De Novo 점막하 침윤 대장암으로 진단된 3 mm 크기의 무경성 미소 용종

De Novo Submucosal Colorectal Cancer in a 3 mm Sessile Polyp

  • 구소미 (순천향대학교 의과대학, 소화기연구소) ;
  • 김진오 (순천향대학교 의과대학, 소화기연구소) ;
  • 김현건 (순천향대학교 의과대학, 소화기연구소) ;
  • 이태희 (순천향대학교 의과대학, 소화기연구소) ;
  • 전성란 (순천향대학교 의과대학, 소화기연구소) ;
  • 진소영 (순천향대학교 의과대학, 소화기연구소) ;
  • 이준성 (순천향대학교 의과대학, 소화기연구소)
  • Koo, So-My (Institute for Digestive Research, Soonchunhyang University College of Medicine) ;
  • Kim, Jin-Oh (Institute for Digestive Research, Soonchunhyang University College of Medicine) ;
  • Kim, Hyun-Gun (Institute for Digestive Research, Soonchunhyang University College of Medicine) ;
  • Lee, Tae-Hee (Institute for Digestive Research, Soonchunhyang University College of Medicine) ;
  • Jeon, Seong-Ran (Institute for Digestive Research, Soonchunhyang University College of Medicine) ;
  • Jin, So-Young (Institute for Digestive Research, Soonchunhyang University College of Medicine) ;
  • Lee, Joon-Seong (Institute for Digestive Research, Soonchunhyang University College of Medicine)
  • 발행 : 2011.02.27

초록

대장암의 95~100%는 샘종-샘암종 과정을 거치며, 직접 발생 과정을 거친 de novo 대장암은 비교적 드물다. 일반적으로 de novo 대장암은 암조직 주변에 샘종이 동반되지 않는 경우로 정의되며, 샘종-샘암종의 단계가 생략되면서 샘종에서 기원한 암보다 상대적으로 더 빠르게 성장하며 침윤 정도도 더 깊을 수 있다. De novo 대장암은 평탄형이나 함몰형 육안 소견으로 보고되지만 아직까지 그 육안 소견이 정립되어 있지 않으며 융기형을 포함하여 다양한 형태로 관찰될 수 있다. 저자들은 내시경 점막절제술로 제거한 3 mm 크기의 무경성 미소 대장 용종의 병리 조직 검사에서 점막하층을 침범한 de novo 대장암을 진단하여서 이를 보고한다.

The majority of colorectal carcinomas (95~100%) are thought to arise from adenomas. Yet colorectal carcinomas may rarely arise de novo. The popular definition of de novo carcinoma is that the lesion should consist exclusively of a carcinoma histologically and contain no adenomatous elements. Without an adenoma-carcinoma sequence, de novo carcinomas have a much higher rate of submucosal invasion, despite their small size. Their speed of growth is thought to be rapid. Some studies have shown that de novo carcinomas might arise as a macroscopically flat or depressed lesion, rather than a protruded one. However, the typical macroscopic findings of de novo carcinomas have not been established. They might be variable macroscopically and include a protruded type. We report a case of de novo colorectal carcinoma that invaded the submucosal layer involving a minute sessile polyp only 3 mm in diameter, which was removed by endoscopic mucosal resection.

키워드

참고문헌

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