• Korean Journal of Head & Neck Oncology
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• v.23 no.2
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• pp.199-201
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• 2007

피지선종(sebaceous adenoma)은 피지선 분화를 보이는 신생물 중 가장 흔한 종양으로 피지선이 정상적으로 많이 분포하는 안면부, 두피부, 안검부 등에 주로 발생하나 안검에서는 비교적 드물게 발생한다. 피지선종은 피부부속기 종양 중 발생빈도가 아주 낮으며 안면부 중에도 피지선이 많이 분포하는 비부와 협부에 주로 발생하며 종괴 형성으로 인한 이물감이나 소양감, 출혈, 궤양형성등의 증상을 동반한다. Shields 등의 보고에 의하면 내안누구에 발생한 신생물 57예중에서 피지선종은 2예만이 존재할 정도로 극히 드물다고 하였다. Font와 Rishi도 피지선종의 안검 발생에 대하여 상안검과 하안검은 각각 같은 빈도로 발생한다고 하였으며 내안각 피지선종은 단 1예만을 보고하였다. 이에 저자들은 내안누구의 피지선에서 발생한 피지선종을 경험하고 문헌고찰과 함께 그 1예를 보고하고자 한다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.26 no.3
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• pp.284-292
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• 2000

내인성 산화질소는 산화질소 합성효소에 의하여 합성되며 여러 분비선에서 다양한 기능을 하리라 추측되고 있다. 구강주위 외분비선은 형태적으로 유사하나 분비물의 성분과 분비량은 서로 달라 이들 조직에서 산화질소 동위효소의 분포와 기능을 추론함은 흥미 있는 일이다. 또한 구강주위 외분비선과 분비선의 지배신경의 산화질소동위효소의 분포에 관한 보고는 희박하다. 본 연구는 흰쥐구강 주위 외분비조직, 즉 3대 타액선, 혀의 소타액선, 누선 그리고 구강점막의 피지선과 지배신경 및 신경절에서 eNOS와 nNOS의 분포를 면역조직화학 방법에 의하여 관찰하여 다음의 결과를 얻었다. nNOS는 악하선신경절, 대타액선의 분비도관 주위의 신경절후신경섬유, 혀의 소타액선 주위의 신경절후섬유, 누선에서 강한 양성반응을 보였다. nNOS는 대타액선과 근상피세포에서 중등도의 양성반응을 보였고 이중 이하선에서 반응이 가장 약하였으며, 피지선의 분비관에서 약한 반응을 보였다. 그러나 상교감신경절과 삼차신경절, 소타액선의 분비관 및 대,소 타액선의 선포에서는 반응이 매우 미약하거나 관찰되지 않았다. eNOS는 혈관의 내피세포와 대타액선의 분비관, 누선의 분비관 및 선포에서 강한 양성 반응을 보였고, 근상피세포에서 중등도의 반응을, 피지선에서 약한 반응을 보였다. 모든 신경절과 신경섬유에서 eNOS의 반응은 음성이었고 타액선의 일부 선포에서는 미약한 면역반응을 보였다. 이상의 결과 eNOS에 의해 합성된 NO는 악안면영역의 외분비선에서 혈류량의 조절과 분비도관의 기능 조절에 관여하고, nNOS에 의한 NO는 외분비선의 자율신경계에서 신경전달물질로의 기능과 분비도관에서의 분비기능 조절에 관여함을 시사하였다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.31 no.3 s.52
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• pp.273-277
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• 2005

This study was performed to develop new cosmeceutical agents with sebosuppressive activity from native plant extracts in Korea. Inhibitory efforts of the extracts on $5{\alpha}-reductase$ (5-AR) were evaluated by enzyme kinetics analysis using UV-spectrophotometric method. Two kinds of enzyme suspensions as 5-AR sources were prepared from rat liver tissue and cultured hSG cells. The sebosuppressive effects were determined by measuring the total lipid quantity produced in cultured hSG cells after incubation with the extracts. As a result, Pinus thunbergii extracts showed the most potent 5-AR inhibitory effects. Its $K_i$ values were 0.0002% and 0.0014% for rat liver 5-AR and human sebaceous gland 5-AR, respectively. Addition of Pinus thunberii extract to hSG cells showed 48% reduction in total lipid production at 0.005% concentration. In conclusion, Pinus thunbergii extracts can be used as a cosmeceutical agent to regulate sebum production and to alleviate the sebum-involved skin diseases, such as acne and seborrheic dermatitis.

• Journal of the Korean Society for Railway
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• v.17 no.1
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• pp.19-27
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• 2014

Urban railway vehicles operate in downtown areas. Due to increases in the number of passengers and changes in the service plans, railway vehicles are expected to operate on sharp curved tracks. However, on these tracks, the running stability of the railway vehicles is significantly decreased and the creepage is increased. Creepage causes the wheel/rail to wear and vibration. Therefore, reducing the creepage helps ensure the running stability and can be beneficial for the environment and cost. In this paper, the longitudinal creepage is analyzed using a railway vehicle model on a sharp curved track. Furthermore, in order to minimize the problems when a railway vehicle runs on a sharp curved track, the characteristics of a bogie are optimized using response optimization.

