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Antimicrobial Activity and Mechanism of Supercritical Fluids

초임계 유체의 미생물 불활성화 특성 및 기작

  • Mun, Sungmin (World Class University (WCU) Program of Chemical Convergence for Energy & Environment (C2E2), School of Chemical and Biological Engineering, College of Engineering, Seoul National University) ;
  • Kim, Jungchan (World Class University (WCU) Program of Chemical Convergence for Energy & Environment (C2E2), School of Chemical and Biological Engineering, College of Engineering, Seoul National University) ;
  • Lee, Youn-Woo (World Class University (WCU) Program of Chemical Convergence for Energy & Environment (C2E2), School of Chemical and Biological Engineering, College of Engineering, Seoul National University) ;
  • Yoon, Jeyong (World Class University (WCU) Program of Chemical Convergence for Energy & Environment (C2E2), School of Chemical and Biological Engineering, College of Engineering, Seoul National University)
  • 문성민 (서울대학교 화학생물공학부) ;
  • 김정찬 (서울대학교 화학생물공학부) ;
  • 이윤우 (서울대학교 화학생물공학부) ;
  • 윤제용 (서울대학교 화학생물공학부)
  • Received : 2011.06.21
  • Accepted : 2011.08.22
  • Published : 2011.10.10

Abstract

Recently, there is growing interests in the application of supercritical fluids for food and medical fields since supercritical fluids ($CO_2$ and $N_2O$) have known to be safe and effective as a non-thermal sterilization technique. Although supercritical fluids have been investigated for various kinds of products, they have not yet been used in common currency due to their lack of knowledge related to the antimicrobial activity or detailed mechanisms. In this review paper, we summarized the characteristics, antimicrobial activity and mechanisms, important factors, and applicability of supercritical fluids to help the investigation and commercialization of supercritical fluids sterilization technique.

안전하고 미생물 불활성화 능력이 높은 초임계 유체(이산화탄소 및 일산화이질소)는 최근 식품 및 의료 분야 등에서 비가열 살균기술로 응용 가능성이 높아 관심이 증대되고 있다. 하지만 초임계 유체를 이용한 많은 응용 연구에도 불구하고 초임계 유체 살균기술의 살균 성능 및 기작에 대한 이해 부족으로 아직 널리 활용되고 있지 못하다. 따라서 본 글에서는 기존 연구를 중심으로 초임계 유체 특성, 미생물 불활성화 특성과 기작, 주요 영향 인자, 응용 분야 등에 대해서 정리 및 검토하여 초임계 유체 살균기술의 연구 및 상용화에 도움이 되고자 한다.

Keywords

Acknowledgement

Supported by : 한국과학재단

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