Clinical Endoscopy

  • 제41권3호
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  • Pages.155-158
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  • 2010
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  • 2234-2400(pISSN)
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  • 2234-2443(eISSN)
대한소화기내시경학회 (The Korean Society of Gastrointestinal Endoscopy)
권호 표지

식도에서 발견된 이소성 피지선 1예

A Case of Ectopic Sebaceous Glands in the Esophagus

  • 박형복 (관동대학교 의과대학 내과학교실) ;
  • 조현근 (관동대학교 의과대학 내과학교실) ;
  • 김유진 (관동대학교 의과대학 내과학교실) ;
  • 박경석 (관동대학교 의과대학 내과학교실) ;
  • 우명렬 (관동대학교 의과대학 내과학교실) ;
  • 고근준 (관동대학교 의과대학 내과학교실) ;
  • 오화은 (관동대학교 의과대학 병리학교실) ;
  • 이상엽 (관동대학교 의과대학 병리학교실)
  • Park, Hyung-Bok (Department of Internal Medicine, College of Medicine, Kwandong University) ;
  • Cho, Hyeon-Geun (Department of Internal Medicine, College of Medicine, Kwandong University) ;
  • Kim, Yu-Jin (Department of Internal Medicine, College of Medicine, Kwandong University) ;
  • Park, Kyung-Suk (Department of Internal Medicine, College of Medicine, Kwandong University) ;
  • Woo, Myoung-Lyeol (Department of Internal Medicine, College of Medicine, Kwandong University) ;
  • Ko, Geun-Jun (Department of Internal Medicine, College of Medicine, Kwandong University) ;
  • Oh, Hwa-Eun (Department of Pathology, College of Medicine, Kwandong University) ;
  • Yi, Sang-Yeop (Department of Pathology, College of Medicine, Kwandong University)
  • 투고 : 2010.05.14
  • 심사 : 2010.07.14
  • 발행 : 2010.09.30
⟨ 이전 논문 다음 논문 ⟩

초록

42세 남자가 건강 검진 목적으로 시행한 상부위장관 내시경에서 중부 및 하부 식도에 황색의 작은 반성(plaques) 병변들이 수십여 개 관찰되어 생검을 하였고 조직병리 검사에서 식도에 발생한 이소성 피지선으로 밝혀졌다. 식도에서 이소성 피지선이 발견되는 경우는 드물며 아직 정확한 발생학적 기원에 대해서도 명확히 밝혀지지 않았다. 일부 보고에서 식도암 또는 위암에서 이소성 피지선이 동반된 경우가 있었으나 이소성 피지선 자체로부터 악성 종양이 발생한 증례는 아직 보고된 바 없다. 본 증례는 1년 후 내시경 및 추적 조직 검사를 하여 특이 변화가 없는 것을 확인하였고, 항 케라틴 14 면역 염색을 하여 이소성 피지선이 식도 상피 세포의 화생의 결과라는 가설에 대해 검증하였다.

A 42-year-old man without any signs or symptoms of illness underwent esophagogastroduodenoscopy (EGD) for a routine health check up. On esophagogastroduodenoscopy, multiple small and yellowish mucosal plaques were detected in the mid to distal esophagus. These plagues proved to be ectopic sebaceous glands of the esophagus according to the histologic examination. On the immunohistochemical staining with anti-Keratin 14, the basal cells and the heterotopic sebaceous glands were immunoreactive for keratin 14. The histogenesis of this extremely rare lesion is not completely clear. There have been some reports on ectopic esophagus sebaceous glands combined with esophageal cancer or gastric cancer. However, malignant transformation of the ectopic sebaceous gland itself has not yet been reported on. This case was regularly followed up for 12 months, and no interval change or malignant transformation was found both endoscopically and histologically.

키워드

참고문헌

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