대한치과교정학회지 (The korean journal of orthodontics)

  • 제40권4호
  • /
  • Pages.212-226
  • /
  • 2010
  • /
  • 2234-7518(pISSN)
  • /
  • 2005-372X(eISSN)
대한치과교정학회 (The Korean Association Of Orthodontists)
권호 표지
DOI QR코드

DOI QR Code

치간 삭제 후 불소 또는 수산화인회석 도포 시 재광화 및 탈회억제에 관한 연구

Effect of remineralization and inhibition to demineralization after fluoride gel or hydroxyapatite paste application on stripped enamel

  • 홍현실 (원광대학교 치과대학 치과교정학교실) ;
  • 김호영 (원광대학교 치과대학 치과교정학교실) ;
  • 성지영 (원광대학교 치과대학 치과교정학교실) ;
  • 조진형 (원광대학교 치과대학 치과교정학교실) ;
  • 김상철 (원광대학교 치과대학 치과교정학교실)
  • Hong, Hyun-Sil (Department of Orthodontics, School of Dentistry, Wonkwang University) ;
  • Kim, Ho-Young (Department of Orthodontics, School of Dentistry, Wonkwang University) ;
  • Sung, Ji-Young (Department of Orthodontics, School of Dentistry, Wonkwang University) ;
  • Cho, Jin-Hyoung (Department of Orthodontics, School of Dentistry, Wonkwang University) ;
  • Kim, Sang-Cheol (Department of Orthodontics, School of Dentistry, Wonkwang University)
  • 투고 : 2009.09.29
  • 심사 : 2009.12.02
  • 발행 : 2010.08.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

치간 삭제 후 재광화 및 치아우식 예방법을 찾기 위한 노력의 일환으로 1.23% 인산화불소 젤 또는 5%, 10% 수산화인회석함유 페이스트를 치간 삭제된 법랑질 표면에 도포하였고, 그 후 젖산탈회용액으로 처리하였다. 법랑질 표면의 재광화 및 탈회 후 결정구조 변화를 주사전자현미경으로 관찰하고 칼슘, 인, 불소 함량 등의 변화를 energy dispersive X-ray spectroscopy로 분석해서 비교하였다. 치간 삭제 후 5%, 10% 수산화인회석함유 페이스트를 도포한 군에서 칼슘과 인 함량이 증가하였고, 1.23% 인산화불소 젤 도포 군에서는 불소 함량이 증가하였다. 또한 모든 재광화 제제에서 법랑질 표면이 매끄럽고 부드러워졌으며 결정구조가 작고 치밀해짐을 관찰할 수 있었다. 10% 수산화인회석함유 페이스트로 재광화한 군은 탈회 후에도 칼슘과 인 함량이 증가된 채로 유지되었고, 5% 수산화인회석함유 페이스트로 재광화한 군은 탈회 후 인 함량이 증가된 채로 유지되었다. 치간 삭제 후 탈회 처리 시 대조군의 법랑질은 파괴양상이 심해 거친 굴곡으로 이루어진 불규칙한 표면 상태를 나타내었으나 불소 및 수산화인회석으로 재광화한 군에서는 법랑질의 파괴양상이 적어 작은 결정입자들과 미세공극이 유지되었다.

Objective: The aim of this study was to evaluate the effect of remineralization and inhibition to demineralization after fluoride gel (acidulated phosphate fluoride, APF) or hydroxyapatite (HAp) paste application on interdentally stripped teeth. Methods: After interdental stripping, 1.23% APF or 5%, 10% HAp paste were applied for 7 days for remineralization. Afterwards, teeth were exposed to lactate carbopol buffer solution for demineralization. Scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS) were used to compare change in surface contents and crystal structures after remineralization, and then after demineralization. Results: EDS analysis indicated that calcium (p < 0.001) and phosphate (p < 0.01) contents were increased after 10% HAp paste application on stripped enamel, calcium (p < 0.05) and phosphate (p < 0.01) contents were increased after 5% HAp paste application, and fluoride (p < 0.01) contents were increased after 1.23% APF application. SEM image showed that enamel surfaces became smoother and crystal structures became small and compact after APF or HAp application. After demineralization, calcium (p < 0.05) and phosphate (p < 0.05) contents remained increased on the enamel remineralized with 10% HAp paste, and phosphate (p < 0.05) contents remained increased on the enamel remineralized with 5% HAp paste. After demineralization, surfaces looked less destroyed in the enamel remineralized beforehand than those of the control, and small pores between crystal structures, formed by remineralization were remained. Conclusions: Hydroxyapatite paste and fluoride gel were helpful to remineralize and inhibit deminerlization on stripped enamel.

