Journal of the Korean Society of Radiology (대한영상의학회지)

The Korean Society of Radiology (대한영상의학회)
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Islet Cell Tumors of the Pancreas: A Variety of Multiphase Dynamic Imaging Findings with Pathologic Correlations Focusing on Nonfunctioning Tumors and Insulinomas

췌장 도세포종양: 다양한 다상역동영상소견과 병리소견과의 상호 관련성-비기능성 종양과 인슐린종을 중심으로

  • Hong, Yoo-Jin (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Yu, Jeong-Sik (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Park, Chan-Il (Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kwon, Ji-Eun (Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Chung, Jae-Joon (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Joo-Hee (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Ki-Whang (Department of Diagnostic Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine)
  • 홍유진 (연세대학교 의과대학 강남세브란스병원 영상의학과) ;
  • 유정식 (연세대학교 의과대학 강남세브란스병원 영상의학과) ;
  • 박찬일 (연세대학교 의과대학 강남세브란스병원 병리과) ;
  • 권지은 (연세대학교 의과대학 강남세브란스병원 병리과) ;
  • 정재준 (연세대학교 의과대학 강남세브란스병원 영상의학과) ;
  • 김주희 (연세대학교 의과대학 강남세브란스병원 영상의학과) ;
  • 김기황 (연세대학교 의과대학 강남세브란스병원 영상의학과)
  • Received : 2010.07.30
  • Accepted : 2010.08.24
  • Published : 2010.11.01
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Abstract

Islet cell tumors (ICTs) are rare pancreatic neoplasms of neuroendocrine origin, posing a diagnostic challenge to radiologists. We illustrated a spectrum of features of pancreatic ICTs that could be found on multiphase dynamic CT or MRI, and elucidated the histopathologic characteristics by determining the contrast enhancement pattern of the lesions. Various enhancement patterns were dependant on the internal composition of the tumor, that is, the proportion of vascular densities for early enhancement and non-hypervascular interstitial tissue for late enhancement regardless of the size or functional behavior. This knowledge of the imaging-pathologic spectrum of ICTs could be helpful for the proper differential diagnosis from other pancreatic tumors.

췌장도세포종양은 췌장의 내분비세포에서 발생하는 드문 종양으로 다양한 영상소견을 보이기 때문에 종종 진단에 어려움을 겪는다. 이 논문에서는 다상역동컴퓨터단층촬영술과 자기공명영상에서 보이는 췌장도세포종양의 다양한 영상소견을 살펴보고 조영증강패턴을 병리소견과 연관시켜 보고자 하였다. 다양한 조영증강패턴은 종양의 내부구성 요소에 따라 다르며 이른 시기의 조영증강은 종양 내부의 혈관 밀도에 의해 결정되고 늦은 시기의 조영증강은 혈관이 없는 세포외간질조직의 양에 의해 결정된다. 췌장도세포종양의 다양한 영상소견과 병리소견의 연관성을 앎으로써 다른 췌장종양과 감별하는데 도움이 될 것으로 생각한다.

Keywords

References

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