방제약과학과) ;
  • 길기정 (중부대학교 한방제약과학과) ;
  • 이건희 (중부대학교 한방제약과학과) ;
  • 지윤선 (중부대학교 한방제약과학과) ;
  • 김보람 (중부대학교 한방제약과학과) ;
  • 강기현 (중부대학교 한방제약과학과) ;
  • 김미리 (충남대학교 식품영양학과) ;
  • 송미란 (충남금산군농업기술센터) ;
  • 박종윤 (충남금산군농업기술센터) ;
  • 도은수 (중부대학교 한방제약과학과)
  • Received : 2011.11.11
  • Accepted : 2011.12.22
  • Published : 2011.12.30

Abstract

This experiment was carried out in order to collect the basic data on the standardization of the manufacturing process of Rehmannia glutinosa Libosch. var. purpurea Makino drying. By the drying methods of R. glutinosa, the content of water, inorganic components, reducing sugar, catalpol and benzo[${\alpha}$]pyrene were investigated. The water content was 15.6~17.2% when R. glutinosa was dried by cold-warm air moisture absorption drying method (CAMAD) at $60^{\circ}C$ during 6 days. Among of the inorganic components of R. glutinosa the K content was the most followed by P, Na, Ca and Mg. The reducing sugar content of R. glutinosa by the hot air drying method (HAD) was much more than that by the CAMAD. The catalpol content of R. glutinosa was not different by the drying temperature when it was dried by the CAMAD. The catalpol content of the large size tuber (about 50.0 g/unit) showed a tendency to increase from $60^{\circ}C$ until $70^{\circ}C$ drying temperature, but that of the small size tuber(about 4.0 g/unit) was decreased as being a trend as the drying temperature high when R. glutinosa was dried by the HAD, But the catalpol content R. glutinosa had a tendency to drop significantly at drying temperature above $80^{\circ}C$. The benzo[${\alpha}$]pyrene content was little detected when R. glutinosa was dried by both the SLD and the CAMAD, and the sampling by the HAD indicated within the scope of 5 ${\mu}g/kg$ which was the scope to regulate by Korean food and drug administration. In conclusion, it seemed that an appropriate drying temperature of R. glutinosa by the CAMAD and the HAD was about $60^{\circ}C$ and about $70^{\circ}C$, respectively, when we consider the catalpol content and benzo[${\alpha}$]pyrene detection in the manufacturing process of drying R. glutinosa.

