Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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Ancient schwannoma in oral cavity: a report of two cases

구강의 퇴행성 신경집종: 2예 보고

  • Kim, Na-Rae (Department of Pathology, Gachon University Gil Hospital) ;
  • Chung, Dong-Hae (Department of Pathology, Gachon University Gil Hospital) ;
  • Park, Dae-Song (Department of Oral and Maxillofacial Surgery, Gachon University Gil Hospital) ;
  • Kim, Dong-Woo (Department of Oral and Maxillofacial Surgery, Gachon University Gil Hospital) ;
  • Lee, Sang-Chil (Department of Oral and Maxillofacial Surgery, Gachon University Gil Hospital) ;
  • Kim, Sung-Yong (Department of Oral and Maxillofacial Surgery, Gachon University Gil Hospital) ;
  • Lim, Ho-Yong (Department of Oral and Maxillofacial Surgery, Gachon University Gil Hospital) ;
  • Yeom, Hak-Yeol (Department of Oral and Maxillofacial Surgery, Gachon University Gil Hospital) ;
  • Kim, Hyeon-Min (Department of Oral and Maxillofacial Surgery, Gachon University Gil Hospital)
  • 김나래 ;
  • 정동해 ;
  • 박대송 (가천대학교 의과대학 길병원 구강악안면외과) ;
  • 김동우 (가천대학교 의과대학 길병원 구강악안면외과) ;
  • 이상칠 (가천대학교 의과대학 길병원 구강악안면외과) ;
  • 김성용 (가천대학교 의과대학 길병원 구강악안면외과) ;
  • 임호용 (가천대학교 의과대학 길병원 구강악안면외과) ;
  • 염학열 (가천대학교 의과대학 길병원 구강악안면외과) ;
  • 김현민 (가천대학교 의과대학 길병원 구강악안면외과)
  • Received : 2011.07.24
  • Accepted : 2011.10.12
  • Published : 2011.12.31
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Abstract

This paper reports two cases of schwannomas arising from the oral cavity. One is an intraoral ancient schwannoma located at the left cheek, which evolved over a period of 13 years. The tumor was a well-demarcated buccal mass, which was located in the left lower first premolar area, with an obliterated the buccal vestibule, leaving the overlying mucosa intact. The second case was a central intraosseous schwannoma located from the left lower 1st molar periapical area to the left 3rd molar periapical area. Pathologically, the first mass was composed of the spindle shaped tumor cells with wavy nuclei beneath the fibroconnective tissue of the gingiva but second case mass was not. Occasional nuclear pleomorphism was observed but mitosis or necrosis was absent. There were Antoni A and B areas along with strong, diffuse staining with the S-100 protein. Ancient schwannomas were diagnosed. Schwannoma is a slow-growing benign tumor, and an ancient schwannoma that shows cellular atypism is a variant of a schwannoma caused by purely degenerative changes. To date, only limited cases of ancient schwannomas in the oral cavity have been reported.

