Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
권호 표지
DOI QR코드

DOI QR Code

Optical and Thermal Characteristic Studies of Cartilage by Laser Irradiation

레이저에 의한 연골의 광학적 열적 특성변화 연구

  • Lee, Yeon-Ui (Department of Biomedical Engineering, College of Medical Science, Catholic University of Daegu) ;
  • Youn, Jong-In (Department of Biomedical Engineering, College of Medical Science, Catholic University of Daegu)
  • 이연의 (대구가톨릭대학교 의료과학대학 의공학과) ;
  • 윤종인 (대구가톨릭대학교 의료과학대학 의공학과)
  • Received : 2011.07.04
  • Accepted : 2011.09.02
  • Published : 2011.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

Laser cartilage reshaping(LCR) is a promising method for reshaping cartilage by using laser irradiation to maintain permanently modifies its shape. However this method has not been fully understood due to the limited scientific researches. The purpose of this study is to analyze optical and thermal characteristics of cartilage during laser irradiation. After analyzing Monte Carlo simulation for the comparison of laser fluence distributions with different laser wavelengths the characterization of the spectral changes during Nd:YAG laser(${\lambda}$ = 1444 nm) irradiation was investigated in the ranges of 900-1700 nm with double integrating spheres. The surface temperature distribution changes during laser irradiation were investigated with an infrared camera. The quantitative measurements of optical and thermal characteristics in cartilage after laser irradiation were correlated with the transition of water flux(from bound to free water) and this study may be useful for better understanding of biophysical transformation phenomena in cartilage after laser heating.