Keywords

References

  1. Dubois MK, Gilles KA, Hamilton JK, Roberts PA and Smith F. (1956). Colorimetric method for determination of sugars and related substances. Analytical Chemistry. 28:350-356. https://doi.org/10.1021/ac60111a017
  2. Hong SP, Kim YC, Kim KH, Park JH and Park MK. (1993). Characteristic component of Rehmanniae radix preparata compared to Rehmanniae radix and Rehmanniae radix crudus. Analytical Science & Technology. 6:401-404.
  3. Hu SJ, Jin SH and Choi DG. (2008). Analysis of benzo[$\alpha$]pyrene in red ginseng beverage. Journal of Food Hygiene and Safety. 23:26-30.
  4. Hwang SY, Hwang BY, Choi WH, Jung HJ, Huh JD, Lee KS and Ro JS. (2001). Quantitative determination of 5-hydroxymethyl-2-furaldehyde in the Rehmanniae radix preparata samples at various processing stages. The Korean Society of Pharmacognosy. 32:116-120.
  5. Kim DS and Lee KB. (2009). Changes in benzo[a]pyrene content during processing of corn oil. Korean Journal of Food Preservation 16:75-81.
  6. Kim JW, Choi HY, Cho JH, Ahn DK, Yook CS, Byun MW, Lee J, Im MH and Kim DH. (2005). Studies on the stability of catalpol components and genotoxic safety of $\gamma$-irradiated Rehmanniae radix crude. The Korean Society of Pharmacognosy. 35:75-80.
  7. Kim NJ, Jung EA, Kim HJ, Sim SB and Kim JW. (2000). Quality evaluation of various dried roots of Rehmannia glutinosa. The Korean Society of Pharmacognosy. 31:130-141.
  8. Lee CK and Seo JM. (2004). Changes of the constituents in the Rehmanniae radix preparata during processing. Journal of Food Science and Nutrition. 33:1748-1752.
  9. Lee GB, Yang JB and Ko MS. (2006). Food Analysis. Yuhansa. Seoul, Korea. p. 175-176.
  10. Lee SY, Yean MH, Kim JS, Lee JH and Kang SS. (2011). Phytochemical studies on Rehmanniae Radix. The Korean Society of Pharmacognosy. 42:127-137.
  11. Morota T, Sasaki H, Nishimura H, Sugama K, Chin M and Mitsuhashi H. (1989). Two iridoid glycosides from Rehmannia glutinosa. Phytochemistry. 28:2149-2153. https://doi.org/10.1016/S0031-9422(00)97934-2
  12. Nishimura H, Sasaki H, Morota T, Chin M and Mitsuhashi H. (1989). Six iridoid glycosides from Rehmannia glutinosa. Phytochemistry. 28:2705-2709. https://doi.org/10.1016/S0031-9422(00)98072-5
  13. Nishimura H, Sasaki H, Morota T, Chin M and Mitsuhashi H. (1990). Six glycosides from Rehmannia glutinosa var. purpurea. Phytochemistry. 29:3303-3306. https://doi.org/10.1016/0031-9422(90)80204-T
  14. Oshio H and Inouye H. (1981). Iridoid glycosides of Rehmannia glutinosa. Phytochemistry. 21:133-138.
  15. Oshio H, Naruse Y and Inouye H. (1984). Quantitative analysis of iridoid glycoside of Rehmaniae radix. Shoyakugaku Zasshi. 35:291-294.
  16. Park NK, Kim SL, Hur HS and Park CH. (2002). Development of R. radix preparata with new variety "Jiwhang 1". The Korean Society of International Agriculture. 14:3-39.
  17. Sasaki H, Nishimura H, Chin M and Mitsuhashi H. (1989). Hydroxycinnamic acid esters of phenethylalcohol glycosides from Rehmannia glutinosa var. purpurea. Phytochemistry. 28:875-879. https://doi.org/10.1016/0031-9422(89)80134-7
  18. Shih CK, Son YJ and Lee YJ. (1999). Changes in the carbohydrate contents of Rehmanniae Radix during processing. The Korean Association of Herbology. 14:1-11.
  19. Shoyama Y, Matsumoto M and Nishioka I. (1986). Four caffeoyl glycosides from callus tissue of Rehmannia glutinosa. Phytochemistry. 25:1633-1636. https://doi.org/10.1016/S0031-9422(00)81224-8
  20. Shoyama Y, Matsumoto M and Nishioka I. (1987). Phenolic glycosides from diseased roots of Rehmannia glutinosa var. purpurea. Phytochemistry. 26:983-987. https://doi.org/10.1016/S0031-9422(00)82331-6
  21. Song DS, Woo KS, Seong NS, Kim KY, Jeong HS and Lee HB. (2007). Changes in quality of Rehmanniae radix preparata with heating conditions. Journal of Food Science and Nutrition. 36:773-778.
  22. Takagi K, Kimura M, Harada M and Otsuka Y. (1982). Pharmacology of medicinal herbs in east asia. Nanzando company Limited. Tokyo, Japan. p.74-75.
  23. Tang W and Eisenbrand G. (1992). Chinese drugs of plant origin. Springer-Verlag. Berlin, Germany. p.849-854.
  24. U.S. Environmental Protection Agency. (1998). 610-Polycyclic aromatic hydrocarbons: Methods for organic chemical analysis of municipal and industrial waste water. Washington, U.S. EPA. p. 849-854.
  25. You BR, Kim HR, Kim HJ, Lee JY, Lee SY, Song MR, Park JY and Kim MR. (2011). Catalpol content and antioxidant activities in various cultivars of Rehmannia glutinosa. Journal of Food Science and Nutrition. 40: 481-485.
  26. Zhang RX, Li MX and Jia ZP. (2008). Rehmannia glutinosa: Review of botany, chemistry and Pharmacology. The Journal of Ethnopharmacology. 117:199-214. https://doi.org/10.1016/j.jep.2008.02.018
  27. Zhu Mei-fen, Hong SP, Kim CS and Lee JH. (2003). Determina-tion methods of Rehmanniae Radix by HPLC. The Korean Association of Herbology. 18:203-209.

Cited by

  1. Variation of Bolting at Cultivation of Different Regions and Molecular Characterization of FLC homologs in Angelica gigas Nakai vol.20, pp.5, 2012, https://doi.org/10.7783/KJMCS.2012.20.5.359
  2. Quality Characteristics by Various Drying Methods in Ear Mushroom (Auricularia auricula-judae Quel.) vol.22, pp.6, 2014, https://doi.org/10.7783/KJMCS.2014.22.6.497