Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthetic Approaches to Natural Antioxidant Benzastatin E, F and G Analogues

  • Le, Thanh Nguyen (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Yang, Su-Hui (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Khadka, Daulat Bikram (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Cho, Suk-Hee (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Zhao, Chao (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Cho, Won-Jea (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
  • Received : 2011.09.16
  • Accepted : 2011.10.13
  • Published : 2011.12.20
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Abstract

For synthesis of benzastatin E, F and G analogues, the indole-2-carbaldehydes with or without substituents at C-5 position were prepared as key intermediates. Several synthetic attempts to achieve benzastatin E-G analogues were suggested using the indole-2-carbaldehyde intermediates.

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References

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