Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
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MR Imaging Features of Acute Enterovirus 71 Encephalitis in a Patient with Hand-Foot-Mouth Disease: A Case Report

수족구병에서 합병된 장바이러스 71에 의한 급성 뇌염의 자기공명영상 소견

  • Park, Byung-Sa (Department of Radiology, Eulji University Hospital) ;
  • Yu, In-Kyu (Department of Radiology, Eulji University Hospital) ;
  • Lee, Byung-Hee (Department of Radiology, Eulji University Hospital)
  • 박병사 (대전을지대학병원 영상의학과) ;
  • 유인규 (대전을지대학병원 영상의학과) ;
  • 이병희 (대전을지대학병원 영상의학과)
  • Published : 2011.02.01
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Abstract

We report here on the MR findings of the first Korean case of hand-foot-mouth disease(HFMD) complicated by acute enterovirus 71 (EV 71) encephalitis in a 33-month old girl. Conventional MR images of the patient showed the increased signal intensity(SI) on a T2-weighted image (WI) at the posterior aspect of the medulla, the pontine tegmen, the bilateral dentate nuclei of the cerebellum and the midbrain. There was no evidence of abnormal SI or contrast enhancement at the same areas of the brain on the pre- and post-contrast T1-WI. The diffusion weighted images (DWI) also revealed the bilateral symmetrical strong high SI at the posterior aspect of the medulla and pontine tegmen and there was low SI at the same areas on the apparent diffusion coefficient(ADC) map. DWI in addition to the conventional MR imaging may be helpful for the early detection of acute EV 71 encephalitis in a patient with HFMD.

본 연구는 수족구병을 앓고 있는 33개월 된 여아에서 장바이러스 71에 의한 감염으로 합병된 급성 뇌염의 자기공명영상 소견을 우리나라 최초로 보고한다. 자기공명영상의 T2 강조영상에서 연수와 뇌교의 후방부, 양측 소뇌 치상핵, 그리고 중뇌에 고신호가 나타났고, T1 강조영상에서는 신호 변화가 보이지 않았으며, 조영 증강은 관찰되지 않았다. 또한, 동시에 시행한 확산강조영상에서 연수와 뇌교의 후방부에 뚜렷한 고신호가 관찰되었으며, 겉보기확산계수(apparent diffusion coefficient, 이하 ADC) map에서는 저신호로 보였다. 자기공명영상에 추가로 시행하는 확산강조영상은 수족구병에서 합병된 장바이러스 71에 의한 급성 뇌염의 이환 부위 평가에 도움을 줄 것이다.

Keywords

References

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