Keywords

References

  1. Martins MD, Anunciato de Jesus L, Fernandes KP, Bussadori SK, Taghloubi SA, Martins MA. Intra-oral schwannoma: case report and literature review. Indian J Dent Res 2009;20:121-5. https://doi.org/10.4103/0970-9290.49059
  2. Yang SW, Lin CY. Schwannoma of the upper lip: case report and literature review. Am J Otolaryngol 2003;24:351-4. https://doi.org/10.1016/S0196-0709(03)00065-6
  3. Grabowski L. A rare case of schwannoma of the tongue. Otolaryngol Pol 2008;62:191-4. https://doi.org/10.1016/S0030-6657(08)70239-7
  4. Marx RE, Stern D. Oral and maxillofacial pathology: a rationale for treatment. 1st ed. Carol Stream: Quintessence Publishing; 2003: 408-11.
  5. Eversole LR, Howell RM. Ancient neurilemmoma of the oral cavity. Oral Surg Oral Med Oral Pathol 1971;32:440-3. https://doi.org/10.1016/0030-4220(71)90204-0
  6. Marks RK, Carr RF, Kreller AJ 3rd. Ancient neurilemoma of the floor of the mouth: report of a case. J Oral Surg 1976;34:731-5.
  7. McCoy JM, Mincer HH, Turner JE. Intraoral ancient neurilemoma (ancient schwannoma). Report of a case with histologic and electron microscopic studies. Oral Surg Oral Med Oral Pathol 1983;56:174-84. https://doi.org/10.1016/0030-4220(83)90285-2
  8. Dayan D, Buchner A, Hirschberg A. Ancient neurilemmoma (Schwannoma) of the oral cavity. J Craniomaxillofac Surg 1989;17:280-2. https://doi.org/10.1016/S1010-5182(89)80097-6
  9. Nakayama H, Gobara R, Shimamoto F, Kajihara H. Ancient schwannoma of the oral floor and ventricular portion of the tongue: a case report and review of the literature. Jpn J Clin Oncol 1996;26:185-8. https://doi.org/10.1093/oxfordjournals.jjco.a023205
  10. Ledesma C, Portilla J, Hernandez F, Garces M, Hernandez JC. Paraglandular ancient schwannoma. Med Oral 1999;4:398-402.
  11. Kim TW, Go CH, Song BU, Yang CM. A case of ancient schwannoma of the lingual nerve. Korean J Otolaryngol-Head Neck Surg 2000;43:559-61.(Korean)
  12. Chen CY, Wang WC, Chen CH, Chen YK, Lin LM. Ancient schwannoma of the floor of the mouth -A case report and review. Oral Oncol Extra 2006;42;281-5. https://doi.org/10.1016/j.ooe.2006.07.002
  13. Subhashraj K, Balanand S, Pajaniammalle S. Ancient schwannoma arising from mental nerve. A case report and review. Med Oral Patol Oral Cir Bucal 2009;14:E12-4.
  14. Amirchaghmaghi M, Salehinejad J, Basirat M, Delavarian Z, Javadzade A, Forouzanfar A. Gingival ancient schwannoma: Review of literature and a case report. J Applied Sci 2010;10:3137- 40. https://doi.org/10.3923/jas.2010.3137.3140
  15. Bilici S, Akpınar M, Yigit O, Günver F. Ancient schwannoma of the tongue: a case report. Kulak Burun Bogaz Ihtis Derg 2011;21: 234-6. https://doi.org/10.5606/kbbihtisas.2011.033
  16. Humber CC, Copete MA, Hohn FI. Ancient schwannoma of upper lip: case report with distinct histologic features and review of the literature. J Oral Maxillofac Surg 2011;69:e118-22. https://doi.org/10.1016/j.joms.2010.11.024
  17. Karaca CT, Habesoglu TE, Naiboglu B, Habesoglu M, Oysu C, Egeli E, et al. Schwannoma of the tongue in a child. Am J Otolaryngol 2010;31:46-8. https://doi.org/10.1016/j.amjoto.2008.09.010
  18. Lopez-Carriches C, Baca-Perez-Bryan R, Montalvo-Montero S. Schwannoma located in the palate: clinical case and literature review. Med Oral Patol Oral Cir Bucal 2009;14:e465-8.
  19. Gallego L, Junquera L, Rodriguez-Recio C, Fresno MF. Intraosseous mandibular schwannoma mimicking an odontogenic keratocyst, with a postsurgical pathological fracture. J Laryngol Otol 2009;123:560-2. https://doi.org/10.1017/S0022215108002934
  20. Flickinger FW, Lozano RL, Yuh WT, Sachs MA. Neurilemoma of the tongue: MR findings. J Comput Assist Tomogr 1989;13:886-8. https://doi.org/10.1097/00004728-198909000-00025
  21. Weiss SW, Goldblum JR. Benign tumors of peripheral nerves. In: Weiss SW, Goldblum JR, eds. Enzinger and Weiss's Soft Tissue Tumors. 5th ed. Philadelphia: Mosby; 2008:825-902.

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