키워드

참고문헌

  1. Bolton W A. Disharmony in tooth size and its relation to the analysis and treatment of malocclusion. Angle Orthod 1958; 28:113-30.
  2. Tuverson DL. Anterior interocclusal relations. Part I. Am J Orthod 1980;78:361-70. https://doi.org/10.1016/0002-9416(80)90018-4
  3. Sheridan JJ. Air-rotor stripping update. J Clin Orthod 1987;21: 781-8.
  4. Blake M, Bibby K. Retention and stability: a review of the literature. Am J Orthod Dentofacial Orthop 1998;114:299-306. https://doi.org/10.1016/S0889-5406(98)70212-4
  5. Radlanski RJ, Jager A, Schwestka R, Bertzbach F. Plaque accumulations caused by interdental stripping. Am J Orthod Dentofacial Orthop 1988;94:416-20. https://doi.org/10.1016/0889-5406(88)90131-X
  6. Radlanski RJ, Jager A, Zimmer B. Morphology of interdentally stripped enamel one year after treatment. J Clin Orthod 1989; 23:748-50.
  7. Twesme DA, Firestone AR, Heaven TJ, Feagin FF, Jacobson A. Air-rotor stripping and enamel demineralization in vitro. Am J Orthod Dentofacial Orthop 1994;105:142-52. https://doi.org/10.1016/S0889-5406(94)70110-5
  8. Joseph VP, Rossouw PE, Basson NJ. Orthodontic microabrasive reproximation. Am J Orthod Dentofacial Orthop 1992; 102:351-9. https://doi.org/10.1016/0889-5406(92)70051-B
  9. Kim KN, Yoon YJ, Kim KW. A study on the enamel surface texture and caries susceptibility in interdentally stripped teeth. Korean J Orthod 2001;31:567-78.
  10. Row J, Chun YS. A comparative study of roughness of enamel surface to various interdental enamel stripping methods in vitro. Korean J Orthod 1999;29:483-90.
  11. Bretas SM, Macari S, Elias AM, Ito IY, Matsumoto MA. Effect of 0.4% stannous fluoride gel on Streptococci mutans in relation to elastomeric rings and steel ligatures in orthodontic patients. Am J Orthod Dentofacial Orthop 2005;127:428-33. https://doi.org/10.1016/j.ajodo.2003.12.024
  12. Chadwick BL, Roy J, Knox J, Treasure ET. The effect of topical fluorides on decalcification in patients with fixed orthodontic appliances: a systematic review. Am J Orthod Dentofacial Orthod 2005;128:601-6. https://doi.org/10.1016/j.ajodo.2004.07.049
  13. Mizrahi E. Enamel demineralization following orthodontic treatment. Am J Orthod 1982;82:62-7. https://doi.org/10.1016/0002-9416(82)90548-6
  14. Saxton CA. Scanning electron microscope study of the formation of dental plaque. Caries Res 1973;7:102-19. https://doi.org/10.1159/000259835
  15. Kim MY, Kwon HK, Kim BI. The comparison of remineralizing effect on mouthrinse containing nano sized or micro sized hydroxyapatite. J Korean Acad Dent Health 2006;30:325-34.
  16. Lee YE, Back HJ, Jeong SH, Choi YH, Song KB. Effect of hydroxyapatite containing dentifrice on the remineralization of early incipient carious lesion. J Korean Acad Dent Health 2007;31:305-18.
  17. Barone M, Malpassi M. Clinical trial of a 15% supermicronized hydroxyapatite gel for dentin hypersensitivity. G Ital Endod 1991;5:43-7.
  18. HUttemann RW, Strubel G, Rzekpa-Glinder V, Donges H. Investigation of utility and mechanics of use of hydroxyapatite for therapy of hypersensitive tooth root. ZWR 1989;98:240-5.
  19. Frazier MC, Southard TE, Doster PM. Prevention of enamel demineralization during orthodontic treatment: an in vitro study using pit and fissure sealants. Am J Orthod Dentofacial Orthop 1996;110:459-65. https://doi.org/10.1016/S0889-5406(96)70050-1