Keywords

References

  1. F.F. Jaffe, H.J. Mankin, H. Weiss, and A. Zarins,"Water binding in the articular cartilage of rabbits," J. Bone Joint Surg. Am., vol. 56, pp. 1031-1039, 1974. https://doi.org/10.2106/00004623-197456050-00014
  2. E. Sobol, A Sviridov, A Omel'chenko, V. Bagratashvili, M. kitai, and S.E. Harding, N. Jones, K. Jumel, M. Mertig, W. Pompe, Y. Ovchinnikov, A. Shekhter, and V. Svistushkin, "Laser reshaping of cartilage," Biotechnol. Genet. Eng. Rev., vol. 17, pp. 553-631, 2000. https://doi.org/10.1080/02648725.2000.10648005
  3. S.C. Jiang, and X.X. Zhang, "Effects of dynamic change of tissue properties during laser-induced interstitial thermotherapy," Lasers Med. Sci., vol. 19, no. 4, pp. 197-202, 2005. https://doi.org/10.1007/s10103-004-0324-8
  4. R. Wright, D.E. Protsenko, S. Diaz, K. Ho and, B. Wong, "Shape retention in porcine and, rabbit nasal septal cartilage using saline bath immersion and Nd:YAG laser irradiation," Lasers Surg. Med., vol. 37, pp. 201-209, 2005. https://doi.org/10.1002/lsm.20212
  5. C. Li, D.E. Protsenko, A. Zemek, Y.S. Chae and, B. Wong, "Analysis of Nd:YAG laser-mediated thermal damage in rabbit nasal septal cartilage," Lasers Surg. Med., vol. 39, pp. 451-457, 2007. https://doi.org/10.1002/lsm.20514
  6. E. Helidonis, E. Sobol, G. Kavvalos, J. Bizakis, and P. Christodoulou, G. Velegrakis, "Laser shaping of composite cartilage grafts," Am. J. Otolaryngol., vol. 14, no. 6, pp. 410-412, 1993. https://doi.org/10.1016/0196-0709(93)90115-N
  7. E.N. Sobol, Phase transformations and ablation in lasertreated solids, New York : John Wiley, 1995, pp. 316-321.
  8. E. Sobol, A. Sviridov, V. Bagratashvili, A. Omel'chenko, M. Kitai, and V. Popov, "Mechanism of laser-induced stress relaxation in cartilage," Proc SPIE, vol. 2975, pp. 310-315, 1997.
  9. B. Wong, T. Milner, B. Anvari, A. Sviridov, A. Omel'chenko, V. Bagratashvili, E. Sobol, and J. S. Nelson,"Thermooptical response of cartilage during feedback-controlled laser-assisted reshaping," Proc SPIE, vol. 2970, pp. 380-391, 1997.
  10. M.R. Homicz, K.B. McGowan, L.M. Lottman, G. Beh, R.L. Sah and, D. Watson, "A compositional analysis of human nasal septal cartilage," Arch. Facial Plast Surg., vol. 5, no. 1, pp. 53-58, 2003. https://doi.org/10.1001/archfaci.5.1.53
  11. L.P. Cartner, and J.L. Hiatt, Cartilage and bone, Color textbook of histology. 3rded, Philadelphia: Saunders elsevir, 2007, pp. 131-187.
  12. 윤진희, 윤종인, "Evaluation of effective cartilage reshaping using Nd:YAG laser(l = 1444 nm)," Korean society of medical & biological engineering, vol. 31 no. 6, pp. 472-480, 2010.
  13. Y. Chae, D. Protsenko, P.K. Holden, C. Chlebicki, and B.J. Wong, "Thermoforming of tracheal cartilage: viability, shape change, and mechanical behavior," Lasers Surg. Med. vol. 40, no. 8, pp. 550-61, 2008. https://doi.org/10.1002/lsm.20666
  14. N. Jones, A. Sviridov, E. Sobol, A. Omelchenko, and J. Lowe, "A prospective randomised study of laser reshaping of cartilage in vivo," Lasers Med. Sci., vol. 16, no. 4, pp. 284-290, 2001. https://doi.org/10.1007/PL00011365
  15. D.W. Ebert, C. Roberts, S.K. Farrar, W.M. Johnston, A.S. Litsky, and A.L. Bertone, "Articular cartilage optical properties in the spectral range 300-850 nm," J. Biomed. Optics, vol. 3, no. 3, pp. 326-333, 1998. https://doi.org/10.1117/1.429893
  16. I.S. Choi, "Laser cartilage reshaping," Korean J Otorhinolaryngol- Head Neck Surg., vol. 52, pp. 296-301, 2009. https://doi.org/10.3342/kjorl-hns.2009.52.4.296
  17. G.A. Velegrakis, C.E. Papadakis, A.A. Nikolidakis, E.P. Prokopakis, M.E. Volitakis, and I. Naoumidi, "In vitro ear cartilage shaping with carbon dioxide laser: An experimental study," Ann. Otol. Rhinol. Laryngol., vol. 109, pp. 119-28, 2000. https://doi.org/10.1177/000348940010900201
  18. M.L. Kaiser, A.M. Karam, A. Sepehr, H. Wong, L.H. Liaw, and D.E. Vokes, "Cartilage regeneration in the rabbit nasal septum," Laryngoscope, vol. 116, no. 10, pp. 1730-1734, 2006. https://doi.org/10.1097/01.mlg.0000231430.81255.75
  19. S. Mordon, T. Wang, L. Fleurisse, and C. Creusy, "Laser cartilage reshaping in an in vivo rabbit model using a 1.54 micron Er:Glass laser," Lasers Surg. Med., vol. 34, no. 4, pp. 315-22, 2004. https://doi.org/10.1002/lsm.20029
  20. H.C. Lee, and Y.P. Kim, "Simultaneous dual-wavelength oscillation at 1357 nm and 1444 nm in a Kr-flashlamp pumped Nd:YAG laser," Optics Communications, vol. 281, no. 17, pp. 4455-4458, 2008. https://doi.org/10.1016/j.optcom.2008.05.028
  21. J.I. Youn, "A comparison of wavelength dependence for Laserassisted lipolysis effect using Monte Carlo simulation," Journal of the Optical Society of Korea, vol. 12, pp. 267-271, 2009.
  22. L. Wang, S.L. Jacques, and L. Zheng, "MCML-Monte Carlo modeling of light transport in multi-layered tissues," Comput. Methods Programs Biomed., vol. 47, no. 2, pp. 131-146, 1995. https://doi.org/10.1016/0169-2607(95)01640-F
  23. 임수현, 구철희, "Monte Carlo 시뮬레이션을 이용한 생체조직내의 광선량 측정", J. Biomed. Eng. Res., vol. 20, no. 2, pp. 199-204, 1999.
  24. M. Hammer, A. Roggan, D. Schweitzer, and G. Muller, "Optical properties of ocular fundus tissues-an in vitro study using the double-integrating-sphere technique and inverse Monte Carlo simulation," Phys. Med. Biol., vol. 40, no. 6, pp. 963-978, 1995. https://doi.org/10.1088/0031-9155/40/6/001
  25. S. Prahl, "Inverse Adding-Doubling for optical property measurement," Oregon Medical Laser Center, 2007.
  26. G. Spahn, H. Plettenberg, H. Nagel, E. Kahl, H.M. Klinger, T. Mückley, M.unther, G.O. Hofmann, and J.A. Mollenhauer, "Evaluation of cartilage defects with near-infrared spectroscopy( NIR): An ex vivo study," Med. Eng. Phys., vol. 30, no. 3, pp. 285-292, 2008. https://doi.org/10.1016/j.medengphy.2007.04.009
  27. P. Taroni, D. Comelli, A. Pifferi, A. Torricelli, and R. Cubeddu, "Absorption of collagen: effects on the estimate of breast composition and related diagnostic implications," J. Biomed. Opt., vol. 12, no. 1, pp. 01421, 2007.
  28. Y. Chae, D. Protsenko, E.J. Lavernia and B.J.F. Wong, "Effect of water content on enthalpic relaxations in porcine septal cartilage," J. Therm. Anal. and Calorim., vol. 95, pp. 937-943, 2009. https://doi.org/10.1007/s10973-007-8782-4
  29. A. Sviridov, E. Sobol, N. Jones and, J. Lowe, "The effect of Holmium laser radiation on stress, temperature and structure of cartilage," Lasers Med. Sci., vol. 13, no. 1, pp. 73-77, 1998. https://doi.org/10.1007/BF00592962
  30. V.N. Bagratashvili, E.N. Sobol, A.P. Sviridov, V.K. Popov, A.I. Omel'chenko, and, S.M. Howdle, "Thermal and diffusion processes in laser-induced stress relaxation and reshaping of cartilage," J. Biomechanics, vol. 30, no. 8, pp. 813-817, 1997. https://doi.org/10.1016/S0021-9290(97)00028-6
  31. N. Ignatieva, O. Zakharkina, G. Leroy, E. sobol, N. Vorobieva, and S. Mordon, "Molecular processes and structural alterations in laser reshaping of cartilage," Laser Phys. Lett., vol. 4, no. 10, pp. 749-753, 2007. https://doi.org/10.1002/lapl.200710042
  32. I.S. Choi, Y.S. Chae, A. Zemek, D.E. Protsenko, and B. Wong, "Viability of human septal cartilage after 1.45 microm diode laser irradiation," Lasers Surg. Med., vol. 4, no. 8, pp. 562-569, 2008.