• Journal of the Korean Society of Fashion and Beauty
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• v.3 no.2 s.2
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• pp.12-17
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• 2005

Efficiency study of chamomile and Thyme essential oil about the basal layer & sebaceous gland in dry-skin induced by surfactant is as following : 1. Formal observation of outer skin layer and basal layer There was refreshing effects about Surfactant induction skin inflammation in Chamomile, Thyme essential oil processing group but effect in surface layer appeared by higher thing in Chamomile essential oil and it could know that thing which do not use Thyme essential oil in case Thyme essential oil is ultraviolet rays allergy at skin care because Melanocyte appear on the surface is bigger than Chamomile essential oil that it was usefully reaction in basal layer. 2. Formal observation result of sebaceous glands. There are few damages in all group but there is recuperative through excessive water damage by excessive a sebaceous gland made of mulberry bark secretion because Thyme essential oil application group cause chapped skin phenomenon after surface-active agent processing but is seen that difference does not exist greatly and Thyme essential oil that general skin is strong in permeation is effective, but Surfactant induction skin inflammation estimates that Chamomile essential oil is effective. Therefore, it was considered that use of Chamomile essential oil is effectiveness than Thyme essential oil by essential oil used for recovery after damage of inflammation etc..

• Journal of Chest Surgery
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• v.39 no.9 s.266
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• pp.729-732
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• 2006

Mediastinal teratoma is one of the most common lesions found in the anterior mediastinum, accounting for $8\sim13%$ of all mediastinal tumors. This tumor is incidentally detected by routine chest roentgengography, but pericardial perforation or pleural effusion occurs rarely. In our patient cardiac tamponade was developed due to anterior chest wall contusion, we confirmed the anterior mediastinal tumor. Vital signs were stabilized after the pericardiocentesis, and the patient underwent the tumor resection in the anterior mediastinum for a definite treatment. On histologic examination, the tumor revealed cystic structures composed of mature squamous epithelium, pilosebaceous glands, mature fat tissue, gastrointestinal mucosa, respiratory epithelium, and pancreatic tissues.

• Journal of Chest Surgery
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• v.37 no.8
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• pp.711-714
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• 2004

We report a case of mature cystic teratoma of the anterior mediastinum that ruptured into the pulmonary artery requiring an emergent surgical treatment. A 39-year-old woman presented an episode of massive hemoptysis and treated with bronchial artery embolization (BAE). On the 10th day after BAE, however, she developed sudden massive hemoptysis and had a deteriorated mental status. For a definitive treatment, she underwent the left pneumonectomy and the tumor resection in the anterior mediastinum. On histologic examination, the tumor disclosed cystic structures composed of mature squamous epithelium, pilosebaceous glands, mature fat tissue, cartilage and bone tissue. Also, there was intrapulmonary hemorrhage due to left pulmonary artery invasion of the tumor.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2022.06a
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• pp.329-330
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• 2022

태평양 도서국은 간선항로와 먼 거리, 적은 물동량, 수출입 불균형 등으로 해상운임이 높게 형성되어 있으며, 기후변화에 취약하여 항만운영에 제약이 많은 등 해상운송이 상당히 열악한 실정이다. 또한 해상운송 의존도가 상당히 높은 반면, 정기선 연계정도는 상당히 낮아 해운물류 경쟁력을 향상 필요성이 증대되고 있다. 따라서 본 연구에서는 사회연결망분석(SNA)를 통해 14개 태평양 도서국의 국가 간 해상교역 구조를 파악하고 이를 통해 해상운송망 강화를 위한 방안을 제시하였다. 분석 결과, 대상국가 간 교역구조는 점차 복잡해지고 있으며, 점차 피지, 사모아, 파푸아뉴기니 등을 중심으로 Hub-spoke 체제의 해상운송 네트워크가 형성되고 있다. 역내 해상운송망 강화를 위해서는 분석결과에서 도출된 역내 주요 항만을 환적항으로 개발하여 해상운송 연계성을 강화하고, 카보타지 허용을 통한 정기선 입항빈도 증대, 인프라 개선을 통한 항만 운영탄력성 강화 등이 필요하다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.4
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• pp.311-319
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• 2012

Seborrheic dermatitis (SD) is the skin disease occurred because of Malassezia yeast which grows on the skin and scalp, and this yeast lives on sebum lipid, and their metabolite, free lipid acids are thought to be the main irritant on skin. To find out effective cosmeceutical ingredients to treat SD symptoms, we established novel cell-based in vitro model mimicking SD symptoms. This in vitro model adopted the co-culture system with primary sebocyte & HaCaT keratinocyte. We used M. globosa yeast extract, arachidonic acid, linoleic acid and dihydrotestosterone as SD inducers. In the co-culture system with optimized concentrations for SD-inducing cocktail, the production of IL-8 and sebum lipids increased up to 2-fold, and then we screened with commercial essential oils by monitoring IL-8 as a key inflammatory biomarker. Then we found that Cinnamomum zeylanicum oil, Mentha arvensis oil effectively down-regulated IL-$1{\alpha}$, IL-6, IL-8 cytokines which over-produced by SD-inducing cocktail. Additionally, two essential oils also showed inhibitory effect on sebum lipid synthesis from primary sebocyte and growth inhibitory effect to M. globosa yeast (MICs were lower than 0.0625 %). Our recent results suggest that Cinnamomum zeylanicum oil and Mentha arvensis oil could be effective natural herbal remedies to relieve or protect scalp seborrheic dermatitis.

• Journal of Life Science
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• v.18 no.3
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• pp.414-417
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• 2008

A 4-year-old female beagle with progressive exophthalmos and which had a neoplastic mass with diameter of 1.4 cm in the left lower ocular adnexa. Histologically, the mass was composed of hyper-plastic lobules and tubular structures separated by fibrous septum. The well differentiated sebaceous gland forming various sized lobules, and infiltration of mast cells and mononuclear inflammatory cells were observed. Apical decapitation secretion of these tubular structures with basophilic materials in their lumen showed mild sebaceous gland metaplasia. Immunohistochemical studying, cell groups were positive in ${\alpha}-SMA$ and vimentin. The primary tumor was diagnosed as adenocarcinoma originated from moll gland and meibomian gland of the eyelid, and the infiltrating intraocular neoplasm was diagnosed as a malignant mixed tumor.