  20. Li L. The biochemistry and physiology of metallic fluoride: action, mechanism, and implications. Crit Rev Oral BioI Med 2003;14:100-14. https://doi.org/10.1177/154411130301400204
  21. Bassin EB, Wypij D, Davis RB, Mittleman MA. Age-specific fluoride exposure in drinking water and osteosarcoma (United States). Cancer Causes Control 2006;17:421-8. https://doi.org/10.1007/s10552-005-0500-6
  22. Silverstone LM. Observations on the dark zone in early enamel caries and artificial caries-like lesions. Caries Res 1967;1: 260-74.
  23. Margolis HC, Murphy BJ, Moreno EC. Development of caries- like lesions in partially saturated lactate buffers. Caries Res 1985;19:36-45. https://doi.org/10.1159/000260827
  24. Clarkson BH, Krell D, Wefel JS, Crall J, Feagin FF. In vitro caries-like lesion production by Streptococcus mutans and Actinomyces viscosus using sucrose and starch. J Dent Res 1987;66:795-8. https://doi.org/10.1177/00220345870660031801
  25. Boyle EL, Higham SM, Edgar WM. The production of subsurface artificial caries lesions on third molar teeth. Caries Res 1998;32:154-8. https://doi.org/10.1159/000016446
  26. Arends J, Schuthof J, Jongebloed WG. Lesion depth and microhardness indentations on artificial white spot lesions. Caries Res 1980;14:190-5. https://doi.org/10.1159/000260453
  27. Silverstone LM. Structure of carious enamel, including the early lesion. Oral Sci Rev 1973;3:100-60.
  28. Herkstroter FM, Noordmans J, ten Bosch JJ. Wavelength-independent microradiography: its use to measure mineral changes in curved and thick samples. Caries Res 1990;24:399.
  29. ten Bosch JJ, van der Mei HC, Borsboom PC. Optical monitor of in vitro caries. A comparison with chemical and microradiographic determination of mineral loss in early lesions. Caries Res 1984;18:540-7. https://doi.org/10.1159/000260818
  30. Kim SR, Hong SJ, Roh BD, Lee CY, Kum KY. The remineralizing effects of early enamel carious lesion by supersaturated buffer solution under pH cycling model. J Korean Acad Conserv Dent 2001;26:341-9.
  31. Hicks J, Garcia-Godoy F, Flaitz C. Biological factors in dental caries: role of remineralization and fluoride in the dynamic process of demineralization and remineralization (part 3). J Clin Pediatr Dent 2004;28:203-14. https://doi.org/10.17796/jcpd.28.3.w0610427l746j34n
  32. Lee KH. Effect of fluoride and calcium on enamel remineralizadon in vitro. J Korean Acad Pediatr Dent 2004;31:624-9.
  33. Murray JJ, Rugg-Gunn AJ. Fluorides in caries prevention. 2nd ed. Bristol: Jone Wright & Sons; 1982. p. 100-21.
  34. Alexander SA, Ripa LW. Effects of self-applied topical fluoride preparations in orthodontic patients. Angle Orthod 2000;70: 424-30.
  35. Rogers GA, Wagner MJ. Protection of stripped enamel surfaces with topical fluoride applications. Am J Orthod 1969;56:551-9. https://doi.org/10.1016/0002-9416(69)90191-2
  36. Yamazaki H, Litman A, Margolis Hc. Effect of fluoride on artificial caries lesion progression and repair in human enamel: regulation of mineral deposition and dissolution under in vivo-like conditions. Arch Oral BioI 2007;52:110-20. https://doi.org/10.1016/j.archoralbio.2006.08.012